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  • Resistensi Dec - Conc Dec - Transport: No. Gen SNP MAF Manifestasi

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    ZAHROTUN NAFIAH -
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    The document lists 11 genes associated with drug metabolism and response. For each gene, it provides the SNP ID, minor allele frequency, and how the SNP affects the gene's manifestation such as decreasing enzyme concentration, activity, or response. A variety of SNPs are shown across the genes with minor allele frequencies ranging from 0.0008 to 0.495.

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    Minor Alel Frequencies of Carbamazepin Gene

    Original Title

    DATA MAF

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    The document lists 11 genes associated with drug metabolism and response. For each gene, it provides the SNP ID, minor allele frequency, and how the SNP affects the gene's manifestation such as decreasing enzyme concentration, activity, or response. A variety of SNPs are shown across the genes with minor allele frequencies ranging from 0.0008 to 0.495.

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    © All Rights Reserved
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    8 views1 page

    Resistensi Dec - Conc Dec - Transport: No. Gen SNP MAF Manifestasi

    Uploaded by

    ZAHROTUN NAFIAH -
    The document lists 11 genes associated with drug metabolism and response. For each gene, it provides the SNP ID, minor allele frequency, and how the SNP affects the gene's manifestation such as decreasing enzyme concentration, activity, or response. A variety of SNPs are shown across the genes with minor allele frequencies ranging from 0.0008 to 0.495.

    Copyright:

    © All Rights Reserved
    Download as XLSX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as xlsx, pdf, or txt
    of 1

    No.

    Gen SNP MAF MANIFESTASI


    1 ABCB1 rs1045642 C>T A : 0.3952 Resistensi
    rs2032582 A>C,T A : 0.3343 Dec.Conc
    2 ABCC2 rs717620 C>T 0.135
    rs227369 G>T 0.3654 Dec.Transport
    rs3740066 C>T 0.2881
    3 CYP2C19 rs4244285 G>A 0.2214
    Dec. Enzyme activity
    rs4986893 G>A 0.0142
    4 CYP3A5 rs776746 G>A T : 0.3786
    Dec. Enzyme activity
    rs28365083 C>A T : 0.0008
    5 CYP3A4 rs2740574 A>G C : 0.2308
    5 CYP2C8 rs11572080 C>A,T 0.0457 Penurunan & penghapusan aktivitas enzim
    6 CYP1A2 rs2069514 G>A 0.2089
    Mengurangi & mengahkiri peningkatan
    rs762551 C>A 0.3702 kemampuan menginduksi enzim
    7 PXR* rs2276707 C>T 0.3197 Conc & respon
    8 HNF4a* rs2071197 G>A 0.1977 Respon
    9 SCN3A rs11903851 C>T 0.22
    rs1439806 G>A 0.36
    rs1439807 A>G 0.26
    rs7596422 G>A 0.41
    rs16850186 G>A 0.31
    rs16822786 C>T 0.22
    rs16822786 G>A 0.32
    rs16822786 G>A 0.11
    10 SCN2A rs10182570 A>C 0.39
    rs1446579 A>G 0.43
    rs353139 C>T 0.47
    rs16850331 C>T 0.24
    rs17183814 G>A 0.07
    rs7581811 G>C 0.49
    Respon
    rs7592445 T>C 0.23
    rs1965757 A>G 0.27
    rs2304016 C>T 0.25
    rs2304016 A>G 0.03
    rs12993173 G>T 0.49
    rs935403 G>A 0.31
    rs1579865 C>T 0.26
    rs4667485 G>C 0.42
    rs12467383 G>A 0.22
    rs1469649 G>A 0.43
    11 SCN1A rs10182473 T>C 0.38
    rs1020853 G>T 0.38
    rs2298771 A>G 0.21
    rs10930195 A>T 0.49

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