MISSION

“MABINI COLLEGES provides quality instruction, research and

MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Mild cortical o Ritalin, Ritalin SR, o Contraindicated CNS: Nervousness,  Be aware that drug has potential for
Methylphenidate stimulant with Metadate ER, with insomnia, dizziness, abuse; use caution with emotionally
hydrochloride CNS actions Methylin hypersensitivity to headache, unstable patients
similar to those Narcolepsy methylphenidate; dyskinesia, chorea,  Apply transdermal patch to clean, dry
Brand Name: of the o Attention deficit marked anxiety, drowsiness, Tics, area of the hip approximately 2hr
Ritalin amphetamines; disorder, tension and Tourette’s before effect needed. Remove after
efficacy in hyperkinetic agitation; syndrome, toxic 9hr. alternate hips
Classification: hyperkinetic syndrome, minimal glaucoma; motor psychosis, blurred  Interrupt drug dosage periodically in
CNS Stimulant syndrome, brain dysfunction in tics, family history vision, children to determine if symptoms
attention deficit children or adults of diagnosis of accommodation warrant continued drug therapy
Dosage: disorders in with a behavioral Tourette’s difficulties  Monitor growth of children on long
Adults: 10-60 children syndrome syndrome, severe CV: Increased or term methylphenidate therapy
mg/day appear characterized by depression of decreased pulse  Ensure that all timed release tablets
Pediatric paradoxical the following endogenous or and BP, and capsules are swallowed whole,
Patients 13-17 and are not symptoms: exogenous origin; Tachycardia, not chewed and crushed
years: 18mg/day understood. moderate to severe normal fatigue angina, cardiac  Dispense the smallest feasible dose
Pediatric distractibility, short states; concurrent arrhythmias, to minimize risk of overdose
patients 6-12 attention span, use within 2 week palpitations  Give before 6 pm to prevent insomnia
year: hyperactivity, MAOI Dermatologic:  Monitor CBC and platelets count
5-10mg/weekly emotional liability, o Use cautiously Rash, urticaria, periodically in patients on long term
Route: oral and impulsivity, not with seizures fever, exfoliative therapy
secondary to disorder; dermatitis, loss of  Monitor BP frequently early in
environmental hypertension; scalp hair treatment
factors or drug Hematologic:  teach the patient to avoid alcohol and
psychiatric dependence, Leukopenia, anemia over the counter drugs it can cause
disorders alcoholism, Other: tolerance, dangerous effects
o Unlabeled use: emotional psychological
Treatment of instability, dependence,
depression in the psychosis, abnormal behavior
elderly, cancer and seizures, with abuse
CVA patients lactation, Arthralgia
pregnancy
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Acts in the CNS to o Narcolepsy o Contraindicated CNS: episodes  Be aware that drug has a high
Dextroamphetamine release o Adjunct with Overstimulation, abuse potential; avoid prolonged
sulfate norepinephrine therapy for hypersensitivity restlessness, use and prescribed sparingly
from nerve abnormal to symptomatic dizziness, insomnia,  Interrupt drug dosage periodically
Brand Name: terminals; in higher behavioral amines, dyskinesia, in children being treated for
Dexedrine, doses also syndrome in tartrazine euphoria, dysphoria, behavioral disorders to determine
Dexedrine releases children (Dexedrine and tremor, headache, if symptomatic response still
spansule, dopamine; (attention- dextroStat); psychotic validates drug therapy
DextroStat suppresses deficit disorder, advance CV: Palpitations,  Monitor growth of children on long
appetite; increase hyperkinetic arteriosclerosis, tachycardia, term amphetamine therapy
Classification: alertness, elevates syndrome) that symptomatic CV hypertension  Dispense the lowest feasible dose
Amphetamine mood; often includes disease, Dermatologic: to minimize risk of over dosage;
CNS Stimulant improves physical psychological, moderate to Urticaria drug should be stored in light
performance, social, severe Endocrine: resistant container.
Dosage: especially when educational hypertension, reversible elevations  Ensure that patient swallows SR
Adults: 10mg/day fatigue and sleep measures hyperthyroidism, in serum thyroxine tablets whole; do not crush, or
Pediatric Patients deprivation have glaucoma, with heavy use chew
3-5 years: caused agitated states GI: Dry mouth,  Give drug early in day to prevent
2.5mg/day impairment; o Use cautiously unpleasant taste, insomnia
Pediatric patients efficacy in with history of diarrhea,  Monitor BP frequently early in
6-12 year: hyperkinetic drug abuse, constipation, therapy
5mg/day syndrome, pregnancy and anorexia and weight
Route: attention deficit in lactation loss
PO children appears GU: Impotence,
paradoxical and is changes in Libido
not understood Other: Tolerance,
psychological
dependence, social
disability with abuse
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Selectively o Treatment o Contraindicated CNS: Aggression,  Monitor patient closely and alert
Atomoxetine blocks the of ADHD with irritability, crying, caregivers of risk
hydrochloride reuptake of as part of hypersensitivity somnolence,  Ensure proper diagnosis before
Brand Name: norepinephrine a total to atomoxetine dizziness, headache, administering to children for behavioral
Strattera at the neuronal treatment or constituents mood swings, syndromes; drugs should not be used
Classification: synapse. The program of Strattera; use insomnia, possible until other causes and concomitants of
Selective mechanism by of MAOIs within suicidal ideation in abnormal behavior are ruled out.
norepinephrine which this the past 14 children  Ensure that drug is being used as part of
reuptake inhibitor action has a days; narrow CV: Palpitations an overall treatment program including
Dosage: therapeutic angle glaucoma Dermatologic: education and psychosocial
Adults and children effect in ADHD o Use cautiously dermatitis, increased interventions.
