A patient require ceftriaxone 180 mg.

You have
a 2 ml syringe with 10 divisions per ml. The vial
contains 500 mg/5ml of ceftriaxone. How many
divisions in the 2 ml syringe will you fill to give
180 mg ceftriaxone?
A. 18
B. 1.8
C. 20
D. 2

Ans. A 18
Ref. See below
500 mg/5ml means every 100 mg is present in 1 ml,
So 180 mg will be present in 1.8 ml
10 divisions per ml means 0.1 ml per division
So, 1.8 ml will be present in 18 divisons
A patient presented with acute exacerbation of bronchial
asthma. Salbutamol inhalation didn’t improve the
condition of the patient. So, intravenous corticosteroids
and aminophylline were added and the condition
improved. What is the mechanism of action of
corticosteroids in this condition?

A. They cause bronchodilation when given with xanthines

B. They increase bronchial responsiveness to salbutamol
C. They increase the action of aminophylline on adenosine
receptors.
D. They increase the mucociliary clearance

Ans. B.
Ref:
Mechanism of action of vancomycin
is
A. Cell wall synthesis inhibition
B. Protein synthesis inhibition
C. Increase membrane permeability
D. Inhibit folic acid metabolism

Ans. A. Cell wall synthesis inhibition

Ref: Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 366
All of the following drugs are used in
emergency management of acute
hyperkalemia except
A. Calcium gluconate
B. Salbutamol
C. Glucose-Insulin
D. Intravenous magnesium sulphate
Ans. D. Intravenous magnesium sulphate
Ref: Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 545
Atropine is indicated in all the
following poisonings except
A. Baygon
B. Tik 20
C. Parathion
D. Endrin
Ans. D. Endrin
Ref:Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 42
A patient of septic shock was given
intravenous nor-epinephrine. The
response to this drug is best checked by
A. Increase in heart rate
B. Decrease in heart rate
C. Increase in mean arterial pressure
D. Decreased renal perfusion and reduced
urine output

Ans. C. Increase in mean arterial pressure

Ref: CMDT 2017/496
A diabetic and hypertensive patient taking
several drugs presented with septicemia.
Serum creatinine levels are 5.7 mg/dl.
Which of the following drug should be
stopped?
A. Insulin
B. Metoprolol
C. Linagliptin
D. Metformin
Ans D. Metformin
Ref:Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 176
A diabetic patient presented with uncontrolled
blood sugar level. He has history of pancreatitis
and family history of urinary bladder carcinoma.
He is allergic to sulfonylureas and do not want to
take injectable drugs. Which of the following
drug can be added to control his blood sugar?
A. Liraglutide
B. Sitagliptin
C. Canagliflozin
D. Glipizide

Ans. C. Canagliflozin
Ref:Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 177
Liraglutide is given subcutanously, sitagliptin can cause
pancreatitis and glipizide is a sulfonylurea
Which of the following drug can
decrease the size of prostate?
A. Tamsulosin
B. Sildenafil
C. Finasteride
D. Prazosin

Ans C. Finasteride
Ref: Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 187
Alpha blockers like tamsulosin and prazosin are for
symptomatic relief whereas finasteride decrease size of
prostate
A 27 year old female presented to
OPD of infertility clinic. She was
prescribed bromocriptine. What
could be the possible reason?
A. Hyperprolactinemia
B. Polycystic ovarian disease
C. Hypogonadotropic hypogonadism
D. Pelvic inflammatory disease
Ans. A. Hyperprolactinemia
Ref: Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 170
A young male developed 5 episodes of
loose stool 2 hours after eating in a
restaurant. He is afebrile and has mild
dehydration. What should be the
treatment?
A. Ciprofloxacin and Tinidazole
B. Only ciprofloxacin
C. Only ORS
D. Ciprofloxacin, tinidazole and ORS
Ans. c. Only ORS
Ref:Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 351
A patient presented with pain in the right lower
quadrant of abdomen. He has history of renal
stones in right kidney. He was prescribed an
opioid which is partial agonist at mu receptors
and antagonist at kappa receptors. The likely
drug given was
A. Pentazocine
B. Buprenorphine
C. Tramadol
D. Fentanyl
Ans. B. Buprenorphine
Ref: Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 237
A person has to go to Shimla next
morning. Treatment for motion sickness is
A. Scopolamine patch a night before
B. Ranitidine one night before and then
before the trip
C. Dimenhydrinate 1 hour before journey
D. Omeprazole half hour before trip

Ans. A.
Ref: Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 348
A female in labour ward was
administered opioid analgesic.
Which of the following drugs should
be kept ready for emergency?
A. Lignocaine
B. Naloxone
C. Diphenhydramine
D. Fentanyl
Ans B. Naloxone
Ref: Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 238
A patient on antitubercular drug therapy
developed tingling sensation on lower
limb. Which of the following drug should
be used for the treatment?
A. Thiamine
B. Folic acid
C. Pyridoxine
D. Vitamin B-12

Ans C. Pyridoxine
Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 411
Which of the following is an example
of placebo?
A. Herbal medication with no known
effect
B. Physiotherapy
C. Sham surgery
D. Cognitive Behavioural therapy
Ans C. Sham surgery
An unknown drug is being tested in experimental
set-up. The results obtained are given in table.
From these actions, new drug is likely to be
A. Beta 1 and beta 2 agonist
B. Alpha 1 antagonist and Beta 2 Agonist
C. M2 and M3 agonist
D. Alpha 1 and Beta 1 agonist
Parameter Placebo treated New drug treated
Heart Rate 72 86
Systolic BP 110 150
Diastolic BP 80 68
Tremors Absent Present

Ans. A. Beta 1 and Beta 2 agonist

Ref: See Below
Beta 1 stimulation increase heart rate and systolic BP
Beta 2 stimulation cause vasodilation and thus decrease in diastolic BP and tremors
Which of the following instructions should
be given to a lactating mother regarding
drug usage?
A. No advice is required as most of the
drugs are secreted negligibly in the milk.
B. Take drugs with longer half life
C. Tell her to feed the baby just before
next dose
D.?
Ans. C
Treatment of choice for anaphylactic
shock is
A. Adrenaline 0.5 ml of 1:1000
solution by intramuscular route
B. Adrenaline 1 ml of 1:10000 by
intravenous route
C. Atropine 3 mg intravenously
D. Adenosine 12 mg intravenously
Ans. A
Ref: Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 47
Drug of choice for scrub typhus
is
A. Azithromycin
B. Ciprofloxacin
C. Doxycycline
D. Chloramphenicol
Ans. C. Doxycycline
Ref:Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 381
Treatment of choice for a patient
with gonococcal as well as non-
gonococcal urethritis is
A. Ceftriaxone 250 mg im single dose
B. Cefixime 400 mg oral single dose
C. Ciprofloxacin 500 mg oral single
dose
D. Azithromycin 2 g oral single dose
Ans D. Azithromycin
Ref: Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 382
A patient of prinzmetal’s angina is started on
isosorbide mononitrate. What is the
mechanism of action of nitrates in this
condition?
A. Reduced cardiac contractility
B. Increased left ventricular end diastolic
volume
C. Decreased diastolic perfusion pressure
D. Endothelium independent coronary
vasodilation
Ans. D.
Ref:Review of Pharmacology by Gobind Rai Garg and Sparsh
Gupta 11th edition/page 117