Name of Drug Mechanism

Memantine
(Namenda)
10mg P.O.
BID Binds to CNS N-methyl-D-aspartate (NMDA)
receptor sites, preventing binding of glutamate,
an excitatory neurotransmitter
Classification:
anti-Alzheimer's agent

Vigocid
(Piperacillin/Tazobactam) Piperaceillin binds to bacterial cell wall membrane,
4.5 grms IV infusion causing cell death. Spectrum is extended
8hrs ANST for 2days compared with other penicillins. Tazobactam
inihibits beta-lactamase, an enzyme that can
Classification: destroy penicillins.
anti-infectives

Rivastagmine
(Exelon Patch) Enhances cholinergic function by reversible
OD inhibition of cholinesterase.
Does not cure the disease.
Classification:
anti-Alzheimer's agents
 Indication
Decreased symptoms of dementia.
Does not slow progression.
Cognitive enhancement.
Does not cure disease
Community-acquired and nocosomial
pneumonia caused by piperacillin-
resistant, beta-lactamase - producing
bacteria.
Decreased dementia (temporary)
associated with Alzheimer's disease and Use cautiously with patient with history of
Parkinson's disease.
Enhanced cognitive ability.
Contraindication
Contraindicated to patient with severe
renal impairement
Use cautiously in patient with moderate
renal impairement; Concurrent use of
other NMDA antagonists (amantadine,
rimantandine, ketamine,
dextromethorphan); Concurrent use of
drugs or diet that cause alkaline urine;
Condition that increase urine pH including
severe urinary tract infections or renal
tubular acidosis.
Contraindicated to patient with
hypersensitivity to penicillins, beta-
lactams, cephalosporins or tazobactam.
Use cautiously to patient with renal
impairement; sodium restriction
Contraindicated to patient with
hypersensitivity to revastigmine or other
carbamates.
asthma or obstructive pulmory disease;
history of GI bleeding; Sick sinus syndrome
or other supraventricular cardiac
conduction abnormalities.
 Adverse Effects

Dizziness, fatigue, headache, sedation

Hypertension
Rash
Weight gain
Urinary frequenncy
Anemia

Seizure; confusion, dizziness, headache,

insomia, lethargy
Pseudomembranous colitis, diarrhea,
constipation; druginduced hepatitis, nausea,
vomiting, interstitial nephritis
Rashes, ucticaria
Bleeding, leukopenia, neutropenia,
thromobocytopenia

Weakness, dizziness, drowsiness headache,

sedation (unusual)
Edema, heart failure; hypotension
Anorexia; dyspepsia, nausea, vomiting,
abdominal pain, diarrhea, flatulence
Tremors
Nursing Responsibilities

1. 5 Drug Rights
2. Assess cognitive function