Drug Information: Famotidine: Why Is This Medication Prescribed?

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Drug Information: Famotidine

fa moe' ti deen

Why is this medication prescribed?

Prescription famotidine is used to to treat ulcers (sores on the lining of the stomach or small intestine);
gastroesophageal reflux disease [GERD, a condition in which backward flow of acid from the stomach
causes heartburn and injury of the esophagus (tube that connects the mouth and stomach)]; and
conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome (tumors in
the pancreas or small intestine that cause increased production of stomach acid). Over-the-counter
famotidine is used to prevent and treat heartburn due to acid indigestion and sour stomach caused by
eating or drinking certain foods or drinks. Famotidine is in a class of medications called H 2 blockers. It
works by decreasing the amount of acid made in the stomach.

How should this medicine be used?

Prescription famotidine comes as a tablet and a suspension (liquid) to take by mouth. It is usually
taken once daily at bedtime or two to four times a day. Over-the-counter famotidine comes as a tablet,
a chewable tablet, and a capsule to take by mouth. It is usually taken once or twice a day. To prevent
symptoms, it is taken 15 to 60 minutes before eating foods or drinking drinks that may cause
heartburn. Follow the directions on your prescription or the package label carefully, and ask your
doctor or pharmacist to explain any part you do not understand. Take famotidine exactly as directed.
Do not take more or less of it or take it more often or for a longer time than prescribed by your doctor.

Shake the liquid well for 5 to 10 seconds before each use to mix the medicine evenly.

Swallow the tablets and capsules with a full glass of water.

Thoroughly chew the chewable tablets before swallowing them. Swallow the chewed tablet with a full
glass of water.

Do not take more than two tablets, capsules, or chewable tablets of over-the -counter famotidine in 24
hours and do not take over-the-counter famotidine for longer than 2 weeks unless your doctor tells you
that you should. If symptoms of heartburn, acid indigestion, or sour stomach last longer than 2 weeks,
stop taking over-the-counter famotidine and call your doctor.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking famotidine,

 tell your doctor and pharmacist if you are allergic to famotidine, cimetidine (Tagamet),
nizatidine (Axid), ranitidine (Zantac), or any other medications.
 tell your doctor and pharmacist what prescription and nonprescription medications, vitamins,
nutritional supplements, and herbal products you are taking. Be sure to mention any other
medications for heartburn. Do not take over-the-counter famotidine with any other prescription
or nonprescription medications for heartburn unless a doctor tells you that you should.
 tell your doctor if you have phenylketonuria (PKU, an inborn disease in which mental
retardation develops if a specific diet is not followed), and if you have or have ever had trouble
swallowing or kidney disease.
 tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you
become pregnant while taking famotidine, call your doctor.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

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If you forget a dose of prescription famotidine, take the missed dose as soon as you remember it.
However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing
schedule. Do not take a double dose to make up for a missed one.

Over-the-counter famotidine is usually taken as needed. If your doctor has told you to take over-the-
counter famotidine regularly, take the missed dose as soon as you remember it. However, if it is
almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not
take a double dose to make up for a missed one.

What side effects can this medication cause?

Famotidine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go
away:

 headache
 dizziness
 constipation
 diarrhea
 fussiness (in babies who take famotidine)

Some side effects can be serious. The following symptoms are uncommon, but if you experience any
of them call your doctor immediately:

 hives
 skin rash
 itching
 swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
 hoarseness
 difficulty breathing or swallowing

Famotidine may cause other side effects. Call your doctor if you have any unusual problems while
taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug
Administration's (FDA) MedWatch Adverse Event Reporting program online [at
http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at
room temperature and away from excess heat and moisture (not in the bathroom). Do not allow the
liquid to freeze. Throw away any medication that is outdated or no longer needed, and throw away
unused famotidine liquid after 30 days. Talk to your pharmacist about the proper disposal of your
medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has
collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling
your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-
counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary
supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a
hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

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 Pepcid®  Pepcid® AC Maximum  Pepcid® Premixed in Iso-
 Pepcid® AC Strength osmotic Sodium Chloride
 Pepcid® Complete Injection
 Pepcid® AC Gelcaps
 Pepcid® I.V.  Pepcid® RPD

Last Revised - 10/01/2004


Last Reviewed - 08/01/2007

Drug Information: Felodipine


246
(fe loe' di peen)

Why is this medication prescribed?

