NAME INDICATION ACTION ADVERSE ROUTE NURSING

REACTION AND RESPONSIBILITY

DOSAGE

Generic name: For pain on Exhibits antipyretic, GI: dyspepsia, 80mg/tab Assess for
integumentary anti-inflammatory and heartburn,anorexia, 1tab p pain:type,
ASPIRIN structures,myalgia, analgesic effects. The nausea,epigastric lunch PO locationand
discomfort,potentia pattern
headache, antipyretic effect is
Brand name: tion of pepticulcer
dysmenorrhea,gout. due to an action on the Note for asthma
Arthrinol, hypothalamus, Allergic:
Arthrisin,Asper Arthritis, SLE,acute resulting in heat loss Bronchospasm,asth Monitor
rheumatic fever ma-like renal,LFTs and
gum Bayer by vasodilation of
symptoms,anaphyla CBC
Aspirin, Contraindications: peripheral blood
xis, skin
Coryphen,Easpi vessels. Anti – Determinehistory
Hypersensitivity to rashes,urticaria
rin, inflammatory effects of pepticulcers
salicylates, severe Hematologic: orbleedingtenden
Ecotrin,Empiri are mediated by a
anemia, history of cies.
n, Entrophen blood coagulation decrease in
prolongation of
defects, vitamin K prostaglandin Precautions:
bleedingtime,
deficiency, 1 week synthesis. It also thrombocytopenia,l
before and after decreases platelet eucopenia, Do not use
surgery,pregnancy in aggregation. inchildren
the last trimester Other: Thirst, withchicken pox
fever,dimness of orflu symptoms
vision
Lactation
 NAME INDICATION ACTION CONTRAINDICATIO ROUTE AND NURSING RESPONSIBILITY
N/ DOSAGE
ADVERSE
REACTION
GENERIC Paracetamol may Contraindication Dose:500 mg Assess patient’s fever
NAME: -To relieve mild to moderate cause analgesia : 1 tab or pain:
pain due to things such as by inhibiting CNS
Paracetamol headache,muscle and joint prostaglandin Hypersensitivity Route:Oral type of pain,location,
pain,backache and period to acetaminophen Frequency:q intensity,duration,
synthesis. The
pains. It is also used to bring or phenacetin; use temperature,and
mechanism
BRAND down a high temperature. For with alcohol diaphoresis.>Assess
NAME: this reason,paracetamol can of morphine is allergicreactions: rash,urticaria; if
be given to children afte believed to Adverse reaction: these occur,drug may have to
Biogesic rvaccinations to prevent post- involve decreased Hematologic: bediscontinued.>Teach patient
immunization pyrexia. permeability of torecognize signs of chronic
the cell membrane hemolyticanemia, overdose:bleeding,
tosodium, which leukopenia,neutro bruising,malaise, fever,
penia,pancytopeni sorethroat.>Tell patient to
results in
a,thrombocytopeni notifyprescriber for pain/fever
diminished a. lasting for morethan 3 days.
transmission
of pain impulses Hepatic:
therefore
liver damage,
analgesia
jaundice

Metabolic:

hypoglycemia

Skin:

rash,urticuria
 NAME INDICATION ACTION CONTRAINDICATIO ROUTE AND NURSING RESPONSIBILITY
N/ DOSAGE
ADVERSE
REACTION
GENERIC Short-term managementof Anti-inflammatory Contraindicated Dosage:
NAME: pain (up to 5 days) andanalgesic withsignificant 30mg (3 doses) Renal impairment,Impaired
activity;inhibits renalimpairment, hearing,allergies, hepatic,Skin
Ketorolac prostaglandinsand aspirinallergy, Route: color and lesions,orientation,
Tromethamine leukotriene recent IVTT reflexes,peripheral
synthesis GI bleed sensation,clotting times,
BRAND orperforation Use Frequency: CBC,adventitious soundsBe
NAME: cautiouslywith Every 6 hour aware that patientmay be at risk
impaired hearing; for CVevents, GI bleeding,renal
Torado allergies; toxicity, monitor accordingly.
hepaticconditions Keep emergency equipment
readily available at time of initial
Adverse reaction: dose, in case of severe
hypersensitivity reaction.Protect
CNS:headache,diz drug vials from light.Administer
ziness,somnolence every 6 hrs to maintain serum
,insomnia,fatigue, levels and control pain
dizzinesstinnitus,o
phthalmologic
effects
 NAME INDICATION ACTION CONTRAINDICATIO ROUTE AND NURSING RESPONSIBILITY
N/ DOSAGE
ADVERSE
REACTION
GENERIC Short-term treatment of Gastric acid-pump Diarrhea, nausea DOSAGE: 40g
NAME: doudenal ulcer; first line inhibitor: suppresses and vomiting, Assess Vital Signs
gastric acid secretion fatigue, FREQUENCY:
therapy in treatment of
Omeprazole by specific inhibition of constipation, OD
heartburn or ROUTE: IVT Check for abdominal Pain,
the hydrogen-
gastroesophageal reflux emesis, Diarrhea or constipation.
potassium ATP as
BRAND disease (GERD) enzyme system at the
NAME:
secretory surface of
Long-term therapy; Evaluate fluid and intake
the gastric parietal
Prillosec treatment of pathologic cells; blocks the final
hypersecretory step of acid
condition Watch for elevated liver function
production. test results

Tell patient to take 30-60 minutes

before a meal, preferably in
morning.

