Dr.

Arcadio Santos National High School

Km. 15 East Service Rd.,SMDP, Pque. City

A Research Paper Title

'''EFFECTIVENESS OF LUXXE WHITE GLUTHTHIONE IN IMPROVING

SKIN COLOR OF FILIPINOS''

in partial fulfilment of the requirements

in English 10

Summited By:

Yramiel H. Ernesto

10 - Jade

Submitted to:

Ms. Michelle O. Guevarra

Date Submitted:
 February 15, 2019

ACKNOWLEDGEMENT

First of all I'm happy because this English Research is complete due to
support many people. This researchhas been deeply appreciated by Ms.
Michelle Guevarra who has cooperate for this research. I'm verry grateful
for non stop teaching for this kind of activities. She gave us a guide so we
could do it and finish this properly. I also express my acknowledgement to
myself and other person who want to know ore about luxxe white
glutathione. And lastly I would like to thank my parent and my friend for
helping to me and encouraging me to finish this kind of research because
this is the way to know more about this kind of topic.
 TABLE OF CONTENTS

ACKNOWLEDGEMENT....................................................................... i

I. OVERVIEW OF THE STUDY

A. INTRODUCTION

Definitio of Terminologies .............................................. 1

Signiicant of The Study .................................................. 2

Statement of The Problem ............................................. 3

B. RELATED LITERATURE

................................................ 4

................................................ 5

................................................ 6

................................................ 7
 ................................................ 8

C. CONCLUTION AND FINDINGS ...................................... 9

II. BIBLIOGRAPHY ................................................. ii

III. APPENDICES ................................................. iii

RESEARCHER TITLE

General Topic: Health and Medecine

Broad Topic: Skin Whitening

Specific Topic: Effectiness of Glutathione

Research Title: Effectiveness of Luxxe White Glutathione in improving skin

color of Filipino.
TERMINOLOGIES
The following terminologies are defined technically and operational:

1. Glutathione that contains are amino acid residue each of glutamic acid,
cystine, and glycine, that occurs widely in plant and animal tissue, and that plays an
important rolo in biological oxidation-detection processess and as acoenzyme.

2. Antioxidant a substance such as vitamin C or E that removes potentially

damaging agent in a living organism.

3. Colagen the main structural protien found in skin and other connective tissue,
widely ussd in purified from for cosmetic sufgical treatment.

4. Detoxification is a medical treatment of an alcoholic or drug addict involving

abstention from drink of drugs until the blood-stream is free of toxin.

5. Toxin an antigenic poison or venom of plants or animal origin, specailly one

produce by or derived from microorganism and causing diseases when present at low in
the body.

SIGNIFICANT OF STUDY

This study will aimed to for the thruth about Effectiveness Luxxe White
Glutathione in improving skin color of Filipinos and its aim to give enough
knowledge for the researchers because the research gave and have the survey
to the person who wants to know more about skin whitening.
 For the adults, it can affect to thier skin that may cause allergies and some may
cause infection.

For the teenagers, this research gave enough knowledge about the using skin
whitening, its helps to many researcher of this problem about skin whitening to
want to have their own beautful skin.

For the Parents, many parents are also use this kind of body whitening,

because they want to express ther skin.

STATEMENT OF THE PROBLEM

This study seeks to answer the following question:

