Fibroadenoma.

The lesion consists of a proliferation

of intralobular stroma surrounding and often pushing
and distorting the associated epithelium. The border
is sharply delimited from the surrounding tissue.
fibroadenoma
 Comedo DCIS fills several adjacent ducts and is
characterized by large central zones of necrosis with
calcified debris.
Epithelial cell fill and elandular space expand the duct
forming glandular space(low grade)
High grade tumor due to polymorphic cells with central
necrosis
 Lobular carcinoma in situ. A monomorphic
population of small, rounded, loosely cohesive cells
fills and expands the acini of a lobule. The underlying
lobular architecture can still be recognized.
Pools of mucine in which nets of malignant cells are suspended
 Mucinous (colloid) carcinoma. The tumor cells are
present as small clusters within large pools of mucin.
The borders are typically well circumscribed, and
these cancers often mimic benign masses.
The margin of a cancer of the breast revealing
tumorous infiltration of the adjacent fatty tissue
(right).
Medullary carcinoma. The cells are highly pleomorphic with
frequent mitoses and grow as sheets of cohesive cells. A
lymphoplasmacytic infiltrate is prominent
Malignant epithelial cells with hyperchromatic
nuclei and pale cytoplasmin infiltrated areola
and nipples