DRUG Indication Mode of Action
Diagnosis
Miconazole Is used to treat skin
Nitrate infections such as athlete’s
foot, jock itch, ringworm
Trade: Zeasorb- and other fungal skin
AF infections (candidiasis).
Class: Antifungal This medication is also
Therapeutic: used to treat a skin
Fungicidal condition known as
Route: Topical pityriasis (tinea
versicolor), a fungal
infection that causes
lightening or darkening of
the skin of the neck, chest,
arms, or legs.
Albendazole Treatment of parenchymal
neurocysticercosis due to
Trade: Albenza active lesions caused by
Class: larval forms of pork
Anthelmintic tapeworm. Taenia solium ;
Route: Oral Treatment of cystic
Dosage: 200mg hydatid disease of the
liver, lung, and
peritoneum caused by
larval forms of dog
tapeworm, Echinococcus
granulosus
Contraindication Side Effects Adverse Effects Nursing Plan of Action
Alters fungal cell - Contraindicated with - Irritation - Irritation Impaired - Assess skin, noting
membrane allergy to miconazole - Burning - Burning Skin type(s) of disruption and
permeability, causing or components used in - Stinging - Maceration Integrity general health of skin.
cell death; may also preparation. - Allergic contact - Determine client’s age
alter fungal cell DNA - Use cautiously with dermatitis and developmental
and RNA metabolism pregnancy and - Rash factors or ability to care
or cause lactation for self.
accumulation of toxic - Maintain and instruct in
peroxides good skin integrity.
intracellularly - Perform routine skin
inspections, describing
observed changes. Note
skin color and texture.
- Emphasize importance of
proper skin care to
alleviate discomfort and
minimize skin
Inhibitory effect on Hypersensitivity to - Headache CNS- headache (11%), Fluid volume - Note the presence of
tubulin benzimidazole - Dizziness raised intracranial deficit other factors that may
polymerization, compounds or any - Nausea pressure (2%), contribute to a lack of
resulting in loss of component of the - Vomiting dizziness/vertigo, fluid intake or loss of
cytoplasmic product - Fever meningeal signs (1%) fluid by various routes.
microtubules - Observe/ Measure
Dermatologic- urinary output (hourly/
Reversible alopecia 24-hr totals). Note the
Pharmacokinetics (2%), erythema color and specific gravity.
multiforme, Stevens- - Administer fluids and
Absorption: Johnson syndrome (post electrolytes.
Distribution: marketing) - Keep fluids within the
Metabolism: client’s reach and
Elimination: GI- Abdominal pain, encourage frequent
Drug Half-life: 8h-12h Nausea/Vomiting (6%) intake, as appropriate.
- Discuss signs/symptoms
indicating need for
Hepatic- Abnormal LFTs emergent or further
(16%); acute liver evaluation and follow-
failure, hepatitis (post up.
marketing)

Hematologic-
Lymphatic-
Agranulocytosis,
granulocytopenia,
leukopenia,
pancytopenia,
thrombocytopenia (less
than 1%); aplastic
anemia, bone marrow
suppression,
neutropenia (post
marketing).

Miscellaneous – Fever
(1%); acute renal failure
(post marketing)

Drug Interactions:
- Cimetidine
- Dexamethasone
- Grapefruit Juice
- Praziquantel
- Theophylline