Rotavirus - Adenovirus

Astrovirus - Norovirus

Rotavirus, Adenovirus and Astrovirus are the

agents most frequently responsible for gas-
troenteritis in infant and youth populations, as
well as occasionally in adults. They are trans-
mitted faeco-orally and their main symptoms
are watery diarrhoea and vomiting.

The concern for global public health cau-

sed by Noroviruses has increased in recent
years due to sporadic outbreaNs of signiÀcant
morbidity and mortality. There are frequent
outbreaks in schools, hospitals, cruise ships
and other semi-closed institutions.

Noroviruses are the main cause of gastroenteritis epidemics in the United States (approximately 90% of outbreaks
of non-bacterial gastroenteritis). The symptoms associated with Novovirus infections are typical of gastroenteritis: vomiting,
watery diarrhoea and abdominal cramps.

Enteric viruses have been recognised as the most important aetiological agents behind acute diarrhoea, the principal
cause of mortality in many countries. SpeciÀcally, the four categories of viruses considered to be the most clinically relevant
are the Group A Rotavirus, Adenovirus, Astrovirus and Norovirus. They give rise to co-infections in 46% of children with acute
diarrhoea.

The new CERTEST combined test for Rotavirus, Adenovirus, Astrovirus and Norovirus means the four main enteric vi-
ruses causing non-bacterial gastroenteritis can be simultaneously detected in stool samples using just a single test which is
both rapid and accurate.

folleto ingles rotavirus -adenovirus- astrovirus.indd 1 14/07/2014 20:50:55

 Test procedure

Cut the end of the cap and

 dispense exactly 4 drops into
the “A” circular window
marked with an arrow.

Unscrew the cap Close the tube with the diluent

step and use the stick and stool sample. Shake the
step step
1 to pick up 2 tube in order to assure good 3
the sample. sample dispersion.


Wait for coloured bands to Dispense exactly 4 drops into

step
appear. the “D” circular window
7 step
Read the result at 10 minutes marked with an arrow. 4

step Dispense exactly 4 drops into

6 the “B” circular window
marked with an arrow.

10 min.

step
 5


Dispense exactly 4 drops into

the “C” circular window
marked with an arrow.

Interpretation of the results

 
  
 

  
  
  

 
  
  

     
      
      



 
 

  
  
  

 
  
 

    
     
     


SENSITIVITY SPECIFICITY PPV NPV

Rotavirus >99% 98% >94% >99%
Adenovirus >99% >99% >99% >99%
Astrovirus >94% >99% >99% >92%
Norovirus >99% >99% >99% >99%
FRG86EN

Pol. Ind. Río Gállego II oCalle J o Nº 1

50840 o San Mateo de Gállego o Zaragoza o Spain
Tel.: +34 976 520 354
www.certest.es
folleto ingles rotavirus -adenovirus- astrovirus.indd 2 14/07/2014 20:51:08