Professional Documents
Culture Documents
Malrotation Perforation
Malrotation Perforation
Of
infants with meconium ileus, 80 to 90% have cystic fibrosis.
About 50% of cases are complicated by malrotation, intestinal atresia, or perforation. The distended
loops of small bowel may twist to form a volvulus in utero. If the intestine loses its vascular supply and
infarcts, sterile meconium peritonitis can result. The infarcted intestinal loop may be resorbed, leaving an
area or areas of intestinal atresia. Infants with meconium ileus are also at increased risk of
developing cholestasis.
Alagille syndrome
straight nose with a bulbous tip (9.1), but these features are
not very typical in early infancy. The parents may also have
cholinesterase).
globulins).
LDH
• Less specific
Alkaline phosphatase
sepsis, Budd–Chiari)
• Cholangitis
• Wilson’s disease
• Autoimmune hepatitis
• Wilson’s disease
• α-1-antitrypsin deficiency
• Autoimmune hepatitis
• Drug/alcohol-induced hepatitis
• Porphyrias
• Cystic fibrosis