1. What are the symtoms of glutathione deficiency?

2. What are the benefits of Luxxe White Glutathione?

3. What are the effect of Glutathione?

RELATED LITERATURE

1. What are the symptoms of glutathione deficiency?

a. Signs of metabolic acidosis may include nausea, vomiting and tatigue.The

severe form of glutathione synthetase deficiency usually cuases the same signs and
symptoms. Seen in the milter forms of the deficiency, but can also affect the brain,
which causes neurological problem. Is a genetic metabolic disorder that affects the
body’s ability to produce an important substance called glutathione. People with
glutathione synthetase deficiency do not have enough of the molecule called glutathione
synthetase, which helps the body produce glutathione. People with glutathione
synthetase deficiency can have mild, moderate, or severe disease.The glutathione
component is an important molecule to the body as it compromises of three amino acids
essential for maintaining the proper functioning of the immune system. Every person’s
body produces glutathione. This is a natural antioxidant that is responsible for getting rid
of harmful chemical and substances that the human body comes into contact with.
When a person is no longer able to produce a certain amount of this antioxidant it then
becomes a deficiency. Once this happens a person’s body becomes susceptible to a lot
of foreign invaders.
b. A disorder that prevents the production of an important molecule called glutathione.
Glutathione helps prevent damage to cells by neutralizing harmful molecules generated
during energy production. Glutathione also plays a role in processing medications and
cancer-causing compounds, and building DNA, proteins, and other important cellular
components.In addition to the features present in moderate glutathione synthetase
deficiency, individuals affected by the severe form of this disorder may experience
neurological symptoms. It can be classified into three types: mild, moderate, and
severe. Mild glutathione synthetase deficiency usually results in the destruction of red
blood cells.Glutathione is a substance that not too many people are familiar with. This
particular substance is an antioxidant that is important to the human body. Most people
are able to produce this substance within their body but sometimes a person’s system
falls short of production.
c. Glutathione synthetase deficiency is characterised by hemolytic anemia, associated
with metabolic acidosis and 5-oxoprolinuria in moderate forms, and with progressive
neurological symptoms and recurrent bacterial infections in the most severe forms. The
participation of both tissue and circulating glutathione deficiency in disease
pathogenesis is likely to be subtle and not easily defined. Despite these difficulties, a
number of inherited conditions of glutathione deficiency are known, and acquired ones
are being identified. Examples of the acquired deficiency state include idiopathic
pulmonary fibrosis, human immunodeficiency virus-related disease, and respiratory
distress syndrome has multiple metabolic actions that are essential for cellular
homeostasis. In spite of this important role in cellular physiology, disease states due to
glutathione deficiency are not common.

2. What are the benefits of Luxxe White Glutathione?

a. Health benefits of a dietary on oxidative reductional is typically carried out in
conjuction. Dietary treatment rich in antioxidant have thier potential in reducing
oxidative stress. To assess oxidative stress reduction benefits and dieatary products. It
also extremely important cell protection. Glutathione is a primary protection of skin, lens,
cornea, and retina against radiation damage. It is also aids in detoxifying the liver,
kidney, lungs and other organs, aside from its antioxidant properties and liver
detoxification capabilities.
b. Glutathion is a substance produce naturally by the liver. It also found in fruits,
vegetables and meat. Glutathione levels in the body may be reduce by a number of
factors, including poor nutrition, environmental toxins, and stress its levels also decline
with age in addition to being produce naturally by body, glutathione can be given
intravenuosly topically, or as an inhalant also available as an oral supplement in capsule
and liquid form. However, oral ingestion of glutathione may not be as effective as
intravenous delivery for some conditions.

c. Luxxe White consistently heiled at the most effective whitening supplement for
several years and just recently as the most powerful whitening supplement. It is
clinically tasted to be easily absored by the body, compare to regular glutathione.

3. What the effect of glutathione? in the following.

a. Skin lack of any publishied reliable source of evidence supporting the efficacy of
intravenous glutathione in lightening skin, undefined dose and duration of intravenous
injections, excepting the recommendation of manufactures, which have no apparent
scientific basis. Need for indefinite perhaps lifelong maintenance with either oral or
intravenous GSH, even after the skin lightening has been attined.
b. Liver glutathione , the master of antioxidant , is found in every cell and abudant in
the liver. It has anti-flammatory properties and plays important role in detoxificaion.

c. Reproductive System its support to the immune system, helps to prevent and treat
cancer. Removes free radicals and heavy metals from the body, recycle antioxidants for
re-use master detoxifier and most powerful antioxidant and control the in flammation. Is
the key for preventing aging, cancer heart desease. It also essential for treating
everything from autism to cancer and desease and much more.

CONCLUSION AND FINDINGS

The following are the result of the study conducted:

1. Therefore the intention of this topic was to underscore the priority

of enzymes.

2. Although any kind of kinetically competitive reaction may interfere

with a slow equilibration between redox couples, enzymatic ones are
the most likely candidates.

3. However, the bimolecular rate constants for the spontaneous

reactions of low molecular mass thiols with hydroperoxides.
4. Some patients develop secondary or even tertiary, I will focus on
the recent advancesmentds in the understanding of cancer regarding
iron and thiol compounds that appears independent but are
interindepend in many aspects.

5. In contrast, cancer is a digital diseease, which means that it

consists of stepwise processes and is all or nothing for the

generetion of milignant tumor.