over 70 kg: 40mg/day is not with sweating  Arrange to interrupt drug dosage
increase after a understood. hypertension, GI: Dry mouth, periodically in children being treated for
minimum of 3 days to tachycardia, CV nausea, decreased behavioral disorders to determine if
target total daily dose of or appetite, constipation, symptoms recur at an intensity that
80 mg given as single cerebrovascular upper abdominal warrants continued drug therapy
dose in the morning or disease, pain, vomiting  Administer drug before 6pm to prevent
two evenly divided pregnancy and GU: Urinary insomnia
doses, in the morning lactation. hesitation, urinary  Monitor growth and weight of children on
and the late afternoon retention, long term atomoxetine therapy
or early evening dysmenorrhea,  Monitor BP early in treatment,
Route: erectile problems particularly with adult patients
PO Respiratory: cough,  Arrange for consult with school nurse for
rhinorrhea, sinusitis school age patients receiving this drug.
Other: fever, rigors,
sinusitis, weight loss,
myalgia
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Acts as an anti- o Treatment of o Contraindicated CNS: Headache,  Possible fatal reactions with
Fluoxetine depressant by depression; most with nervousness, insomnia, MAOIs; do not administer
hydrochloride inhibiting CNS effective in hypersensitivity drowsiness, anxiety, tremor, together; 2-week washout
Brand Name: neuronal uptake of patients with to fluoxetine, dizziness, lightheadedness, period needed.
Prozac serotonin; blocks major depressive pregnancy. agitation, sedation, abnormal  Arrange for lower or less
Classification: uptake of serotonin disorder o Use cautiously gait, seizures frequent doses in elderly
Anti-depressant with little effect on o Treatment of with impaired CV: Hot flashes, palpitations patients with hepatic or
SSRI norepinephrine, OCD hepatic or renal Dermatologic: sweating, renal impairment
little affinity for o Treatment of function, rash, pruritus, acne, alopecia,  Establish suicide
Dosage: muscarinic, bulimia diabetes contact dermatitis precautions for severely
Adults: 20mg/day histaminergic, and o Treatment of mellitus, GI: nausea, vomiting, depressed patients. Limit
Pediatric Patients alpha-adrenergic PMDD(sarafem) lactation, diarrhea, dry mouth, quantity of capsules
8-18years: major receptors o Treatment of seizures, history anorexia, dyspepsia, dispensed; high risk in
depressive panic disorders of suicide constipation, taste changes, children and adolescent
disorder: 10mg/day with or without attempts flatulence, gastroenteritis,  Administer drug in the
Pediatric patients agoraphobia dysphagia, gingivitis morning
7-17year: OCD o Unlabeled use: GU: Painful menstruation,  Monitor patient for response
10mg/day treatment of sexual dysfunction, to therapy for up to 4 weeks
Route: obesity, frequency, cystitis, before increasing dose
PO alcoholism, impotence, urgency, vaginitis  Switch to once a week
numerous Respiratory: URIs, therapy by starting weekly
psychiatric pharyngitis, cough, dyspnea, dose 7 days after last
disorders, chronic bronchitis, rhinitis 20mg/day dose if response
pain, various Others: weight changes, is not satisfactory,
neuropathies asthenia, fever reconsider daily dosing
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Potentiates o Treatment of o Contraindicated with CNS: Somnolence,  Administer once a day in
Paroxetine serotonergic major use of MAOI or dizziness, insomnia, the morning
hydrochloride activity in the depressive thioridazine nervousness, headache,  Shake suspension well
Brand Name: CNS,resulting in disorder o Use cautiously in the anxiety, paresthesia, blurred before using
Paxil anti-depressant o Treatment of elderly; with renal or vision  Ensure that the patients
Classification: effect OCD hepatic impairment, CV: Palpitations, swallow CR tablets
Anti-depressant o Treatment of pregnancy, lactation, vasodilation, orthostatic whole, do not cut, crush
panic disorder suicidal patients hypotension, hypertension or chew
Dosage: o Treatment of Dermatologic: Sweating,  Limit amount of drug
Adults: 20mg/day social anxiety rash, redness given to potentially
Pediatric Patients disorder (social GI: Nausea, Dry mouth, suicidal patients
8-18years: major phobia) constipation, diarrhea,  Abruptly discontinuing the
depressive disorder: o Treatment of anorexia, flatulence, drug may result in
10mg/day generalized vomiting discontinuation symptoms
Pediatric patients anxiety disorder GU: Ejaculatory disorders, (agitations, palpitations);
7-17year: OCD o Treatment of male genital disorders, consider tapering
10mg/day PTSD urinary frequency  Advise patient to avoid
Route: o Treatment of Respiratory: Yawns, using if pregnant or
PO PMDD pharyngitis, cough lactating
o Unlabeled use: Other: Headache, asthenia
treatment of hot
flashes
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Acts as anti- o Treatment of o Contraindicated with CNS: headache,  Use lower dose in elderly
Sertraline depressant by major hypersensitivity to nervousness, drowsiness, patients with hepatic or
Brand Name: inhibiting CNS depressive sertraline. anxiety, tremor, agitation, renal impairment
Zoloft neuronal disorder o Use cautiously with sedation, abnormal gait,  Dilute oral concentrate in
Classification: uptake of o Treatment of impaired hepatic or psychosis seizures, vision 4 oz. water, ginger ale,
Anti-depressant serotonin; OCD renal function, changes, flatulence, lemon-lime soda,
SSRI blocks uptake o Treatment of lactation, pregnancy. gastroenteritis, dysphagia, lemonade, or orange
of serotonin panic disorder gingivitis juice only; administer
Dosage: with little effect with or without CV: hot flashes, immediately after diluting
Adults: Major on agoraphobia palpitations, chest pain  Establish suicide
depressive disorder norepinephrine, o Treatment of Dermatologic: sweating, precautions for severely
and OCD:50mg/day muscarinic, PTSD; long term rash, pruritus, acne, contact depressed patients. Limit
maybe increased to up histaminergic, use to prevent dermatitis number of tablets given at
to 200mg/day; dosage and alpha relapse and GI: nausea, vomiting, any time.
