Scribd Logo
Upload

Welcome to Scribd!

  • 3 views

    Antibiotics

    Uploaded by

    Hashim
    Antibiotics are chemical substances that kill or inhibit the growth of bacteria. There are natural, synthetic, and semi-synthetic antibiotics. Antibiotics can be bactericidal, killing bacteria, or bacteriostatic, inhibiting bacterial growth. A good antibiotic kills or inhibits bacteria at low concentrations, has a broad spectrum of effectiveness, and has minimal side effects and appropriate pharmacokinetic properties to reach the infection site. Antibiotics are important as they cure acute infections, previously incurable infections, are used for surgical prophylaxis and treatment, and enable cancer chemotherapy by temporarily destroying neutrophils.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content

    You might also like

    Antibiotics

    Uploaded by

    Hashim
    3 views1 page
    Antibiotics are chemical substances that kill or inhibit the growth of bacteria. There are natural, synthetic, and semi-synthetic antibiotics. Antibiotics can be bactericidal, killing bacteria, or bacteriostatic, inhibiting bacterial growth. A good antibiotic kills or inhibits bacteria at low concentrations, has a broad spectrum of effectiveness, and has minimal side effects and appropriate pharmacokinetic properties to reach the infection site. Antibiotics are important as they cure acute infections, previously incurable infections, are used for surgical prophylaxis and treatment, and enable cancer chemotherapy by temporarily destroying neutrophils.

    Original Description:

    antibiotics

    Original Title

    antibiotics

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Antibiotics are chemical substances that kill or inhibit the growth of bacteria. There are natural, synthetic, and semi-synthetic antibiotics. Antibiotics can be bactericidal, killing bacteria, or bacteriostatic, inhibiting bacterial growth. A good antibiotic kills or inhibits bacteria at low concentrations, has a broad spectrum of effectiveness, and has minimal side effects and appropriate pharmacokinetic properties to reach the infection site. Antibiotics are important as they cure acute infections, previously incurable infections, are used for surgical prophylaxis and treatment, and enable cancer chemotherapy by temporarily destroying neutrophils.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    3 views1 page

    Antibiotics

    Uploaded by

    Hashim
    Antibiotics are chemical substances that kill or inhibit the growth of bacteria. There are natural, synthetic, and semi-synthetic antibiotics. Antibiotics can be bactericidal, killing bacteria, or bacteriostatic, inhibiting bacterial growth. A good antibiotic kills or inhibits bacteria at low concentrations, has a broad spectrum of effectiveness, and has minimal side effects and appropriate pharmacokinetic properties to reach the infection site. Antibiotics are important as they cure acute infections, previously incurable infections, are used for surgical prophylaxis and treatment, and enable cancer chemotherapy by temporarily destroying neutrophils.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    of 1

    Unit 5: Antibiotics

    Antibiotics
    Chemical substances that kill or inhibit the growth of bacteria

    Types of antibiotics
    n Natural products (from bacteria, fungi)
    n Synthetic (from chemists)
    n Semi-synthetic – natural products chemically modified in the laboratory

    Effects of antibiotics
    n Bactericidal (kill bacteria)
    n Bacteriostatic (inhibit growth but do not kill bacteria)

    Characteristics of a Good Antibiotic


    Kills or inhibits the growth of bacteria at low concentrations
    Broad spectrum
    e.g (Chloramphenicol)

    Minimal side effects


    n Due to direct effects of antibiotic itself
    n Due to effects on the normal microflora of the body

    Appropriate pharmacokinetic properties


    n Must get to the site of infection in high concentrations
    n Distribution influences mode of administration (oral, injected)

    Effects of antibiotics
    n Bactericidal (kill bacteria)
    n Bacteriostatic (inhibit growth but do not kill bacteria)

    Importance of antibiotics
    Cure acute infections, e.g., bacterial pneumonia
    Curing previously incurable infections, e.g., ulcers, others(?)
    Prophylaxis/treatment of surgical patients
    Cancer chemotherapy – destroys neutrophils temporarily

    Dr R Bholah, MIE

    PDF created with pdfFactory Pro trial version www.pdffactory.com

    You might also like