Felodipine is used to treat high blood pressure. It relaxes your blood vessels so your heart does not
have to pump as hard.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more
information.

How should this medicine be used?

Felodipine comes as a tablet to take by mouth. It is usually taken once a day. Do not crush, chew, or
divide felodipine tablets. Follow the directions on your prescription label carefully, and ask your doctor
or pharmacist to explain any part you do not understand. Take felodipine exactly as directed. Do not
take more or less of it or take it more often than prescribed by your doctor.

Felodipine controls high blood pressure but does not cure it. Continue to take felodipine even if you
feel well. Do not stop taking felodipine without talking to your doctor.

Other uses for this medicine

Felodipine is also used sometimes to treat Raynaud's syndrome and congestive heart failure. Talk to
your doctor about the possible risks of using this drug for your condition.

What special precautions should I follow?

Before taking felodipine,

 tell your doctor and pharmacist if you are allergic to felodipine or any other drugs.
 tell your doctor and pharmacist what prescription and nonprescription medications you are
taking, especially antiseizure medicines such as carbamazepine (Tegretol), phenytoin
(Dilantin), and phenobarbital; cimetidine (Tagamet); erythromycin (E.E.S., E-Mycin, others);
itraconazole (Sporanox); ketoconazole (Nizoral); ranitidine (Zantac); and vitamins.
 tell your doctor if you have or have ever had heart, liver, or kidney disease.
 tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you
become pregnant while taking felodipine, call your doctor.
 if you are having surgery, including dental surgery, tell your doctor or dentist that you take
felodipine.

What special dietary instructions should I follow?

Talk to your doctor about drinking grapefruit juice or eating grapefruit while taking felodipine.

Talk to your doctor before using salt substitutes containing potassium. If your doctor prescribes a low-
salt or low-sodium diet, follow these directions carefully.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip
the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for
a missed one.

What side effects can this medication cause?

Felodipine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go
away:

 headache
 flushing (feeling of warmth)
 dizziness or lightheadedness
 weakness
 fast heartbeat
 heartburn
 constipation

247
 enlargement of gum tissue around teeth

If you experience any of the following symptoms, call your doctor immediately:

 swelling of the face, eyes, lips, tongue, arms, or legs


 difficulty breathing or swallowing
 fainting
 rash

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug
Administration's (FDA) MedWatch Adverse Event Reporting program online [at
http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at
room temperature and away from excess heat and moisture (not in the bathroom). Throw away any
medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of
your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has
collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked
regularly to determine your response to felodipine.

Good dental hygiene decreases the chance and severity of gum swelling. Brush your teeth regularly
and schedule dental cleanings every 6 months.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about
refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-
counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary
supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a
hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

 Plendil

Last Revised - 01/01/2008


Last Reviewed - 08/01/2007

Drug Information: Ferrous Sulfate (Iron)

248
(fer' us)

IMPORTANT WARNING:

Accidental overdose of products containing iron is a leading cause of fatal poisoning in children under
the age of 6. Keep this product out of the reach of children. In case of an accidental overdose, call your
doctor or a poison control center immediately.

Why is this medication prescribed?

Ferrous sulfate provides the iron needed by the body to produce red blood cells. It is used to treat or
prevent iron-deficiency anemia, a condition that occurs when the body has too few red blood cells
because of pregnancy, poor diet, excess bleeding, or other medical problems.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more
information.

How should this medicine be used?

Ferrous sulfate comes in regular, coated, and extended-release (long-acting) tablets; regular and
extended-release capsules; and oral liquid (syrup, drops, and elixir). Ferrous sulfate usually is taken
three times a day between meals. Follow the directions on your prescription label carefully, and ask
your doctor or pharmacist to explain any part you do not understand. Take ferrous sulfate exactly as
directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Although symptoms of iron deficiency usually improve within a few days, you may have to take ferrous
sulfate for 6 months if you have severe iron deficiency.

This medication should be taken on an empty stomach, at least 1 hour before or 2 hours after eating.