should not occur at adrenergic or sustain symptom diarrhea, dry mouth,  Give drug once a day
intervals less than 1 wk. dopaminergic improvement anorexia, dyspepsia, morning or evening
Panic disorder and receptors. o Treatment of constipation, taste changes,  Increase dosage at
PTSD: 25mg after 1- PMDD flatulence, gastroenteritis, intervals of not less than
week increase to 50 mg o Treatment of dysphagia, gingivitis 1 week
once daily social anxiety GU: painful menstruation,  Counsel patient to use
PMDD: 50mg/day disorder (social sexual dysfunction, non hormonal
Social anxiety phobia) frequency, cystitis, contraceptives,
disorder: 25mg/day impotence, urgency, pregnancy should be
increase to 50mg/day vaginitis avoided due to risk to
after 1 wk. range 50- Respiratory: URI’s, fetus
200mg/day pharyngitis, cough,
dyspnea, bronchitis, rhinitis
Pediatric Patients 6- Other: hot flashes, fever,
12years: OCD: back pain, thirst
25Pediatric patients 7-
17year: OCD
50mg/day
Route:
PO
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Centrally acting o Treatment of o Contraindicated with CNS: insomnia, fatigue,  Administer at bed time
Donepezil hydrochloride reversible dementia of the hypersensitivity to dizziness, confusion, ataxia, each day
Brand Name: cholinesterase Alzheimer’s rivastigmine somnolence, tremor,  Provide small frequent
Aricept inhibitor type, including o use cautiously with agitation, depression, meals if GI upset is
Classification: leading to severe dementia sick sinus syndrome, anxiety, abnormal thinking severe
Alzheimer’s disease elevated o Unlabeled GI Bleeding, Dermatologic: rash,  Place orally disintegrating
drugs acetylcholine uses: possible seizures, asthma, flushing, purpura tablet on tongue allow to
Cholinesterase inhibitor levels in the treatment of COPD, pregnancy GI: nausea, vomiting, dissolve and follow with
Dosage: cortex, which vascular and lactation diarrhea, anorexia, water
Adults: 5mg daily at slows the dementia, dyspepsia, constipation,  Notify surgeons that
bedtime for mild to neuronal improvement of flatulence, abdominal pain, patients on donepezil;
moderate disease. May degradation memory in MS hepatoxicity exaggerated muscle
be increase to 10 mg that occurs in patients Other: muscle cramps relaxation may occur if
daily after 4-6 week. 10 Alzheimer’s succinylcholine- type
mg daily for severe disease drugs are used
disease

Route:
PO
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Centrally acting o Treatment of o Contraindicated with CNS: insomnia, tremor,  establish baseline functional
Galantamine selective long mild to moderate allergy to dizziness, fatigue, profile to follow evaluation of
acting dementia of galantimine, severe sedation, somnolence, drug effectiveness.
Brand Name: reversible Alzheimer’s type hepatic impairment, tremor, headache  Ensure at least 4 weeks at
Razadyne cholinesterase o Unlabeled severe renal CV: Bradycardia, each dosage level to
inhibitor; uses: vascular impairment syncope establish effectiveness and
Classification: causes dementia o use cautiously with GI: nausea, vomiting, tolerance of adverse effects.
Alzheimer’s disease elevated moderate renal or diarrhea, anorexia,  Administer with foods in the
drugs acetylcholine hepatic impairment, dyspepsia, abdominal morning and evening to
Cholinesterase inhibitor levels in the GI Bleeding, pain, weight loss decrease GI discomfort
Dosage: cortex, which is seizures, asthma, GU: UTI, hematuria  Mix solution with water, fruit
Adults: initially, 4mg thought to slow COPD, pregnancy, juice or soda to remove
PO bid. If well tolerated the neuronal lactations and CV compliance
after 4 weeks, increase degradation conditions  Ensure the patient swallow
to 8mg. if well tolerated that occurs in ER capsules whole; do not
increase to 12mg. range Alzheimer’s crush or cut or allow patient
1632 mg/day in two disease to chew capsule. Capsule can
divided doses; ER be opened and contents
capsules-initial dose, sprinkled over soft food
8mg/day; titrate to 16-24  Monitor patient for weight
mg/day loss, diarrhea, and
Route: arrhythmias before use and
PO periodically with prolonged
use
 Provide small frequent meals
if GI upset is severe, anti-
emetics may be used if
necessary
 Provide patient safety
measures if CNS effects
occur
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Centrally acting o Treatment of o Contraindicated with CNS: insomnia, fatigue,  establish baseline
Rivastigmine tartrate selective long mild to moderate allergy to donepezil dizziness, confusion, ataxia, functional profile to follow
acting dementia of o use cautiously with somnolence, tremor, evaluation of drug
Brand Name: reversible Alzheimer’s type sick sinus syndrome, agitation, depression, effectiveness.
Exelon inhibitor, o Treatment of GI Bleeding, anxiety, abnormal thinking,  Administer with food in
causes mild to moderate seizures, asthma, syncope the morning and evening
Classification: elevated dementia pregnancy and CV: Bradycardia to decrease GI discomfort
Alzheimer’s disease acetylcholine associated with lactation GI: nausea, vomiting,  Mix solution with water,
drugs level in the Parkinson’s diarrhea, anorexia, fruit juice, or soda to
Cholinesterase inhibitor cortex, which disease dyspepsia, constipation, improve compliance.
