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Chapter 19 Microbial Diseases of The Skin and Wounds
Chapter 19 Microbial Diseases of The Skin and Wounds
Functions of the skin • Cuts, scrapes, surgery, burns, bites, etc. Normal Microbiota of the Skin
• Allow microbes to infect the deeper tissues of the
• Prevents excessive water loss body Skin microbiota
• Regulates temperature • In most cases, other body defenses eliminate
• Involved in sensory phenomena infection • Made up of various microbes
• Assists in vitamin D formation • Can result in severe or fatal diseases o Yeast
• Barrier against microbial invaders Malassezia
Skin microbiota o Bacteria
Composed of two main layers Staphylococcus, Micrococcus,
• Normally harmless microbes present on the skin and the diphtheroids
• Dermis • Compete with potential pathogens for nutrients
• Epidermis and space May produce disease
• Cannot be completely removed through
Wounds cleansing • If penetrate epidermis or if immune system is
• Typically grow in moist areas of the skin suppressed
• Trauma to any tissue of the body
• Waste products cause body odor
Diagnosis
by observation of hyphae in skin
sample, biopsy material, or
• Acquired when spores enter wounds
over 30 genera of cerebrospinal fluid Disease is permanently
Phaeohyphomycosis • Disease is variable in presentation
fungi Treatment destructive to tissues
• Depends on site of fungal colonization
treated with itraconazole
Prevention