Ferrous sulfate drops come with a special dropper for measuring the dose. Ask your pharmacist to
show you how to use it. The drops may be placed directly in the mouth or mixed with water or fruit
juice (not with milk).

Do not crush or chew regular, coated, or extended-release tablets, and do not open regular or
extended-release capsules; swallow them whole.

What special precautions should I follow?

Before taking ferrous sulfate,

 tell your doctor and pharmacist if you are allergic to ferrous sulfate, tartrazine (a yellow dye in
some processed foods and drugs), or any other drugs.
 tell your doctor and pharmacist what prescription and nonprescription medications you are
taking, especially chloramphenicol, cimetidine (Tagamet), levodopa (Larodopa, Sinemet),
methyldopa (Aldomet), penicillamine, and vitamins. If you also are taking cinoxacin (Cinobac),
ciprofloxacin (Cipro), demeclocycline, doxycycline, enoxacin (Penetrex), levofloxacin
(Levaquin), lomefloxacin (Maxaquin), methacycline, minocycline, nalidixic acid (NegGram),
norfloxacin (Noroxin), ofloxacin (Floxin), oxytetracycline, sparfloxacin (Zagam), or tetracycline,
take it 3 hours after or 2 hours before taking ferrous sulfate. Do not take antacids at the same
time as ferrous sulfate; take them as far apart as possible.
 tell your doctor if you have or have ever had ulcers, colitis, or intestinal disease.
 tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you
become pregnant while taking ferrous sulfate, call your doctor.

What special dietary instructions should I follow?

Fish, meat (especially liver), and fortified cereals and breads are good dietary sources of iron;
emphasize them in a well-balanced diet.

What should I do if I forget a dose?

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Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip
the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for
a missed one.

What side effects can this medication cause?

Ferrous sulfate may cause side effects. Your stools will turn dark; this effect is harmless. Your teeth
may stain from the liquid; mix each dose with water or fruit juice. You may clean your teeth once a
week by rubbing them with a small amount of baking soda.

Tell your doctor if either of these symptoms is severe or does not go away:

 constipation
 stomach upset

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug
Administration's (FDA) MedWatch Adverse Event Reporting program online [at
http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at
room temperature and away from excess heat and moisture (not in the bathroom). Throw away any
medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of
your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has
collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to
check your response to ferrous sulfate.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about
refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-
counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary
supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a
hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

 Feosol®  Ferrex®-150  Nephro-Fer®


 Feosol® Caplets  Fe-Tinic® 150  Niferex®
 Feostat®  Hemocyte®  Niferex® Elixir
 Feratab®  Hytinic®  Niferex®-150
 Fer-Gen-Sol® Drops  Icar® Pediatric
 Fergon®  Ircon®  Slow FE®

 Fer-In-Sol® Drops  Mol-Iron®

Brand name(s) of combination products:

250
 Ferro-DSS® Caplets® containing Ferrous  Ferrous Fumarate with DSS® Timed
Fumarate and Docusate Sodium Capsules containing Ferrous Fumarate
and Docusate Sodium
 Ferro-Sequels® containing Ferrous
Fumarate and Docusate Sodium

Last Revised - 04/01/2003


Last Reviewed - 08/01/2007

Drug Information: Fluconazole

251
(floo kon' na zole)

Why is this medication prescribed?

Fluconazole is used to treat fungal infections, including yeast infections of the vagina, mouth, throat,
esophagus (tube leading from the mouth to the stomach), abdomen (area between the chest and
waist), lungs, blood, and other organs. Fluconazole is also used to treat meningitis (infection of the
membranes covering the brain and spine) caused by fungus. Fluconazole is also used to prevent
yeast infections in patients who are likely to become infected because they are being treated with
chemotherapy or radiation therapy before a bone marrow transplant (replacement of unhealthy spongy
tissue inside the bones with healthy tissue). Fluconazole is in a class of antifungals called triazoles. It
works by slowing the growth of fungi that cause infection.

How should this medicine be used?

Fluconazole comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken once a
day. You may need to take only one dose of fluconazole, or you may need to take fluconazole for
several weeks or longer. The length of your treatment depends on your condition and on how well you
respond to fluconazole. Follow the directions on your prescription label carefully, and ask your doctor
or pharmacist to explain any part you do not understand. Take fluconazole exactly as directed. Do not
take more or less of it or take it more often than prescribed by your doctor.