Dosage: slows the o Unlabeled flatulence, abdominal pain Dosage of capsules and
Adults: neuronal uses: treatment solution interchangeable.
 Alzheimer’s degradation of behavioral  Apply patch to clean, dry
disease: initial that occurs in effects of lewy- skin once daily. Rotate
dosage 1.5mg/Bid Alzheimer’s body dementia application sites, and
with food. If disease. remove old patch before
tolerated, may applying new one
adjust to higher  Monitor patient for weight
dose at 1.5mg loss, diarrhea,
intervals every 2 arrhythmias before use
weeks. Usual range, and periodically with
6-12 mg/day; should prolonged use.
not exceeded  Provide small, frequent
12mg/day meals if GI upset is
 Parkinson’s severe
dementia:3-12  Provide patient safety
mg/day measures if CNS effects
Route: occur
PO
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Exerts a low to o Treatment of o Contraindicated with CNS: fatigue, headache,  establish baseline
Memantine moderate moderate to allergy to memantine dizziness, confusion, functional profile to follow
hydrochloride affinity for severe dementia o use cautiously with somnolence, hallucinations, evaluation of drug
Brand Name: NMDA receptor of Alzheimer’s pregnancy and agitation, insomnia, anxiety effectiveness.
Namenda sites with no type lactation, renal CV: hypertension,  Administer without regard
Classification: effects on o Unlabeled impairment peripheral edema to food, may take with
Alzheimer’s disease GABA, uses: treatment GI: vomiting, diarrhea, food if GI upset is a
drugs dopamine, of vascular constipation problem; switch to oral
N-Methyl-D-aspartate histamine, dementia GU: UTI, urinary solution if swallowing is
(NMDA) receptor glycine, or incontinence difficult
antagonist adrenergic Respiratory: cough,  Provide patient safety
Dosage: receptor sites; dyspnea, URI, Bronchitis measures if CNS effects
Adults: persistent Other: pain, back pain, occur
Initially 5mg/day, activation of the arthralgia  Establish bowel program
increase at weekly CNS NMDA if constipation becomes
intervals to 5mg receptors by the issue
bid(10mg/day), excitatory amino
15mg/day (5mg and acid glutamate
10mg doses) with a has been
target dose of 20mg/day suggested to
(10mg bid). Use contribute to
solution dosing devise if symptomatology
solution is use of Alzheimer’s
Route: disease
PO
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Mechanism is not o Treatment of o Contraindicated CNS: headache, worsening of  Give with caution and daily
Lithium known; alters manic with organic brain syndromes, fever, monitoring of serum lithium
Brand Name: sodium transport episodes’ hypersensitivity to reversible short term memory levels to patients with renal or
Lithane, duralith in nerve and illness; tatrazine; impairment, dyspraxia CV disease, debilitation, or
(CAN) muscle cells; maintenance significant renal CV: ECG changes, dehydration of life threatening
Carbolith (CAN) inhibits release of therapy to or CV disease; hyperkalemia associated with disorders
Classification: norepinephrine prevent or severe ECG changes, syncope,  Give drug with food or milk or
Anti-manic drug and dopamine but diminish debilitation, tachycardia, bradycardia after meals
Dosage: not serotonin, frequency and dehydration; syndrome, rarely arrhythmias,  Monitor clinical status closely,
Adults: acute from stimulated intensity of sodium depletion, heart failure, diffuse myocarditis, especially during initial stages of
mania: 600mg neurons; slightly subsequent patients on death therapy; monitor for therapeutic
tid or 900mg increases manic diuretics (lithium Dermatologic: pruritus with or serum levels of 0.6-1.2 mEq/L
slow release intraneuronal episodes decreases without rash, maculopapular,  Advise patient that this drug may
form bid to stores of o Unlabeled use: sodium acneiform, and follicular cause serious fetal harm and
produce catecholamine’s; improvement reabsorption and eruptions, cutaneous ulcers, cannot be used during
effective serum decreases of neutrophil hyponatremia edema of ankles or wrist pregnancy
levels between intaneuronal counts in increases lithium Endocrine: diffuse nontoxic  Decrease dosage after acute
1 to 1.5 mEq/L content of second patients with retention) use of goiter, hypothyroidism, manic episodes is controlled
Long term messengers and cancer ACE inhibitors; hypercalcemia associated with  Ensure that patient maintains
use:300mg/tid- may thereby chemotherapy- pregnancy; hyperparathyroidism, transient adequate intake of fluid
qid to produce a selectively induced lactation hyperglycemia, irreversible
serum level of modulate the neutropenia o Use cautiously nephrogenic diabetes insipidus
0.6-1.2 mEq/L responsiveness and in children with protacted which improve with diuretic
Route: of hyperactive with chronic sweating and therapy, impotence
PO neurons that neutropenia diarrhea; suicidal GI: Dysgeusia (taste distortion),
might contribute and HIV or impulsive salty taste, swollen lips
to the manic patients on patients; infection Other: weight gain (5-10kg),
state. zidovudine with fever chest tightness, swollen or
therapy painful joints, eye irritation,
worsening of cataracts,
disturbance of visual
accommodation, leukocytosis
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Exact o Management o Contraindicated CNS: transient, mild drowsiness initially;  Arrange to taper dosage
alprazolam mechanisms of anxiety with sedation, depression, lethargy, apathy, gradually after long term
Brand Name: of action not disorders, hypersensitivity to fatigue, light headedness, disorientation, therapy; especially in
Alprazolam understood; short term benzodiazepines, anger, hostility, episodes of mania and epileptic patients
intensol, main sites of relief of psychoses, acute hypomania, restlessness, confusion,  Do not administer with
niravam, Xanax action may be symptoms of narrow angle crying, delirium, headache, slurred grapefruit juice
the limbic anxiety; glaucoma, shock, speech, dysarthria, stupor, rigidity,  Taper drug slowly decrease
Classification: system and anxiety coma, acute tremor, dystonia, vertigo, euphoria, by no more than 0.5 mg
Anxiolytic, reticular associated alcoholic nervousness, difficulty in concentration, every 3 days
benzodiazepine formation; with intoxication with vivid dreams, psychomotor retardation,
Dosage: increases the depressions depression of vital extrapyramidal symptoms; mild
Adults: anxiety effects of o Treatment of signs, pregnancy paradoxical excitatory reactions during
disorders: GABA, an panic attacks (crosses the first 2 weeks of treatment.
