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Drug Metabolism (Tugas Translite)
Drug Metabolism (Tugas Translite)
In theory, if two drugs that can bind to the same sites on human serum
albumin are given together, they will compete for those sites. Thus, if a
patient taking warfarin is given a non – steroidal anti-inflammatory drug
such as indomethacin the non –steroid anti-infalmmatory drug will tend
to displace warfarin from its binding sites to form a new equilibrium. This
type of interaction is discussed in more detail on page 7.12
Drug metabolism