Lehninger Principles of Biochemistry 4/e Errata

*Lists corrections made by reprint.

Corrections made in second printing

p. 107, fig. 3-30, caption, 2nd & 3rd lines: EF-Tu corrected to Hsp70; protein now plural

p. 214, fig 6-18, caption, 2nd column, 4th to last line: comma inserted between Ser195 and
in orange

p. 392, 2nd column, 3rd line: activity deleted; replaced with transport, which ends the
sentence

p. 447, box 12-2, fig. 5: 433 nm corrected to 380 nm

p. 529, 2nd line of text: glycolitic corrected to glycolytic

p. 581, 2nd column, last line of 1st paragraph: figure reference (Fig. 15-22c) inserted after
FBPase-1

p. 705, fig. 19-17: 2H+ and vertical arrow leading into III added in red

p. 736, fig. 19-52: leader from Appressed membranes is now shaped like a horizontal y
and points to the two membranes

p. 737, fig. 19-54c: 2x deleted from 2 x 2H+

p. 741, fig. 19-57:

*equation in the lumen corrected from 2H2O O2 + 4H+ to H2O ½O2 + 2H+
*middle label corrected from 2H+ to 4H+

p. 876, 2nd to last line of 1st paragraph: Herpes replaces AIDS

p. 877, fig. 22-50:

Step 2 product
*two blue arrows removed: 1) between N-C bond and N-C bond; 2) between
H-C bond and C
*three new blue arrows added: 1) between :B and H; 2) between C-H bond
and C-C bond; 3) between C-N bond and N
Step 3 product
*two blue arrows removed: 1) between :B and H; 2) between C-H bond and
C-C bond.
*replaced :B with HB
*deleted top H bonded to C in central ring
*single C-C bond corrected to double C=C bond
 *blue arrow added between double C=C bond and C-C bond
*H atom in pink screen bonded to C deleted
*in top right, N=C double bond corrected to N-C single bond
*blue arrow added from N to C in N-C single bond
*H atom in pink screen added in top right bonded to C
*blue arrow added from single bond between new pink screened H atom and
C to lower left C

p. 890, fig. 23-7, caption: dark pink now reads pink

p. 893, fig. 23-12: pink color removed from adipose tissue in the human body outline

p. 914, 1st column: last two lines of first paragraph deleted; now reads: ‘…increase the
conversion of glucose to acetyl-CoA, providing the starting material for fat
synthesis.’

p. 953, fig. 25-5 caption, last line: conclusion of caption now reads: ‘(see Fig. 26-1b).
<icon>Nucleotide Polymerization by DNA Polymerase’

p. 961, fig. 25-14 caption: media icon and DNA Synthesis added at the end of the caption

p. AS-19, Chapter 26, problem 4, third line: simply deleted

p. AS-19, Chapter 26, problem 5: 3’  5’ direction corrected to 5’  3’ direction.

Another sentence added at the end of the brief answers runs as follows: Polynucleotide
phosphorylase forms phosphodiester bonds, but differs in all other listed properties.

Corrections made in third printing

p. 43, end of chapter problem 12: labels for figures (b) and (c) have been transposed. The
label for (b) is now Methionine enkephalin, the brain’s own opiate; the label for (c) is
Phosphotidylcholine, a component of many membranes

p. 89, column 2: the final two sentences of the 1st full paragraph now read The addition
of certain salts in the right amount can selectively precipitate some proteins, while
others remain in solution. Ammonium sulfate ((NH2) 2SO4) is particularly effective,
and often used to salt out proteins.

p. 97, fig. 3-24: fifth element of A chain corrected from Gln to Glu

p. 99, fig. 3-26: label acetylation by iodoacetate corrected to carboxymethylation by

iodoacetate
p. 99, fig. 3-26: label Acetylated cysteine residues corrected to Carboxymethylated
cysteine residues

p. 178, fig. 5-23a: first CH3 on the right corrected to C H2

p. 500, fig. 13-7:  - on the top far right corrected to read  +

p. 511, table 13-7: ubiquinol + H2 corrected to ubiquinol

p. 537, fig. 14-11: in the last step the two entries, NAD+ and NADH + H+ have been
transposed: NADH + H+ now leads to NAD+

p. 667, fig. 18-11: the single bond between oxygen and carbon in bicarbonate is now a
double bond

p. 671, fig. 18-15: pink and blue screens in the figure itself, but not the legend, have been
switched: those that were blue are now pink and vice versa

p. 725, 1st column, 3rd to last line in 1st paragraph: wavelength corrected to frequency

p. 906, table 23-4: the upward pointing arrow next to Acetyl-CoA carboxylase corrected
to point downward

p. 906, 2nd column, third to last line: 24 hours corrected to 4 hours

p. 996, fig. 26-1: dNTP channel corrected to read NTP channel

p. 999, fig. 26-5: the –35 Region of rrnb P1 corrected from GTGTCA to TTGTCA

Corrections made in Fifth Printing

p. 279, fig. 8-11: in the top portion of the Thymine section of the figures, the arrows
extending out from 2.8 Å have been lengthened to reach the red lines now centering on N
and O (as opposed to H and O)

p. 282, photograph of Maurice Wilkins: caption now reads: Maurice Wilkins, 1916 –
2004

p. 339, Further Reading: reference to Brenner, s. (2004) Genes to Genomics, removed

p. 340, Further Reading: reference added to Koonin, E. V. (2005) Orthologs, paralogs,

and evolutionary genomics. Annu. Rev. Genet. 9, 309–452.
p. 349, fig. 10-7: O atom inserted between the leftmost H atom and the bond to the center
C atom. O atom to the right of the center C atom deleted. The middle portion of the
structure now looks like HO  2C  H instead of H  2C  OH

p. 552, unnumbered figure: ribose 5-phosphate epimerase changed to ribulose 5-

phosphate epimerase

p. 573, table 15-2: Keq for Hexokinase changed from 2 x 103 to 1 x 103

p. 686, Further Reading: reference to Kirsch, J. F. & Eliot, A. C. (2004) Pyridoxal

phosphate enzymes: mechanistic, structural and evolutionary considerations. Annu. Rev.
Biochem. 73, [in press]. changed to Kirsch, J. F. & Eliot, A. C. (2004) Pyridoxal
phosphate enzymes: mechanistic, structural and evolutionary considerations. Annu. Rev.
Biochem. 73, 383–415.

p. 761, fig. 20-13: ribose below the arrows between Xylulose 5-phosphate and Ribulose
5-phosphate corrected to ribulose

p. 788, fig. 21-1: center element of Malonyl-CoA changed from CH3 to CH2

p. 974, fig. 25-25: subscript font corrected to match other figures

p. I-16: index entry added, Franklin, Rosalind, 282, 282f, 303

p. I-16: index entry changed, Fructose, 238, 239s, 240, 241s

p. I-42: index entry added, Wilkins, Maurice, 282, 282f