0.25-0.5mg/tid inhibitory with or placenta; risk of CV: bradycardia, tachycardia, CV
Panic neurotransmit without congenital collapse, hypertension, hypotension,
disorder: ter; anxiety agoraphobia malformations, palpitations, edema
initially blocking o Unlabeled neonatal Dermatologic: urticarial, pruritus, rash,
0.5mg/tid, effects occur uses; social withdrawal dermatitis
increase dose at doses well phobia, syndrome), labor EENT: visual and auditory disturbances,
at 3-4 day below those premenstrual and delivery diplopia, nystagmus, depressed hearing,
intervals in necessary to syndrome, (“floppy infant” nasal congestion
increments of cause depression syndrome) GI: constipation, diarrhea, dry mouth,
no more than sedation, lactation (secreted salivation, nausea, anorexia, vomiting,
1mg/day; ataxia in breast milk; difficulty in swallowing, gastric disorders,
ranges of 1- infants become hepatic impairment.
10mg/day have lethargic and lose GU: Incontinence, changes in libido,
been needed weight). urine retention, menstrual irregularities
Route: o Use cautiously Hematologic: elevations of blood
PO with impaired liver enzymes- LDH, alkaline phosphatase,
or renal function, AST, ALT; blood dyscrasias-
debilitation. agrunulocytosis, leukopenia
Other: hiccups , fever, diaphoresis,
paresthesia’s, muscular disturbances
\
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Exact o Manageme o Contraindicated CNS: transient, mild drowsiness initially;  Arrange to taper dosage
chlordiazepoxide mechanisms nt of with sedation, depression, lethargy, apathy, gradually after long term
Brand Name: of action not anxiety hypersensitivity to fatigue, light headedness, disorientation, therapy; especially in
Librium understood; disorders, benzodiazepines, anger, hostility, episodes of mania and epileptic patients
Classification: main sites of short term psychoses, acute hypomania, restlessness, confusion,  Do not administer with
Anxiolytic, action may be relief of narrow angle crying, delirium, headache, slurred grapefruit juice
benzodiazepine the limbic symptoms glaucoma, shock, speech, dysarthria, stupor, rigidity,  Taper drug slowly decrease
Dosage: system and of anxiety; coma, acute tremor, dystonia, vertigo, euphoria, by no more than 0.5 mg
Adults: anxiety reticular anxiety alcoholic nervousness, difficulty in concentration, every 3 days
disorders: 0.25- formation; associated intoxication with vivid dreams, psychomotor retardation,
0.5mg/tid increases the with depression of extrapyramidal symptoms; mild
Panic disorder: effects of depression vital signs, paradoxical excitatory reactions during
initially 0.5mg/tid, GABA, an s pregnancy first 2 weeks of treatment.
increase dose at inhibitory o Treatment (crosses the CV: bradycardia, tachycardia, CV
3-4 day intervals in neurotransmit of panic placenta; risk of collapse, hypertension, hypotension,
increments of no ter; anxiety attacks congenital palpitations, edema
more than blocking with or malformations, Dermatologic: urticarial, pruritus, rash,
1mg/day; ranges effects occur without neonatal dermatitis
of 1-10mg/day at doses well agoraphobi withdrawal EENT: visual and auditory disturbances,
have been needed below those a syndrome), labor diplopia, nystagmus, depressed hearing,
Route: necessary to o Unlabeled and delivery nasal congestion
PO cause uses; (“floppy infant” GI: constipation, diarrhea, dry mouth,
sedation, social syndrome) salivation, nausea, anorexia, vomiting,
ataxia phobia, lactation difficulty in swallowing, gastric disorders,
premenstru (secreted in hepatic impairment.