Your doctor may tell you to take a double dose of fluconazole on the first day of your treatment. Follow
these directions carefully.

Shake the liquid well before each use to mix the medication evenly.

Continue to take fluconazole until your doctor tells you that you should stop, even if you feel better. Do
not stop taking fluconazole without talking to your doctor. If you stop taking fluconazole too soon, your
infection may come back after a short time.

Other uses for this medicine

Fluconazole is also sometimes used to treat serious fungal infections that begin in the lungs and can
spread through the body and fungal infections of the eye, prostate (a male reproductive organ), skin
and nails. Fluconazole is also sometimes used to prevent fungal infections in people who are likely to
become infected because they have human immunodeficiency virus (HIV) or cancer or have had a
transplant operation (surgery to remove an organ and replace it with a donor or artificial organ). Talk to
your doctor about the possible risks of using this drug for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking fluconazole,

 tell your doctor and pharmacist if you are allergic to fluconazole, other antifungal medications
such as itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend) or any
other ,medications.
 do not take cisapride (Propulsid) while taking fluconazole.
 tell your doctor and pharmacist what prescription and nonprescription medications, vitamins,
nutritional supplements, and herbal products you are taking, especially amiodarone
(Cordarone); anticoagulants ('blood thinners') such as warfarin (Coumadin); astemizole
(Hismanal) (not available in the United States); benzodiazepines such as midazolam
(Versed);cyclosporine (Neoral, Sandimmune); disopyramide (Norpace); diuretics ('water pills')
such as hydrochlorothiazide (HydroDIURIL, Microzide); dofetilide (Tikosyn); erythromycin
(E.E.S, E-Mycin, Erythrocin); isoniazid (INH, Nydrazid); moxifloxacin (Avelox); oral
contraceptives (birth control pills); oral medicine for diabetes such as glipizide (Glucotrol),
glyburide (Diabeta, Micronase, Glycron, others), and tolbutamide (Orinase); phenytoin
(Dilantin); pimozide (Orap); procainamide (Procanbid, Pronestyl); quinidine (Quinidex);
rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); sotalolol (Betapace); sparfloxacin
(Zagam); tacrolimus (Prograf); terfenadine (Seldane) (not available in the United States);
theophylline (TheoDur); thioridazine (Mellaril); valproic acid (Depakene, Depakote); and
zidovudine (Retrovir).
 tell your doctor if you drink or have ever drunk large amounts of alcohol and if you have or
have ever had cancer; acquired immunodeficiency syndrome (AIDS); an irregular heartbeat;
or heart, kidney or liver disease .

252
 tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you
become pregnant while taking fluconazole, call your doctor.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip
the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for
a missed one.

What side effects can this medication cause?

Fluconazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go
away:

 headache
 dizziness
 diarrhea
 stomach pain
 heartburn
 change in ability to taste food

Some side effects can be serious. If you experience any of the following symptoms, call your doctor
immediately:

 upset stomach
 extreme tiredness
 unusual bruising or bleeding
 lack of energy
 loss of appetite
 pain in the upper right part of the stomach
 yellowing of the skin or eyes
 flu-like symptoms
 dark urine
 pale stools
 seizures
 rash
 hives
 itching
 swelling of the face , throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
 difficulty breathing or swallowing

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug
Administration's (FDA) MedWatch Adverse Event Reporting program online [at
http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at
room temperature and away from excess heat and moisture (not in the bathroom). Throw away any
medication that is outdated or no longer needed. Throw away any unused liquid medication after 14
days. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

253
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has
collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

 hallucinations (seeing things or hearing voices that do not exist)


 extreme fear that others are trying to harm you

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to
check your response to fluconazole.

Do not let anyone else take your medication. .Ask your pharmacist if you have questions about refilling
your prescription. If you still have symptoms of infection after you finish taking the fluconazole, call
your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-
counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary
supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a
hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

 Diflucan®

Last Revised - 04/01/2005


Last Reviewed - 08/01/2007

Drug Information: Fluocinolone Topical

254
(floo oh sin' oh lone)

Why is this medication prescribed?

