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Viral Hepatitis Etiology and Mode of Transmission Pathogenesis Clinical Manifestations Diagnosis Treatment and Prevention Hepatitis A
Viral Hepatitis Etiology and Mode of Transmission Pathogenesis Clinical Manifestations Diagnosis Treatment and Prevention Hepatitis A
Viral Hepatitis Etiology and Mode of Pathogenesis Clinical manifestations Diagnosis Treatment and
Transmission Prevention
HEPATITIS A Single stranded RNA Incubates and Fever(83%) Serological testing Generally
virus, family replicates(viremia) inside Malaise -IgM anti-HAV Supportive
picornaviridae hepatocytes for 15-60 days . Anorexia
Virus is excreted into the bile Nausea Washing of hands
Oro- fecal route and into the intestine. Vomiting(80%) before handling
-Virus is shed into stools of Abdominal pain(43%) food and
Sexual route( oro-anal infected persons. Dark urine beverages
sexual contact) -Infectivity occurs before onset Jaundice(96%)
of symptoms and declines after -Self limiting condition Anti HAV
jaundice appears. vaccination
HEPATITIS C - SS RNA virus of Chronic evolution is due to an *Asymptomatic Serological testing Supportive
family unsuccessful cellular, humoral, *Acute Hepatitis - Anti HCV treatment
Flaviviridae and cytokine immune response, -Jaundice detection in
-Blood transfusions which results in an attack on the -Fever serum Administration of
- Exposure to infected hepatocytes. -Diarrhea - HCV RNA Interferon-alpha
contaminated body An imbalance in T- Helper cells -Loss of appetite determination
fluids type 1and Type 2 cytokines -Pruritus - Ribavirin
-Vertical Transmission * Chronic Hepatitis
* Liver cirrhosis Careful handling
of contaminated
specimens
Screening of
blood products
Avoidance of
used needles