Instruct patient to swallow

capsules or tablets whole and no
to chew or crash them.

Caution patient to avoid driving

and other hazardous activities
until he know drug effects
concentration and alertness
NAME INDICATION ACTION CONTRAINDICATIO ROUTE AND NURSING RESPONSIBILITY
N/ DOSAGE
ADVERSE
REACTION
GENERIC Inhibits bacterial DNA Inhibits bacterial DNA Contraindicated in Dose:400 mg -Assess for infection prior to and
NAME: synthesis by inhibiting synthesis by inhibiting hypersensitivity, Route:IV during therapy.-Obtain specimens
DNA gyrase. DNA gyrase.Therapeutic cross-sensitivity Frequency:Q1 for culture and sensitivity before
Ciprofloxacin Effects:Death of among agents initiating therapy.First dose may
Therapeutic Effects: susceptible be given before receiving results.
may occur.Use
BRAND Death of susceptible bacteria.Spectrum: Broad To prevent development of
activity includes many cautiously in
NAME: bacteria. underlying CNS resistant bacteria,therapy should
gram-positive pathogens. only be used to treating infections
pathology, renal
Fluoroquinolone Spectrum: Broad that are proven or strongly
impairment,
activity includes many suspected to because by
gram-positive cirrhosis susceptible bacteria.-Observe for
pathogens. signs and symptoms of
Adverse effect: anaphylaxis (rash,pruritus,
CNS: laryngeal edema,
Seizures,dizziness, wheezing).Discontinue drug and
drowsiness,heada notify physician immediately if
che, these problems occur.
insomnia,acute
psychoses,agitatio
n,
confusion,hallucin
ations,increased
intracranial
pressure,tremors.
GI:pseudomembra
nouscolitis,
abdominalpain,
diarrhea,nausea,
altered tasteGU:
interstitialcystitis,
vaginitisDerm:
rashEndo:hypergly
cemia,hypoglycae
miaLocal: phlebitis
at IVsiteMS:
tendinitis,tendon
ruptureMisc:hyper
sensitivityreaction
s
includinganaphyla
xis,Stevens-
Johnson
NAME INDICATION
GENERIC infections caused by sensitive
NAME: staphylococci,streptococci,
pneumococci,
Clindamycin bacteroides,fusibacterium,clo
stridium perfringens, and
other sensitive aerobic and
anaerobic organisms.-
BRAND endocarditis prophylaxis for
NAME: dental procedures in patients
allergic to penicillin-acne
Cleocin, Dalacin vulgaris-bacterial vaginosis-
pneumocystis jiroveci
(carinii) pneumonia-
toxoplasmosis(cerebral or
ocular) immunocompromised
patients
ACTION CONTRAINDIC ROUTE AND NURSING RESPONSIBILITY
ATION/ DOSAGE
ADVERSE
REACTION
Contraindicated in Route: IVT assess patients infection before
ANTIBIOTIC; patients Dosage: 600-2700 and regularly through out
Anti- infectivess hypersensitive to mg/day therapy-before giving first dose,
drug or obtain specimen for culture and
lincomycin-use sensitivity test, begin therapy
- inhibits bacterial cautiously in pending results.-monitor renal,
proteinsynthesis patients with renal hepatic,and hematopoetic
by binding to or hepatic disease, functions during prolonged
50Ssubunit of asthma,history of therapy.-be alert for adverse
ribosome.- hinders GI disease, or reactions and drug interactions-if
or killssusceptible significant adverse GI reaction so ccurs,
bacteria allergies monitor patients hydration.-teach
patient how to store oral
CNS: solution.-tell patient to take entire
headacheCV:Thro amount prescribed even after he
mbophlebitisEEN feels better.-warn patient that
T: pharyngitisGI: I.M.injection may be painful-
abdominal instruct patient to report diarrhea
pain,Anorexia, and to avoid self-threatening
bloodyor tarry psudomembranuscolitis-tell
stools,constipation patient receiving drug I.V. to
,diarrhea,dysphagi report discomfort at infusion sit
a,esophagitis,flatul
ence, nausea,
psuedomembranus
colitis, unpleasant
or bitter
taste,vomiting.
NAME INDICATION ACTION CONTRAINDIC ROUTE AND NURSING RESPONSIBILITY
ATION/ DOSAGE
ADVERSE
REACTION
GENERIC Adjunct in the management Depress the CNS, CNS Route: Monitor BP, PR,RR prior to
NAME: of: probably by :1) dizziness2) IM periodically throughout therapy
1) Anxiety 2) Preoperative potentiating drowsiness3) Dosage: and frequently during IV
Diazepam sedation 3) Conscious GABA, lethargy4) 10mg therapy.- Assess IV site
sedation- Provides light aninhibitory hangover 5) Frequency: frequently during administration,
anesthesia and anterograde neurotransmitter.- headache6) As needed diazepam may cause phlebitis
BRAND amnesia- Treatment of status Produces skeletal depression- and venous thrombosis.-
NAME: epilepticus/ uncontrolled muscle relaxation EENT: Prolonged high-dose therapy may