Fluocinolone is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and
discomfort of various skin conditions.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more
information.

How should this medicine be used?

Fluocinolone comes in ointment, cream, solution, shampoo, and oil in various strengths for use on the
skin. It usually is applied two to four times a day. Follow the directions on your prescription label
carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use
fluocinolone exactly as directed. Do not use more or less of it or use it more often than prescribed by
your doctor. Do not apply it to other areas of your body or wrap or bandage the treated area unless
directed to do so by your doctor.

Wash or soak the affected area thoroughly before applying the medicine, unless it irritates your skin.
Then apply the ointment, cream, solution, or oil sparingly in a thin film and rub it in gently.

Use the shampoo as you would any normal shampoo. Wet your hair and scalp. Apply the shampoo
and gently massage the scalp. Rinse with water.

To use a solution on your scalp, part your hair, apply a small amount of the medicine on the affected
area, and rub it in gently. Protect the area from washing and rubbing until the solution dries. You may
wash your hair as usual but not right after applying the medicine.

Avoid prolonged use on the face, in the genital and rectal areas, and in skin creases and armpits
unless directed by your doctor.

If you are using fluocinolone on your face, keep it out of your eyes.

If you are using fluocinolone on a child's diaper area, do not use tight-fitting diapers or plastic pants.
Such use may increase side effects.

Do not apply cosmetics or other skin preparations on the treated area without talking with your doctor.

If your doctor tells you to wrap or bandage the treated area, follow these instructions:

 Soak the area in water or wash it well.


 While the skin is moist, gently rub the medication into the affected areas.
 Cover the area with plastic wrap (such as Saran Wrap or Handi-Wrap). The plastic may be
held in place with a gauze or elastic bandage or adhesive tape on normal skin beside the
treated area. (Instead of using plastic wrap, plastic gloves may be used for the hands, plastic
bags for the feet, or a shower cap for the scalp.)
 Carefully seal the edges of the plastic to make sure the wrap adheres closely to the skin. If the
affected area is moist, you can leave the edges of the plastic wrap partly unsealed or puncture
the wrap to allow excess moisture to escape.
 Leave the plastic wrapping in place as long as directed by your doctor. Usually wraps are left
in place no more than 12 hours each day.
 Cleanse the skin and reapply the medication each time a new plastic wrapping is applied. Call
your doctor if the treated area gets worse or if burning, swelling, redness, or oozing of pus
develops.

Do not discontinue treatment abruptly without talking to your doctor.

What special precautions should I follow?

255
Before using fluocinolone,

 tell your doctor and pharmacist if you are allergic to fluocinolone or any other drugs.
 tell your doctor and pharmacist what prescription and nonprescription medications you are
taking, especially cancer chemotherapy agents, other topical medications, and vitamins.
 tell your doctor if you have an infection or have ever had diabetes, glaucoma, cataracts, a
circulation disorder, or an immune disorder.
 tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you
become pregnant while using fluocinolone, call your doctor immediately.

What should I do if I forget a dose?

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose,
skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make
up for a missed one.

What side effects can this medication cause?

Fluocinolone may cause side effects. Tell your doctor if any of these symptoms are severe or do not
go away:

 drying or cracking of the skin


 acne
 itching
 burning
 change in skin color

If you experience any of the following symptoms, call your doctor immediately:

 severe skin rash


 difficulty breathing or swallowing
 wheezing
 skin infection (redness, swelling, or oozing pus)

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug
Administration's (FDA) MedWatch Adverse Event Reporting program online [at
http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at
room temperature and away from excess heat. Do not allow it to freeze. Throw away any medication
that is outdated or no longer needed. Do not use it to treat other skin conditions. Talk to your
pharmacist about the proper disposal of your medication.

