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Drugs Used in Asthma
Drugs Used in Asthma
Bronchodilators are:
1 F beta 2 antagonists
1 F beta 1 agonists
1 T beta 2 agonists
1 T antimuscarinic drugs
1 T methylxanthines
Bronchodilators are: beta 2 agonists, muscarinic receptor antagonists and methylxanthines
Using metered dose inhaler -aerosol the dose of........ /puff is administered:
3 F 1ug
3 F 10 ug
3 T 100ug
1 F 1mg
1 F 10 mg
Using metered dose inhaler-aerosol the dose of 100 ug/puff is administered
Ipratropium:
1 F is administered orally .
2 F is more effective than salbutamol
3 T could precipitate acute glaucoma
1 T is used for patients with heart disease
1 F but cannot be used for patients with thyreotoxicosis
Ipratropium is short acting drug administred by inhalation (absorption from GIT is low). The degree and rate of onset of
bronchodilatation is less than that of salbutamol. The drug can precipitate glaucoma if nebulized doses are given via a
facemask. Ipratropium is used for patients with heart disease or thyreotoxicosis in whom beta agonists are unsuitable.
Aminophylline is:
1 T used i.v.( injections)
1 T used orally
1 T used orally in the form of sustained release preparations
1 F by inhalation
1 T used i.v. (infusions)
Aminophylline is used i.v. (by slow injection and/or infusion.) in patients with severe asthma and is used orally in less
severe cases or to reduce symptoms, especially at night. Oral theophylline preparations are widely used in the form of sustained
release preparations
Glucocorticoids are:
1 F bronchodilators with a large effect on early-phase response
1 T not bronchodilators, are not effective in the treatment of the early response to the eliciting agent
1 T administered by inhalation they are extremely powerful anti-inflammatory drugs.
1 T considered as first-line drugs in asthma prophylaxis, for all but the mildest cases
1 T for severe asthma an oral glucocorticoid is indicated
Glucocorticoids are not bronchodilators, they are not effective in the treatment of the early-phase response.Glucocortiocoids
given by inhalation are able to control the disease without causing adverse systemic effects or adrenal suppression. They are
considered first-line drugs in asthma prophylaxis. For severe asthma an oral glucocorticoid is indicated.