Supplementary Figure

A Simple Desorption Atmospheric Pressure Chemical

Ionization Method for Enhanced Non-volatile Sample Analysis

Md. Matiur Rahman1, Ting Jiang1, Yang Tang 1 and Wei Xu1,2*

1Department of Biomedical Engineering, School of Life Science, Beijing Institute of

Technology, Beijing 100081, China

2State Key Laboratory Explosion Science and Technology, Beijing Institute of

Technology, Beijing 100081, China

*Corresponding Author:

Wei Xu

School of Life Science

Beijing Institute of Technology

Haidian, Beijing, 100081, China

Email: weixu@bit.edu.cn

Phone: +86-010-68918123

Keywords: Corona discharge, nonvolatile compound, biological sample

Figure S1. Impact of different maximum injection time on the ion intensity of m/z

20-200 and 50-200 for SDAPCI-MS of acetic acid

Figure S2. Comparison of different temperatures of the ion transport tube using 5 ng

RDX in acetonitrile a) 140 °C b) 180 °C c) 220 °C d) 260 °C.

Figure S3. Mass spectra for 5 ng explosives a) RDX b) 8701 c) C4 and d) TNT
Figure S4. The mass spectra for a) olive oil (50 ng), b) Escherichia coli c)&(e, octyl

β-D-glucopyranoside (50 ng). The MS/MS data for octyl β-D-glucopyranoside d) & f)
Figure S5. (a–f) Comparison of SDAPCI and DAPCI mass spectra for 2 mg/mL serine

(a&b), lysine (c&d) and valine (e&f) prepared in methanol. The high potential applied

to the needle was 1.3-1.5 kV (current: 20 nanoamp) for SDAPCI and 3.0-3.5 kV

(current: 2400 nanoamp) for DAPCI. The distance between the tip of the needle and

the cap of the inlet is 1 mm for SDAPCI and 5 mm for DAPCI.

Supplementary table S1: SDAPCI data, n = 3

Explosive Nominal concentration Accuracy (%) Precision

compounds µg/mL (RSD %)

0.5 98.2 0.42

RDX 5 99.7 4.24

25 99.8 0.21

0.5 99.5 0.17

C4 5 99.8 1.82

25 99.8 0.32

0.5 99.6 0.17

8701 5 99.8 0.20

25 99.8 0.39

0.5 99.0 1.19

TNT 5 99.3 19.28*

25 100.2 7.35

*Bold mark indicates that not meeting the requirements.