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about
refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-
counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary
supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a
hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

256
 Capex® Shampoo  Lidex® Gel  Synemol® Emollient
 Derma-Smoothe/FS®  Lidex®-E Emollient Cream
Cream
 Lidex®
 Synalar®

Last Revised - 04/01/2000


Last Reviewed - 08/01/2007

Drug Information: Fluoxetine


257
(floo ox' e teen)

IMPORTANT WARNING:

A small number of children, teenagers, and young adults (up to 24 years of age) who took
antidepressants ('mood elevators') such as fluoxetine during clinical studies became suicidal (thinking
about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults
who take antidepressants to treat depression or other mental illnesses may be more likely to become
suicidal than children, teenagers, and young adults who do not take antidepressants to treat these
conditions. However, experts are not sure about how great this risk is and how much it should be
considered in deciding whether a child or teenager should take an antidepressant.You should know that
your mental health may change in unexpected ways when you take fluoxetine or other antidepressants
even if you are an adult over age 24. You may become suicidal, especially at the beginning of your
treatment and any time that your dose is increased or decreased. You, your family, or your caregiver
should call your doctor right away if you experience any of the following symptoms: new or worsening
depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry;
agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting
without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or
caregiver knows which symptoms may be serious so they can call the doctor when you are unable to
seek treatment on your own.Your healthcare provider will want to see you often while you are taking
fluoxetine, especially at the beginning of your treatment. Be sure to keep all appointments for office
visits with your doctor.The doctor or pharmacist will give you the manufacturer's patient information
sheet (Medication Guide) when you begin treatment with fluoxetine. Read the information carefully and
ask your doctor or pharmacist if you have any questions. You also can obtain the Medication Guide
from the FDA website: http://www.fda.gov/cder/drug/antidepressants/antidepressants_MG_2007.pdf.No
matter your age, before you take an antidepressant, you, your parent, or your caregiver should talk to
your doctor about the risks and benefits of treating your condition with an antidepressant or with other
treatments. You should also talk about the risks and benefits of not treating your condition. You should
know that having depression or another mental illness greatly increases the risk that you will become
suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood
that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or
has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and
personal and family medical history. You and your doctor will decide what type of treatment is right for
you.

Why is this medication prescribed?

Fluoxetine (Prozac) is used to treat depression, obsessive-compulsive disorder (bothersome thoughts


that won't go away and the need to perform certain actions over and over), some eating disorders, and
panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks). Fluoxetine
(Sarafem) is used to relieve the symptoms of premenstrual dysphoric disorder, including mood swings,
irritability, bloating, and breast tenderness. Fluoxetine is in a class of medications called selective
serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural
substance in the brain that helps maintain mental balance.

How should this medicine be used?

Fluoxetine (Prozac) comes as a capsule, a tablet, a delayed-release (long-acting) capsule, and a


solution (liquid) to take by mouth. Fluoxetine may be taken with or without food. Fluoxetine (Sarafem)
comes as a capsule to take by mouth. Fluoxetine (Prozac) capsules, tablets, and liquid are usually
taken once a day in the morning or twice a day, in the morning and at noon. Fluoxetine delayed-
released capsules are usually taken once a week. Fluoxetine (Sarafem) is usually taken once a day,
either every day of the month or on certain days of the month. Take fluoxetine at around the same
time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or
pharmacist to explain any part you do not understand. Take fluoxetine exactly as directed. Do not take
more or less of it or take it more often than prescribed by your doctor.

Your doctor may start you on a low dose of fluoxetine and gradually increase your dose.

It may take 4 to 5 weeks or longer before you feel the full benefit of fluoxetine. Continue to take
fluoxetine even if you feel well. Do not stop taking fluoxetine without talking to your doctor. If you
suddenly stop taking fluoxetine, you may experience withdrawal symptoms such as mood changes,
irritability, agitation, dizziness, numbness or tingling in the hands or feet, anxiety, confusion, headache,
tiredness, and difficulty falling asleep or staying asleep. Your doctor will probably decrease your dose
gradually.

258
Other uses for this medicine

Fluoxetine is also sometimes used to treat alcoholism, attention-deficit disorder, borderline personality
disorder, sleep disorders, headaches, mental illness, posttraumatic stress disorder, Tourette's
syndrome, obesity, sexual problems, and phobias. Talk to your doctor about the possible risks of using
this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking fluoxetine,

