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2014 4 15 Apr 2014 1057013171prefeasibilityofvasudha
2014 4 15 Apr 2014 1057013171prefeasibilityofvasudha
1. Introduction
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Pre-Feasibility Report Vasudha Pharma Chem Limited
TABLE 1
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Pre-Feasibility Report Vasudha Pharma Chem Limited
The company recognized the vital role of R & D for becoming successful in
the generic market. Initially, the focus was on development of cost
effective processes for intermediates related to Piperidone & Piperidine
derivatives. By 2003 -04, the company gained world class expertise and
became the prominent manufacturer of Piperidone & Piperidine
derivatives in the world. Subsequently, the company forward integrated
from intermediates of Piperidone & Piperidine derivatives to APIs and later
on diversified into large product portfolio of about 15 APIs spreading
across several therapeutic areas.
About Proponent
The company has also filed five DMFs with USFDA and five with EDQM of
its APIs. The company has also filed DMFs for its various products with
European, Chinese, Japanese and Russian regulatory authorities.
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Pre-Feasibility Report Vasudha Pharma Chem Limited
3. Project Description
TABLE 2
LIST OF EXISTING PRODUCTS
S.N Quantities in
Name of the Product TPM
o
Group- A
1 Domperidone Maleate 1.20
2 Loratidine 1.87
3 Cyclobenzaprine Hydrochloride 0.30
4 Ketorolac Tromethamine 0.50
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Pre-Feasibility Report Vasudha Pharma Chem Limited
TABLE 3
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Pre-Feasibility Report Vasudha Pharma Chem Limited
Brief process description and process flow charts are given at Annexure
III
The water requirement will be met partly from HMWS and partly from
private suppliers through tankers. The requirement for water in this unit
is for process and domestic purposes. The water balance for daily
consumption is presented below.
TABLE 4.0
Water Balance– Current & Proposed
High TDS and High COD stream would be treated in stripper followed by
MEE and ATFD. The resultant sludge would be disposed to TSDF,
Hyderabad. The Low TDS stream would be treated along with MEE/ATFD
condensates in biological ETP followed by RO. The RO rejects would be fed
back to MEE. The Permeate from RO would be used for cooling tower
make up. Thus the treatment system proposed is based on “Zero Liquid
Discharge” (ZLD) Concept
The schematic diagrams of ETP proposed are given in Figure 1.1 and
Figure 1.2 below
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Pre-Feasibility Report Vasudha Pharma Chem Limited
Fig 1.1
Schematic treatment scheme of high TDS effluents
Effluent from
Process and Strippe Aq. Distillate to
Equalization Neutralization Setting
r
Cement plants/TSDFRecovery
Tank Tank Tank
washings , Scrubber
R&D
RO Reject
To TSDF
MEE Condensate to
Biological
Treatment
Sludge To TSDF
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Pre-Feasibility Report Vasudha Pharma Chem Limited
Domestic effluent
Screen
Effluents from utilities & MEE condensate Chambe
Holding
Tank
Sludge Holding
Tank Sand
filter
Carbon
Filter Press Filter
Sludge to TSDF
Sludge Cake
Ultra filtration
Permeate for re-use RO
Rejects to MEE
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Pre-Feasibility Report Vasudha Pharma Chem Limited
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Pre-Feasibility Report Vasudha Pharma Chem Limited
TABLE 5.0
Solid Wastes and Disposal
Quantity
S.
Description Current After Remarks
No
Expansion
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Pre-Feasibility Report Vasudha Pharma Chem Limited
TSDF facility is about 10.3 KM from the site in Ranga Reddy District which
is created for catering the industries in this area. Transport of Hazardous
wastes to TSDF is done by the Ramkey. In case other hazardous wastes,
authorized recyclers will transport the wastes
4. Site Analysis
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Pre-Feasibility Report Vasudha Pharma Chem Limited
4 Bowrampet NW 5.0
5 Pochampalli N 6.3
6 Goudavalli N 7.2
7 Dundigal NW 9.2
8 Kajipalli NW 8.9
Topo graphic features of the site and 10 KM study area and base map are
given at Fig 1.3 & 1.4.
Plant & Green Belt Photographs are given at Fig. 1.5
Site lay out map is given at Fig 1.6
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Pre-Feasibility Report Vasudha Pharma Chem Limited
Fig 1.3
Topo Sheet of the 10 KM study area
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Pre-Feasibility Report Vasudha Pharma Chem Limited
Fig 1.4
Base map of the study area
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Pre-Feasibility Report Vasudha Pharma Chem Limited
Fig 1.5
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Pre-Feasibility Report Vasudha Pharma Chem Limited
Fig 1.6
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Pre-Feasibility Report Vasudha Pharma Chem Limited
6. Resource requirements
TABLE 7.0
Production facilities/Utilities/ETP – Existing & Proposed
Capacity/ After
S.NO Details No Current Additions expansion
Production facilities
10 Neutralisation tanks KL 35 30 65
11 Stripper ,MEE,ATFD KLD -- 60 60
12 RO & Biological KLD --- 50 50
treatment
The unit currently have 3 acres of land and out of which 0.33 acres of
green belt is developed. The land requirement for proposed expansion
activities will be 2500.0 Square Meters which can be met from existing
open area. Below table provides the land statement. Detailed site lay out
plan outlining current and proposed expansion activities is given at
Figure 1.5
Table 8.0
Land Statement
The Sources of air emissions from the plant are 3 TPH oil fired boiler & 3
TPH coal fired Boiler and proposed 4 TPH coal fired boiler and additional
DG sets
The process emissions from the second phase contain NH3, HCl, Methyl
chloride are scrubbed with caustic and scrubbed waste send to MEE. The
other gases expected in the process are Carbon dioxide, H2 which are let
out into atmosphere Below Table gives current proposed emission sources
from the plant
Table 9.0
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Pre-Feasibility Report Vasudha Pharma Chem Limited
Table No 10.0
Sr Capacity
Name of the solvent MOC
No (KL)
1 2X 20 Methanol SS
2 20 Toluene SS
3 20 Acetone SS
4 20 IPA SS
5 20 Ethyl acetate SS
6 20 Acetic acid HDPE
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Pre-Feasibility Report Vasudha Pharma Chem Limited
7 12 CS Lye MS
8 12 Liquid Ammonia MS
9 10 Sulphuric acid MS
10 25 Secondary Container MS
11 15 Diesel MS
Total maximum storage capacity: 214 KL
9. Project Financial
Project cost
Rs. In
lakhs
Plant& machinery 250.0
Civil & Structural 100.0
Total 350.0
20% on plant &
Pipe lines & insulation machinery 20.0
10% on plant &
Electricals & instrumentation machinery 10.0
8% on plant &
Erection & commissioning & machinery and
painting structures 8.0
Safety & Environment 100.0
Furniture, fixtures, computers,
lighting etc 40.0
Total 528.0
Contingencies & pre-operative
expenses 22.0
Project cost say 5.5 Crores
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Pre-Feasibility Report Vasudha Pharma Chem Limited
Annexure I
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Pre-Feasibility Report Vasudha Pharma Chem Limited
Annexure III
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