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  • EBM Summary

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    Fu Xiao Shan
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    1. The document outlines steps for conducting an effective literature search: phrase the research question, rank search terms by importance, expand the search, intersect results, and examine yields for irrelevant results. 2. Key concepts in evaluating risk are defined, including relative risk (RR), confidence intervals (CI), and how RR values above or below 1 indicate harmful or beneficial effects. 3. An example is given of a treatment with an RR of 0.285 [95% CI: 0.1 – 0.4], meaning it reduces risk of disease by 71% according to the point estimate, with a range of 60-90% risk reduction based on the CI.

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    1. The document outlines steps for conducting an effective literature search: phrase the research question, rank search terms by importance, expand the search, intersect results, and examine yields for irrelevant results. 2. Key concepts in evaluating risk are defined, including relative risk (RR), confidence intervals (CI), and how RR values above or below 1 indicate harmful or beneficial effects. 3. An example is given of a treatment with an RR of 0.285 [95% CI: 0.1 – 0.4], meaning it reduces risk of disease by 71% according to the point estimate, with a range of 60-90% risk reduction based on the CI.

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    © All Rights Reserved
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    17 views6 pages

    EBM Summary

    Uploaded by

    Fu Xiao Shan
    1. The document outlines steps for conducting an effective literature search: phrase the research question, rank search terms by importance, expand the search, intersect results, and examine yields for irrelevant results. 2. Key concepts in evaluating risk are defined, including relative risk (RR), confidence intervals (CI), and how RR values above or below 1 indicate harmful or beneficial effects. 3. An example is given of a treatment with an RR of 0.285 [95% CI: 0.1 – 0.4], meaning it reduces risk of disease by 71% according to the point estimate, with a range of 60-90% risk reduction based on the CI.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    of 6

    Summary

    1. Phrase your research question properly


    2. Rank the terms in order of importance
    3. Expand your search
    4. Intersect the results
    5. Examine yield for misses and mishits

    Painless Evidenced Based Medicine, 2008


    80 - 60 kg 60 kg 80 - 60 kg
    NOW
    80 kg 80 kg

    80 kg 60 kg 25% 75% 20 kg

    My past My present The % The % The


    weight I weight absolute
    weight weight that weight I
    lost
    remained lost

    Credits to the Owner – EBM Lecture


    80 kg 60 kg 25% 75% 20 kg

    My past My present The % The % The absolute


    weight weight weight I lost weight that weight I lost
    remained

    Control Experimental RRR RR ARR

    Rc Rt Rc-Rt/Rc Rt/Rc Rc-Rt

    The % risk The % risk The absolute


    The past The present
    risk that was that risk removed
    risk
    reduced remained

    Credits to the Owner – EBM Lecture


    Risk t
    Relative Risk =
    Risk c

    RR < 1 RR = 1 RR > 1

    Beneficial No Effect Harmful

    RR: 0.285RR:
    [95% CI: 0.1 – 0.4]
    0.285
    Credits to the Owner – EBM Lecture
    RR: 0.285 [95% CI: 0.1 – 0.4]

    Given the intervention, RR for RR for


    95% of the time, the BEST WORST
    results reflect the true case case
    value or is reliable scenario scenario
    • If the confidence interval crosses or
    includes 1, it is NOT STATISTICALLY
    SIGNIFICANT
    • RR>1: HARMFUL!
    5
    Credits to the Owner – EBM Lecture
    RR: 0.285 [95% CI: 0.1 – 0.4]
    • The REMAINING RISK of acquiring the disease given the
    treatment is 29%

    • The treatment REDUCED RISK of disease by 71%

    • Best case scenario: RR = 0.1


    • Remaining Risk is 10%
    • Tx reduced risk by 90%

    • Worst case scenario: RR = 0.4


    • Remaining Risk is 40%
    • Tx reduced risk by 60%

    • The LOWER the RR, the better, more beneficial!


    6
    Credits to the Owner – EBM Lecture

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