al breast milk; GU: Incontinence, changes in libido,
syndrome, infants become urine retention, menstrual irregularities
depression lethargic and lose Hematologic: elevations of blood
weight). enzymes- LDH, alkaline phosphatase,
o Use cautiously AST, ALT; blood dyscrasias-
with impaired liver agrunulocytosis, leukopenia
or renal function, Other: hiccups , fever, diaphoresis,
debilitation. paresthesia’s, muscular disturbances
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Mechanism of o Relief of o Contraindicated CNS: disturbed concentration, sedation  Monitor patient carefully
amoxapine action symptoms with and anticholinergic affects, confusion because of the risk of
Brand Name: unknown; of hypersensitivity to (especially in elderly), hallucination, suicidal
TCAs inhibit depression tricyclic drugs disorientation, decreased memory,  Give most at dose at
Classification: the reuptake o Treatment concomitant use feelings of unreality, delusions, anxiety, bedtime if drowsiness,
Anxiolytic, of the of with an MAOI; nervousness, restlessness, agitation severe anticholinergic occur
TCA neurotransmit depression recent MI; CV: orthostatic hypotension,  Reduce dosage if minor side
Dosage: ters accompani myelography hypertension, syncope, tachycardia, effects develop; discontinue
Adults: 50 mg/bid norepinephrin ed with within previous palpitations, MI, arrhythmias, heart block, if serious side effects occur
or tid; gradually e and anxiety 24hr or scheduled precipitation of the heart failure, CVA  Arrange CBC if patient
increased to 100 serotonin, within 48hr, Endocrine: elevated or depressed blood develops fever, sore throat,
mg bid-tid by end leading to an lactation. sugar, elevated prolactin levels, or other sign of infection
of first week if increase in o Use cautiously inappropriate ate ADH secretion  Encourage elderly men with
tolerated. Increase their effects, with EST, GI: dry mouth, constipation, paralytic prostate problems to void
above 300mg/day anticholinergi Preexisting CV ileus, nausea, vomiting, anorexia, before taking drugs
only if it dosage is c at CNS and disorders (severe epigastric distress, diarrhea, flatulence, Teaching points:
ineffective for at peripheral coronary heart dysphagia, peculiar taste, increased  Do not stop this drug
least 2 weeks. receptors disease, salivation, stomatitis, glossitis, parotid abruptly without consulting
Pediatric sedative. progressive heart swelling, abdominal cramps, black your health care provider
patients: not failure, angina tongue.  Avoid using alcohol, other
recommended for pectoris, GU: urinary retention, delayed sleep inducing drugs, and
patients under 16 paroxysmal micturition, dilation of the urinary tract, over the counter drugs
years’ old tachycardia) gynecomastia, testicular swelling in men,  Avoid prolonged exposure
Geriatric angle glucose breast enlargement to sunlight. Use a
Patients: initially glaucoma, Hematologic: bone marrow depression sunscreen or protective
25mg bid-tid, if increased IOP, hypersensitivity: rash, pruritus, garments.
tolerated dosage urinary retention, vasculitis, petechiae, photosensitization,
may be increased urethral spasm, edema, drug fever
by end of first seizures disorder withdrawal: symptoms on abrupt
week to 50mg bid- discontinuation of prolonged therapy,
tid nausea, headache, vertigo, nightmares,
Route: malaise
PO others: nasal congestion, excessive
appetite, weight gain or loss, sweating
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Bacteriosta Systemic o Contraindicated with CNS: headache, mild depression,  Monitor hematologic data
chloramphenicol tic effect o Serious allergy to mental confusion, delirium carefully, especially with
Brand Name: against infections for chloramphenicol GI: Nausea, vomiting, glossitis, long term therapy by any
chloramycetin susceptible which no other o Use cautiously with stomatitis, diarrhea route of administration
Classification: bacteria, antibiotic is renal failure, G6PD Hematologic: blood dyscrasias serious and fatal blood
antibiotic prevents effective deficiency, others: fever, macular rashes, dyscracias have occurred
Dosage: cell o Acute infections intermittent urticarial, anaphylaxis, gray baby  Culture infection before
Adults: replication. caused by porphyria, syndrome, superinfections beginning therapy
50mg/kg/day IV in salmonella pregnancy OPTHALMIC  Do not give IM because it is
divided every 6hr haemophilus Hematologic: bone marrow ineffective
up to 100mg/kg/day influenza, hypoplasia and plastic anemia with  Reduce dosage in patients
in severe cases rickettsiae, prolonged or frequent intermittent with renal or hepatic
Pediatric patients: lymphogranulo ocular used disease
50-75mg/kg/day IV ma- psittacosis Hypersensitivity: irritation,  Monitor serum levels
in divided doses group burning, itching, angioneurotic periodically as indicated in
every 6hr o Cystic fibrosis edema, urticarial, dermatitis dosage section.
 Meningitis: 50- regimen Other: superinfections  Change to another
100mg/kg/day Ophthalmic antibiotics as soon as
in divided dose o Treatment of possible
every 6hr superficial
 Neonates: less ocular
than 2kg and or infections
younger than 7 caused by
days 25mg/kg susceptible
daily microorganisms
 Older than 7 for which less
days and more dangerous
than 2kg: drugs are
50mg/kg/day in ineffective or
divided doses contraindicated
every 12hrs
Route:
IV
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Bacteriosta Systemic o Contraindicate CNS: reversible hearing loss,  Culture site of infection
erythromycin tic or administrations d with allergy confusion, uncontrollable emotions, before therapy
Brand Name: bactericidal o Acute infections to abnormal thinking  Administer oral
Erythromycin in caused by sensitive erythromycin CV: ventricular arrhythmias erythromycin base or
estolate, susceptible strains of o Use cautiously GI: abdominal cramping, anorexia, stearate on an empty
erythromycin ethyl bacteria, streptococcus with hepatic diarrhea, vomiting, hepatoxicity, stomach, 1 hr. before or 2-
succinate, binds to pneumonia, impairment, pseudomembranous colitis 3hr after meals, with a full
erythromycin cell mycoplasma lactation Hypersensitivity: allergic glass of water
lactobionate membrane, pneumonia, listeria reactions ranging from rash to  Administer around the clock
Classification: causing monocytogenes, anaphylaxis to maximize effect, adjust
Macrolide antibiotic change in legionella Other: superinfections schedule to minimize sleep
Dosage: protein pneumophilia disruption
Adults: 15- function, o URIs lower  Monitor liver function in
20mg/kg/day in leading to respiratory tract patient on prolonged
divided doses cell death infections, skin and therapy
every 6hr soft tissue infections  Give some preparations
Pediatric patients: caused by Group A with meals, as directed or
30-50 mg/kg/day beta hemolytic substitute one of these
PO in divided streptococci when preparations, if GI upset
doses oral treatment is occurs with oral therapy
preferred to
injectable benzathine
penicillin
o PID caused by N.
gonorrhoeae in
patients allergic to
penicillin
o In conjunction with
sulfonamides in URIs
caused by
haemophilus
influenzae
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name: Bacteriosta Systemic o Contraindicate CNS: headache, mild depression,  Monitor hematologic data
chloramphenicol tic effect  Serious infections for d with allergy mental confusion, delirium carefully, especially with
Brand Name: against which no other to GI: nausea, vomiting, glossitis, long term therapy by any
chloromycin susceptible antibiotic is effective. chloramphenic stomatitis, diarrhea route of administration
Classification: bacteria;  Acute infections ol Hematologic: blood dyscrasias serious and fatal blood
antibiotic prevents caused by salmonella o Use cautiously Other: fever, muscular rashes, dyscrasias have occurred.
