Pathogen Children Adults

Watery Diarrhea Erythromycin 30 mg/kg/day divided every 8 hours orally × 3 Doxycycline 300 mg orally × 1 day
Vibrio cholerae days; azithromycin 10 mg/kg/day given orally once daily × 3 Alternatives: tetracycline 500 mg orally four times daily × 3
O1 days days; erythromycin 250 mg orally every 8 hours × 3 days;
azithromycin 500 mg orally once daily × 3 days
Enterotoxigenic Azithromycin 10 mg/kg/day given orally once daily × 3 days; Ciprofloxacin 750 mg orally once daily × 1–3 days. Alternatives:
Escherichia coli ceftriaxone 50 mg/kg/day given IV once daily × 3 days rifaximin 200 mg orally three times daily × 3 days; azithromycin
1,000 mg orally × 1 day or 500 mg orally daily × 3 days
Dysenteric Diarrhea Azithromycin 10 mg/kg/day given orally once daily × 3 days; Ciprofloxacin 750 mg orally once daily × 3 days; levofloxacin
Shigella species ceftriaxone 50 mg/kg/day given IV once daily × 3 days 500 mg orally once daily × 3 days
Alternatives: azithromycin 500 mg orally once daily × 3 days
Salmonella Nontyphoidal Ceftriaxone 100 mg/kg/day divided IV every 12 hours × 7–10 Ciprofloxacin 750 mg orally once daily × 7–10 days;
days; azithromycin 20 mg/kg/day orally once daily × 7 days levofloxacin 500 mg orally once daily × 7–10 days
Alternatives: azithromycin 500 mg orally once daily × 7 days
For immunocompromised patients, duration should be
increased to 14 days for both fluoroquinolones and
azithromycin