seizures- Skeletal muscle by inhibiting 1) blurred vision- lead to psychological or physical
Valium relaxant- Management of the spinal RESP: dependence. Restrict amount of
symptoms of alcohol polysynaptic 1) respiratory druga vailable to patient. Observe
withdrawal afferent depression- depressed patients closely for
pathways.- Has CV suicidal tendencies.- Observe and
Classification: Antianxiety anticonvul-sant :1) hypotension- record intensity, duration and
agents,anticonvulsants,sedati properties due to GI: location of seizure activity. The
ve/hyptonics,skeletal muscle enhanced 1) constipation2) initial dose of diazepam offers
relaxants presynaptic inhibi- diarrhea3) seizure control for 15-20 min
tion.Therapeutic nausea4) after administration.- IM
effects:(1) Relief vomiting- injections are painful and
of Anxiety(2) DERM: erratically absorbed. If IM route
Sedation(3) 1) rashes is used,inject deeply into deltoid
Amnesia(4) - LOCAL: muscle for maximum absorption.-
Skeletal muscle 1) pain (IM)2) Caution patient to avoid taking
relaxant(5) phlebitis (IV)3) alcohol or other CNS depressants
Decreased seizure venous thrombosis concurrently with this
activity medication.- Effectiveness of
therapy can bed emonstrated by
decrease anxiety level;control of
seizures; decreased
tremulousness
NAME INDICATION ACTION CONTRAINDICA ROUTE AND NURSING RESPONSIBILITY
TION/ DOSAGE
ADVERSE
REACTION
GENERIC Indications: Atorvastatin Contraindication: Dosage: Stress that atorvastatin is an
NAME: Reduction of risk of stroke competitively Hypersensitivity, 20mg adjunct to
and heart attack in type 2 inhibits HMG- active liver Frequency: –
Atorvastatin diabetes patients without CoA reductase, disease or Once daily 2000H not a substitute for low-
evidence of heart disease but the enzyme that unexplained Route: cholesterol diet
with other CV risk factors, catalyses the persistent G-tube
and revascularization conversion of elevations of Tell patient to take drug at the
BRAND procedures in patients HMG-CoA to serum same time each day to maintain
NAME: without evidence of coronary mevalonic acid. transaminase, its effects
heart disease (CHD) but This results in the porphyria,
Dyslipidaemic with multiple risk factors induction of the pregnancy, Instruct patient to take a missed
other than diabetes (eg, LDL receptors, lactation dose as soon as
smoking, HTN, low HDL-C, leading to lowered possible. If it’s almost time
family history of early CHD) LDL-cholesterol for his next dose, he should skip
Patients with CHD, to reduce concentration. the missed dose.
risks of MI, revascularization Absorption:
procedures, hospitalization Rapid from the GI Advise patient to notify
for CHF, and angina tract (oral). prescriber immediately if he
Distribution: develops unexplained muscle
Protein-binding: pain, tenderness, or weakness,
98%. especially if accompanied by
Metabolism: fatigue or feve
Extensively
hepatic; converted
to active inhibitors
of HMG-CoA
reductase.
NAME INDICATION
GENERIC Carbamazepine
NAME: (Tegretol,Tegretol XR
,Equetro,Carbatrol) reduces
Tramadol the effect of tramadol by
increasing its inactivation in
the body. Quinidine
BRAND (Quinaglute,Quinidex)
NAME: reduces the inactivation of
Ultram, Ultram tramadol ,there by increasing
ER the concentration of tramadol
by50%-60%.Combining
tramadol with monoamine
oxidase inhibitors (for
example,Parnate)
ACTION CONTRAINDICATION ROUTE AND NURSING RESPONSIBILITY
/ DOSAGE
ADVERSE
REACTION
Tramadol isused in Tramadol may Assess type, location, and
the management of increasecentral intensity of pain before and 2-3
moderatetomoderat nervous hr (peak) after administration.
elysevere systemand • Assess BP & RR before and
pain.Extendedreleas periodically
respiratorydepres
etablets areused for duringadministration.
moderate sion
whencombined Respiratorydepression has not
tomoderatelysevere occurredwith recommended
chronic painin with
doses.
adults alcohol,anesthetic
• Assess bowel function
whorequirecontinuo s, routinely. Prevention of
ustreatment for an narcotics,tranquili
constipation should beinstituted
extendedperiod zers or
with increased intakeof fluids and
sedativehypnotics. bulk and withlaxatives to
minimizeconstipating effects.
• Assess previous analgesic
history. Tramadol is
notrecommended for
patientsdependent on opioids or
whohave previously
receivedopioids for more than 1
wk;may cause opioid
withdrawalsymptoms