PHINMA UNIVERSITY OF PANGASINAN

COLLEGE OF HEALTH SCIENCES

Nursing Department

DRUG STUDY
DRUG
DRUG INDICATION ACTION CONTRAINDICATION ADVERSE EFFECT NURSING CONSIDERATION
INTERACTION
Generic Name: >Susceptible >direct-acting >Cemitidine: may >contraindicated in >CNS: fever, >monitor liver function tests
metronidazole anaerobic infections, Trichomonacide increase risk of patients hypersensitivity vertigo, headache, carefully in elderly patients.
including and amebecide metronidazole toxicity to drug or other nitro ataxia, dizziness, >Give oral forms of meals.
intraabdominal, skin that works inside because of inhibited imidazole derivatives and syncope, >Observe patients with edema,
and skin structures, and outside the hepatic metabolism. in patients in first trimester incoordination, especially if he’s receiving
gynecologic, intestines. It’s Monitor patient for of pregnancy. confusion, irritability, corticosteroids. Flagyl IV RDU may
bacterial septicemia, thought to enter the toxicity. > use cautiously in depression, cause sodium retention.
Brand Name: bone and joint, CNS, cells of >Disulfiram: may patients with history of weakness, >record number and characters
lower respiratory microorganisms that cause acute psychosis bloody dyscrasia, CNS insomnia, seizures, of stools
Flagyl tract, endocarditis. contain and confusion. disorder, or retinal or peripheral when drug is used to treat
nitroreductase, Avoiding giving visual field changes. neuropathy. amebiasis.
forming unstable metronidazole within 2 > Use cautiously in >CV: flattened T >Give drug only after
compounds that weeks of disulfiram. patients who take wave, edema, Trichonomaas vaginalis infection
Drug bind to DNA and >Lithium: may hepatoxic drugs or have flushing, is confirmed by wet smear culture
inhibit synthesis, increase lithium level, hepatic disease or thrombophlebitis or entameba histolyca is
Classification: causing cell death. which may cause alcoholism. after IV infusion. identified.
Pregnancy risk toxicity. Monitor lithium >EENT: rhinitis, >Sexual partners of patients being
category B level. sinusitis, pharyngitis. treated for T. vaginalis infection,
>GI: abdominal even if asymptomatic, must be
cramping or pain, treated to avoid reinfection.
stomatitis,
epigastric pain,
N/V, anorexia,
diarrhea,
constipation,
proctitis, dry mouth,
metallic taste.

SUBMITTED BY: Giselle Chloe B. Ico