 tell your doctor and pharmacist if you are allergic to fluoxetine or any other medications.
 tell your doctor if you are taking pimozide (Orap),thioridazine or monoamine oxidase (MAO)
inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam,
Zelapar), and tranylcypromine (Parnate), or if you have stopped taking a monoamine oxidase
inhibitor within the past 2 weeks. Your doctor will probably tell you that you should not take
fluoxetine. If you stop taking fluoxetine, you should wait at least 5 weeks before you begin to
take thioridazine or a monoamine oxidase inhibitor.
 tell your doctor and pharmacist what other prescription and nonprescription medications and
vitamins you are taking or plan to take. Be sure to mention any of the following: alprazolam
(Xanax); anticoagulants ('blood thinners') such as warfarin (Coumadin); antidepressants
(mood elevators) such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine
(Anafranil), desipramine (Norpramin), doxepin, imipramine (Tofranil), nortriptyline (Aventyl,
Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); aspirin and other nonsteroidal
anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin), and naproxen
(Aleve, Naprosyn); diazepam (Valium); digoxin (Lanoxin); diuretics (water pills), flecainide
(Tambocor); insulin or oral medications for diabetes; lithium (Eskalith, Lithobid); medications
for anxiety and Parkinson's disease; medications for mental illness such as clozapine
(Clozaril), haloperidol (Haldol), and pimozide (Orap); medications for migraine headaches
such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge),
rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); medications for seizures
such as carbamazepine (Tegretol) and phenytoin (Dilantin); sedatives; sibutramine (Meridia);
sleeping pills; tramadol (Ultram); tranquilizers; and vinblastine (Velban). Your doctor may need
to change the doses of your medications or monitor you carefully for side effects.
 tell your doctor what nutritional supplements you are taking, especially products that contain
St. John's wort or tryptophan.
 tell your doctor if you are being treated with electroshock therapy (procedure in which small
electric shocks are administered to the brain to treat certain mental illnesses), if you have
recently had a heart attack and if you have or have ever had diabetes, seizures, or liver or
heart disease.
 tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you
become pregnant while taking fluoxetine, call your doctor.
 you should know that fluoxetine may make you drowsy. Do not drive a car or operate
machinery until you know how this medication affects you.
 remember that alcohol can add to the drowsiness caused by this medication.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip
the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for
a missed one.

What side effects can this medication cause?

Fluoxetine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go
away:

 nervousness
 nausea
 dry mouth
 sore throat
 drowsiness
 weakness
 uncontrollable shaking of a part of the body
 loss of appetite

259
 weight loss
 changes in sex drive or ability
 excessive sweating

Some side effects can be serious. If you experience any of the following symptoms or those listed in
the IMPORTANT WARNING section, call your doctor immediately:

 rash
 hives
 fever
 joint pain
 swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
 difficulty breathing or swallowing
 seeing things or hearing voices that do not exist (hallucinating)
 seizures

Fluoxetine may cause other side effects. Call your doctor if you have any unusual problems while
taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug
Administration's (FDA) MedWatch Adverse Event Reporting program online [at
http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at
room temperature and away from excess heat and moisture (not in the bathroom). Throw away any
medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of
your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has
collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

 unsteadiness
 confusion
 unresponsiveness
 nervousness
 uncontrollable shaking of a part of the body
 dizziness
 rapid, irregular, or pounding heartbeat
 seeing things or hearing voices that do not exist (hallucinating)
 fever
 fainting
 coma (loss of consciousness for a period of time)

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about
refilling your prescription

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-
counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary
supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a
hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

260
 Prozac®  Sarafem®

 Prozac® Weekly  Symbyax® (as a combination product


containing fluoxetine and olanzapine)

Last Revised - 02/01/2008


Last Reviewed - 04/01/2000

Drug Information: Folic Acid


261
(foe' lik)

Why is this medication prescribed?

Folic acid is used to treat or prevent folic acid deficiency. It is a B-complex vitamin needed by the body
to manufacture red blood cells. A deficiency of this vitamin causes certain types of anemia (low red
blood cell count).

How should this medicine be used?

Folic acid comes in tablets. It usually is taken once a day. Follow the directions on your prescription
label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take folic
acid exactly as directed. Do not take more or less of it or take it more often than prescribed by your
doctor.

If you are taking folic acid to treat a deficiency, you probably will feel better quickly, often within 24
hours. However, do not stop taking this drug until your doctor tells you to do so.

Other uses for this medicine

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more
information.

What special precautions should I follow?