Dosage: cell typhi with renal urticarial, anaphylaxis, gray baby  Reduce dosage in patients
Adults: 50- replication  Serious infections failure, hepatic syndrome, abdominal distention. with renal or hepatic
100mg/kg/day iv in caused by salmonella failure, g6pd disease
divided doses haemophilus deficiency,  Monitor serum levels
every 6hr influenzae, intermittent periodically as indicated in
Pediatric patients: rickettsiae, porphyria, dosage action
50-75 mg/kg/day IV lymphogranuloma pregnancy,  Change to another antibiotic
in divided doses  Cystic fibrosis lactation. as soon as possible
every 6hr. regimen
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name:  Inhibits RNA  Treatment of o Contraindicate CNS: headache, drowsiness,  Administer on empty
rifampin polymerase pulmonary TB d with allergy fatigue, dizziness, inability to stomach 1 hr. before or 2
Brand Name: activity in in conjunction to rifamycin, concentrate, mental confusion, hrs. after meal
Rifadin, rimactane susceptible with at least acute hepatic generalized numbness, ataxia,  Administer in a single day
Classification: bacteria cells one other disease, muscle weakness, visual dose
antibiotic, effective lactation disturbances  Consult pharmacist for
antituberculotic antituberculotic o Use cautiously Dermatologic: Rash, pruritus, rifampin suspension for
Dosage:  Neisseria with pregnancy urticarial, pemphigoid reaction, patients unable to swallow
Adults: 10 meningitides flushing, reddish orange capsules.
mg/kg/day; not carriers, for discoloration of body fluids  Prepare pt. for the reddish
exceed 600 mg in a asymptomatic GI: heartburn, epigastric distress, orange coloring of body
single daily dose carriers to anorexia, nausea, vomiting, gas, fluids
PO or IV eliminate cramps, diarrhea
meningococci GU: hemoglobinuria, hematuria,
from renal insufficiency, acute renal
nasopharynx; failure, menstrual disturbances
not for Hematologic: eosinophilia,
treatment of thrombocytopenia, transient
meningitis leukopenia, hemolytic anemia,
 Unlabeled decreased HGB, hemolysis
uses: Other: pain in extremities,
infections osteomalacia, myopathy, fever,
caused by flulike symptoms.
staphylococcu
s epidermis,
usually in
combination
therapy.
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility Rationale

Generic Name:  Alters effect  Schizophrenia o Hypersensitivit CNS: neuroleptic  Assess mental status  So that the nurse can
chlorpromazine of dopamine and psychosis. y to sulfites malignant syndrome, prior to and periodically determine major or minor
Brand Name: (D2) in CNS. Hyper (injectable) or sedation, during therapy. changes after drug has
Thorazine Has excitable, benzyl alcohol extrapyramidal  Monitor BP and pulse been taken.
Classification: significant explosive (SR capsules); reactions, TD prior to and frequently  To observe for any changes
antipsychotics anticholinergi behavior in cross EENT: Blurred vision, during the period of relevant.
antiemetics c/ alpha- children. sensitivity with dry eyes, lens dosage adjustment. May  May be taken w/ meals to
adrenergic Hyperactive other opacities
Dosage: cause QT interval reduce GI discomfort
blocking children with phenothiazine’ CV: Hypotension,
Usual: PO (Adults): changes on ECG.  To ensure that medication
activity conduct s may occur, tachycardia
Psychoses: 10-25mg angle closure GI: Constipation, dry  The drug may be taken is actually taken and not
disorder. Acute
2-4 times daily; mania, glaucoma, mouth, anorexia, with or without food. hoarded.
may ↑ every 3– nausea, bone marrow hepatitis, ileus,  Observe patient carefully  Assess patient for signs and
4days (usual dose is vomiting, depression, priapism when administering symptoms of dehydration.
200mg/day; up to intractable severe liver/CV GU: Urinary retention medication.  to be able to watch out for
1g/day) or 30-300mg hiccups, disease, DERM:  Monitor I&O ratios and any changes, and report to
1-3 times daily as preoperative concurrent Photosensitivity, daily weight. physician these changes
extended-release apprehension. pimozide use pigment changes,  Monitor for development
capsules. Acute rashes of neuroleptic malignant
IM (Adults): intermittent ENDO: Galacthorrea, syndrome (fever,
Severe psychosis:25- porphyria. amenorrhea respiratory distress,
50 mg initially, may  Off label use: HEMAT: tachycardia, seizures,
be repeated in vascular Agranulocytosis, diaphoresis,
1 hr; ↑ to headache, leukopenia hypertension or
maximum of 400mg bipolar METAB: hypotension, pallor,
disorder Hyperthermia
every 3-12 hr. tiredness, severe muscle
MISC: Allergic
if needed (up to stiffness, loss of bladder
reactions
1g/day). control. Report
symptoms immediately.
