Organic Synthesis and Carbon-Carbon Bond Forming Reactions

1. To introduce basic concepts of organic synthesis:�

Retrosynthesis � thinking backwards from relatively complex molecules to simpler ones � the
disconnection approach.

2. To classify and extend the main carbon-carbon bond forming reactions (CCBFR) introduced
in CHE1C1Y.

3. To illustrate the importance of organic synthesis with real examples.

Organic Synthesis

Introduction

Why bother?!

Ca. 7 million organic compounds known � most have been made by synthesis rather than
isolated from nature.