Before taking folic acid,

 tell your doctor and pharmacist if you are allergic to folic acid or any other drugs.
 tell your doctor and pharmacist what prescription and nonprescription medications you are
taking, especially phenytoin (Dilantin) and vitamins.

What special dietary instructions should I follow?

Your doctor may tell you to eat more liver, foods prepared from dried yeast, fruit, and fresh leafy green
vegetables to increase the folic acid in your diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip
the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for
a missed one.

What side effects can this medication cause?

Folic acid may cause side effects. If you experience any of the following symptoms, call your doctor
immediately:

 skin rash
 itching
 redness
 difficulty breathing

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug
Administration's (FDA) MedWatch Adverse Event Reporting program online [at
http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at
room temperature and away from excess heat and moisture (not in the bathroom). Throw away any
medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of
your medication.

In case of emergency/overdose

262
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has
collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to
check your response to folic acid.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about
refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-
counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary
supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a
hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

 Folvite®

Last Revised - 04/01/2003


Last Reviewed - 08/01/2007

Drug Information: Furosemide

263
(fyoor oh' se mide)

Why is this medication prescribed?

Furosemide, a 'water pill,' is used to reduce the swelling and fluid retention caused by various medical
problems, including heart or liver disease. It is also used to treat high blood pressure. It causes the
kidneys to get rid of unneeded water and salt from the body into the urine.

This medicine is sometimes prescribed for other uses; ask your doctor or pharmacist for more
information.

How should this medicine be used?

Furosemide comes as a tablet and liquid to take by mouth. It usually is taken once a day in the
morning or twice a day in the morning and afternoon. Follow the directions on your prescription label
carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take
furosemide exactly as directed. Do not take more or less of it or take it more often than prescribed by
your doctor.

Furosemide controls high blood pressure but does not cure it. Continue to take furosemide even if you
feel well. Do not stop taking furosemide without talking to your doctor.

What special precautions should I follow?

Before taking furosemide,

 tell your doctor and pharmacist if you are allergic to furosemide, sulfa drugs, or any other
drugs.
 tell your doctor and pharmacist what prescription and nonprescription medications you are
taking, especially other medications for high blood pressure, aspirin, corticosteroids (e.g.,
prednisone), digoxin (Lanoxin), indomethacin (Indocin), lithium (Eskalith, Lithobid),
medications for diabetes, probenecid (Benemid), and vitamins. If you also are taking
cholestyramine or colestipol, take it at least 1 hour after taking furosemide.
 tell your doctor if you have or have ever had diabetes, gout, or kidney or liver disease.
 tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Do not
breast-feed while taking this medicine. If you become pregnant while taking furosemide, call
your doctor.
 if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking
furosemide.
 plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing,
sunglasses, and sunscreen. Furosemide may make your skin sensitive to sunlight.

What special dietary instructions should I follow?

Follow your doctor's directions. They may include a daily exercise program and a low-sodium or low-
salt diet, potassium supplements, and increased amounts of potassium-rich foods (e.g., bananas,
prunes, raisins, and orange juice) in your diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for your next dose,
skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make
up for a missed one.

What side effects can this medication cause?

264
Frequent urination may last for up to 6 hours after a dose and should decrease after you take
furosemide for a few weeks. Tell your doctor if any of these symptoms are severe or do not go away:

 muscle cramps
 weakness
 dizziness
 confusion
 thirst
 upset stomach
 vomiting
 blurred vision
 headache
 restlessness
 constipation

If you have any of the following symptoms, call your doctor immediately:

 fever
 sore throat
 ringing in the ears
 unusual bleeding or bruising
 loss of hearing
 severe rash with peeling skin
 difficulty breathing or swallowing
 rapid, excessive weight loss

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug
Administration's (FDA) MedWatch Adverse Event Reporting program online [at
http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at
room temperature and away from excess heat and moisture (not in the bathroom). Throw away
unused furosemide liquid after 60 days. Throw away any medicine that is outdated or no longer
needed. Talk to your pharmacist about the proper disposal of your medicine.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has
collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked
regularly, and blood tests should be done occasionally.

Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling
your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-
counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary
supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a
hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

 Lasix®

Last Revised - 04/01/2003


Last Reviewed - 08/01/2007

265

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