May also cause
leukocytosis, elevated
liver function tests
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name:  Competitively  Treatment of Hypersensitivity FREQUENT:  If pt. is having acute
diphenhydramine blocks effects allergic reactions (eczema, Drowsiness, dizziness, allergic reaction, obtain
Brand Name: of histamine reactions, pruritus, rash, cardiac muscle weakness, history of recently
Benadryl, Genahist, at peripheral parkinsonism; disturbances, hypotension, urinary ingested foods,
Sominex, Unisom H1receptor prevention/trea photosensitivity) may retention, thickening of drugs, environmental
Classification: sites. tment of occur. Overdose bronchial secretions, dry exposure, emotional
antihistamine nausea, symptoms may vary from mouth, nose, throat, stress. Monitor B/P, rate,
Dosage: vomiting, CNS depression lips; in elderly: sedation, depth, rhythm, type of
usual-50mg at vertigo due to (sedation, apnea, dizziness, hypotension. respiration; quality, rate
bedtime for sleep motion sickness; hypotension, OCCASIONAL: of pulse. Assess lung
aide Prescribed:25mg antitussive; cardiovascular collapse, Epigastric distress, sounds for rhonchi,
tablet nightly short-term death) to severe flushing, visual/hearing wheezing, rales.
Route: oral management of paradoxical disturbances, Patient teaching:
Onset: 15-30minutes insomnia. reactions(hallucinations, paresthesia,  Tolerance to
Peak: 1-4hrDuration: Topical form tremor, diaphoresis, chills. antihistaminic effect
4-6 hr. used for relief of seizures).Children, generally does not occur;
pruritus, insect infants, neonates may tolerance to sedative
bites, skin experience paradoxical effect may occur.
irritations. reactions(restlessness,  Avoid tasks that require
insomnia, euphoria, alertness, motor skills
nervousness, until response to drug is
tremors).Over dosage in established.
children may resulting  Dry mouth, drowsiness,
hallucinations, seizures, dizziness may be an
death expected response of
drug.
 Avoid alcohol.
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic Name:  Second-  Pharyngitis,  Contraindicated Body as a Whole:  Determine history
CEFUROXIME generation tonsillitis, in patients Thrombophlebitis (IV of hypersensitivity
Brand Name: cephalosporin infections of the hypersensitive to site); pain, burning, reactions to
ZOLTAX that inhibits urinary and drug. cellulitis (IM site); cephalosporin’s,
Classification: cell-wall lower  Use cautiously in superinfections, positive penicillin’s and history of
ANTIBIOTIC synthesis, respiratory patients Coombs'test. allergies particularly to
Frequency: promoting tracts, and skin hypersensitive to GI: Diarrhea, nausea, drugs before therapy is
BID osmotic and skin- penicillin antibiotic-associated initiated.
Dosage: instability; structure because of colitis.  Report onset of loose
1 tab 500 mg usually infections possibility of Skin: Rash, pruritus, stools
Route: bactericidal. caused by cross-sensitivity urticaria.  Absorption of cefuroxime
PO Streptococcus with other beta- Urogenital: Increased is enhanced by food.
pneumonia and lactam serum cretonne and  Notify prescriber about
S. pyogenes, antibiotics. BUN, decreased rashes or superinfections
Haemophilus  Use with caution creatinine clearance
influenzae, in breast-feeding
Staphylococcus women and
aureus, inpatients with
Escherichia coli. history of colitis
or renal
sufficiency.
 MISSION
“MABINI COLLEGES provides quality instruction, research and
MABINI COLLEGES, INC. extension service programs at all educational levels as its
VISION
“MABINI COLLEGES shall cultivate a CULTURE
College of Nursing and Midwifery monumental contribution to national and global growth and
development.
Specifically, it transforms students into:
of EXCELLENCE in education.” Daet Camarines Norte 1. God – fearing
2. Nation – loving
3. Law abiding
4. Earth caring
5. Productive, and
6. Locally and Globally competitive persons

Drug Action Indication Contraindication Adverse Effects Nursing Responsibility

Generic:  Alters the  Acute and  Hypersensitivity; cro CNS:  Assess patient’s mental
Fluphenazine effects chronic ss-sensitivity with NEUROLEPTIC MALIGNANT status (orientation, mood,
BRAND: of dopamine psychosis other SYNDROME, behavior) before and
Prolixin, in CNS. phenothiazines extrapyramidal reactions, periodically throughout
Fluphenazine Anticholinergi mayexist; sedation, therapy
Decanoate c and alpha- subcortical brain tardive dyskinesia.  Monitor blood pressure
adrenergic damage; severe CNS EENT: (sitting, standing, lying), ECG,
CLASSIFICATION: blocking depression; coma; Blurred vision, dry eyes. pulse, and respiratory rate
Antipsychotics activity. bone marrow CV: before and frequently during
DOSAGE: depression; Hypertension, hypotension, the period of dosage
Usual: PO (Adults): liverdisease; tachycardia. adjustment. May cause Q-
0.5-10 mg/day in hypersensitivity to GI: wave and T-wave changes in
divided doses every sesame oil Anorexia, constipation, ECG.
6-8 hr. (maximum (decanoate salt); drug-induced hepatitis, dry  Observe patient carefully
dose = 40 mg/day) some products mouth, ileus, nausea, when administering oral
contain alcohol or weight gain. medication to ensure that
IM (Adults): tartrazine and GU: medication is actually taken
12.5–25 mg initially; should be avoided in Urinary retention. and not hoarded
may be repeated clients with known Derm:  Assess fluid intake and bowel
every 3wk. Dosage intolerance; Photosensitivity, pigment function. Increased bulk and
may be concurrent use changes, rashes. fluids in the diet help
slowly ↑ as of drugs that Endo: minimize constipation\
needed (not to prolong QT interval Galactorrhea.  Monitor patient for onset
exceed 100mg/dose). Hemat: of akathisia (restlessness or
AGRANULOCYTOSIS, desire to keep moving) and
leukopenia, extrapyramidal side effects
thrombocytopenia. (parkinsonian)Difficulty
Misc: speaking or swallowing, loss
Allergic reactions. of balance control, pill rolling,
mask-like face.