Understanding Naltrexone

A safe, effective medication for the treatment of Alcohol Use Disorder

What is Naltrexone?
Naltrexone is a prescription medication approved by the FDA for the treatment of
Alcohol Use Disorder.

You can read more about Naltrexone in this patient information sheet prepared by the
National Institute on Alcohol Abuse and Alcoholism.

Is Naltrexone effective?
Yes. Numerous randomized controlled studies have shown that Naltrexone use is
associated with fewer cravings, fewer days drinking, fewer drinks per day, and fewer
relapses.

You can read more about the evidence for Naltrexone’s efficacy in this clinical update
published in the Addiction Treatment Forum.

How does Naltrexone work?

Naltrexone is an opioid antagonist. It binds to opioid receptors in the brain and blocks
feelings of euphoria and intoxication typically associated with alcohol consumption. This
helps break the destructive cycle in which one drink leads to another, enabling patients
to regain control of their drinking without relying upon willpower alone.

You can read more about how Naltrexone works in this overview published by the FDA.
(Please note that this document refers to Naltrexone by its brand name, Revia.)

Is Naltrexone addictive? What are the side effects?

Naltrexone is not addictive. Side effects are rare. Nausea and headache are the most
common, each of which affected less than 10% of study participants.

Do I need to quit drinking to use Naltrexone?

No. Naltrexone does not react adversely with alcohol, so it is safe to drink in moderation
while using Naltrexone. Some patients use Naltrexone to help them quit drinking while
others use it to help them cut back.

How often will I take Naltrexone?

Some patients take Naltrexone every day. Others take it only before drinking, using the
Sinclair Method. Long-term treatment of at least 3 months is considered most effective.

You can read more about the Sinclair Method at the website of the C Three Foundation.

Is Naltrexone right for me?

Only a healthcare professional can help you decide if Naltrexone is right for you. You
should ask your doctor about Naltrexone. Or, if you would like to connect with a doctor
who has experience prescribing Naltrexone to treat Alcohol Use Disorder and is
licensed in your state, please visit www.takecontrol.co and click on “Get Started.”

About Control
CONTROL 1
Control provides people who are ready to to control their drinking with with access to safe and
effective medication. To learn more and connect with a doctor, please visit www.takecontrol.co