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Question 36 of 207

Which of the following statements relating the fluid physiology of a physiologically normal 70 Kg adult male is false?

He will have more water per unit of body weight than a female of
similar weight

Plasma will comprise 25% of his body weight

Interstitial fluid will account for up to 24% of body weight

Approximately 65% of total body water is intracellular

60% of his body weight is composed of water

The 60-40-20 rule:

60% total body weight is water
40% of total body weight is intracellular fluids
20% of body weight is extracellular fluids

Plasma typically accounts for 4-6% of body weight in healthy individuals.

Males typically have more water per unit weight than females, as females have a higher fat content.
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Fluid compartment physiology

Body fluid compartments comprise intracellular and extracellular compartments. The latter includes interstitial fluid, plasma and
transcellular fluid.
Typical figures are based on the 70 Kg male.

Body fluid volumes

Compartment Volume in litres Percentage of total volume

Intracellular 28 L 60-65%

Extracellular 14 L 35-40%
Compartment Volume in litres Percentage of total volume

Plasma 3L 5%

Interstitial 10 L 24%

Transcellular 1L 3%

Figures are approximate

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