Mindanao State University – Iligan Institute of Technology Student: SALIMBAGAT, CHRISTINE.

P Section: 262

PHARMACOLOGY

DRUG STUDY

Brand Name: Augmentin Generic Name: Amoxicillin Clavulante Drug Classification: Aminopenicillins/Beta Lactamase Inhibitors
Dosage, Route & Frequency Drug-Drug &
Side Effects Adverse Reactions
Prescribe Drug Action Drug-Food Indications Contraindications
Recommended (By System) (By System)
d Interactions
Mild to Moderate Infections Used alone, clavulanic Drug: TETRACY Infections caused by Combination shares GI: Nausea, vomiting, GI: Diarrhea, nausea,
Adult: PO 250 or 500 mg acid antibacterial CLINES may susceptible beta- toxic potential of diarrhea, gas, stomach vomiting.
tablet (each with 125 mg activity is weak. In inhibit activity lactamase-producing ampicillin. pain Skin: Rash, urticaria.
clavulanic acid) q8–12h; combination, it inhibits of organisms: lower Hypersensitivity to Skin: Skin rash or itching, Other: Candidal
Sustained-release tabs: 2 enzyme (beta- amoxicillin; pro respiratory tract penicillins; infectious white patches in your vaginitis; moderate
tablets (2000 mg lactamase) degradation benecid prolon infections, acute mononucleosis. mouth or throat increases in serum ALT,
amoxicillin/125 mg of amoxicillin and by gs the activity bacterial sinusitis, Cautious Use CNS: Headache AST;glomerulonephritis
clavulanate) q12h x 7–10 d synergism extends of amoxicillin. community acquired Pregnancy (category B), Urogenital: Vaginal yeast ; agranulocytosis (rare).
Child: PO <40 kg, 20–40 both spectrum of pneumonia, otitis lactation. infection (itching
mg/kg/d (based on activity and bactericidal media, sinusitis, skin or discharge)
amoxicillin component) effect of amoxicillin and skin structure
divided q8–12h; >3 mo, 90 against many strains of infections, and UTI.
mg/kg/d of 600 ES divided beta-lactamase-
q12h x 10 d producing bacteria
Neonate/Infant: PO <3 resistant to amoxicillin
mo, 30 mg/kg/d (amoxicillin) alone.
divided q12h
Responsibilities in the Nursing Process (ADPIE) Responsibilities in the Nursing Process (ADPIE)
A - ● Obtain a history before initiating therapy to determine previous use of and I - PO: Administer around the clock. Administer at the start of a meal to enhance absorption and to
reactions to penicillins or cephalosporins. Observe for signs and symptoms of decrease GI side effects. Do not administer with high fat meals. Pedi: Do not administer 250-mg
anaphylaxis. Monitor bowel function chewable tablets to children 40 kg due to clavulanate content. ● Pedi: Teach parents or caregivers to
D - Risk for infection (Indications, Side Effects), Noncompliance (Patient/Family calculate and measure doses accurately
Teaching) E - Resolution of the signs and symptoms of infection. Length of time for complete resolution depends on
P - Plan medication administration to avoid disruption. the organism and site of infection
Prepare medications for ONE patient at a time. Check expiration date.
Follow the SEVEN RIGHTS of medication preparation.
Complete necessary focused assessments, lab values, and/or vital signs, and document
on MAR.Provide patient education as necessary.