Chemotherapy drugs used for nasal cavity and paranasal

sinus cancer
Chemotherapy drugs used to treat nasal cavity and paranasal sinus cancer are:

 cisplatin (Platinol AQ)

 carboplatin (Paraplatin, Paraplatin AQ)
 5-fluorouracil (Adrucil, 5-FU)
 docetaxel (Taxotere)
 paclitaxel (Taxol)
 gemcitabine (Gemzar)
 bleomycin (Blenoxane)
 cyclophosphamide (Cytoxan, Procytox)
 vinblastine (Velbe)
 methotrexate

The most common chemotherapy combinations used to treat nasal cavity and paranasal sinus
cancer are:

 etoposide (Vepesid, VP-16) and cisplatin

 etoposide and carboplatin
 cisplatin and 5-FU
 carboplatin and 5-FU
 cisplatin and paclitaxel
 cisplatin and cetuximab (Erbitux), which is a targeted therapy drug

Chemotherapy for nasal cavity and paranasal sinus cancers usually takes about 6 months to
complete. The drugs are usually given once every 3 or 4 weeks. Each 3- or 4- week period of
time is called a cycle. You will likely have 3 or 4 cycles of chemotherapy, and then your
healthcare team will do some tests to see if the treatment is working. If it is working, you may
have up to 6 cycles of treatment (as long as your side effects are not too severe).

ancer of the nasal cavity and paranasal sinus: radiation therapy and chemotherapy management.
Harrison LB, Sessions RB, & Kies MS. (2014). Head and Neck Cancer: A Multidisciplinary Approach. (4th
Edition). Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins. 21: 560-587.

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