SBK 1013

Introduction to
Biochemistry
INSTRUCTIONAL PLAN

Department of Biology
Faculty of Science and Mathematics
Sultan Idris Education University

SESSION 2016/2017

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Head of Department‘s Verification:

Date:

INSTRUCTIONAL PLAN
Faculty : Science and Mathematic
Department : Biology
Semester : 1Session : 2016/2017
Course name : Introduction to Biochemistry
Course code : SBK 1013
Credit Hour : 2+1
Pre requisite : None

LECTURER’S INFORMATION:

Name : DR. ROSMILAH BINTI MISNAN

E-mail : rosmilah@fsmt.upsi.edu.my
Telephone no. : 015-48117367
Room no. : Lecturer Room (Professor Madya 19), Level 3, Blok 01 KSAS

Name : PROF MADYA DR. NORJAN YUSOF

E-mail : norjan@fsmt.upsi.edu.my
Telephone no. : 015-48117370
Room no. : Lecturer Room (Professor Madya 18), Level 3, Blok 01 KSAS

Name : DR. HANISOM ABDULLAH

E-mail : hanisom@fsmt.upsi.edu.my
Telephone no. : 015-48117324
Room no. : Lecturer Room (Professor Madya 17), Level 3, Blok 01 KSAS

COURSE SYNOPSIS :

This course discusses the basic chemical reactions in cells at the molecular level. It includes
biomolecules, enzymes, and metabolism of carbohydrate, lipid, amino acids and
nucleotides. Enzyme characteristics and factors influence its kinetics will be discussed.
Catabolism and anabolism processes and their applications in life are also discussed. Basic
biochemical reactions in photosynthesis, aerobic and anaerobic metabolisms are included.

RATIONAL OF THE COURSE:

To provide students with the basic concepts in Biochemistry.

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LEARNING OUTCOMES:

1. Explain and illustrate biomolecules (C2).

2. Observe and conclude the reactions occur in a metabolism pathway (C5).

3. Design a mini project and carry out experiments to prove certain principles in
biochemistry. (C5, P4)

4. Relate the products from metabolism and justify the interrelationships between them
(C5).

5. Develop skills in team work during laboratory work and mini projects. (TS3, A2)

6. Reflect the importance of principles in biochemistry in regulating organism

metabolism. (A3, P4)

TRANSFERABLE SKILLS:

Skills in this course are developed through laboratory experiments and tutorial discussion.
Skills are assessed through coursework including report and presentation/exhibition the
product of the mini project.

REFERENCES:

1. Campbell, MK, Farrell, S.O. (2011). Biochemistry. 7th Edition. Belmont, California:
Cengage Learning.
2. Garret, R.H., & Grisham, C.M. (2010). Biochemistry (4th Ed.). Boston: Brooks/Cole,
Cengage Learning.
3. Moran, L.A., Horton, H.R., Scrimgeour, G. & Perry, M.D. (2011). Principles of
Biochemistry. New Jersey: Prentice Hall.

METHODS OF SOFT SKILLS EMBEDDED

Activity KOM BKMM PBPM KKBP KKU KKP EM

Laboratory work 

Mini project

Abbreviation Skills
KOM Communication Skill
BKMM Critical Thinking and Problem Solving Skills
PBPM Continuous Learning and Information Management
KKBP Team Work Skills
KKU Entrepreneurial Skills
KKP Leadership Skill
EM Professional Ethics and Moral

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STUDENT’S PERFORMANCE ASSESSMENT

Course work Percentage

Details LO %
Assignment 1: Laboratory Report LO1, LO2, LO3, LO4, LO5, LO6 15%
Assignment 2: Tutorial LO1, LO2, LO4, LO6 10% 60%
Assignment 3: Mini project LO1, LO2, LO3, LO4, LO5, LO6 15 %
Test 1 LO1, LO2, LO4, LO6 10%
Test 2 LO1, LO2, LO4, LO6 10%
Final exam LO1, LO2, LO4, LO6 40% 40%

Total 100%

GRADING SCALE:

Grade Points interval GPA/CGPA

A 80 – 100 4.00
A- 75 – 79 3.75
B+ 70 – 74 3.50
B 65 – 69 3.00
B- 60 – 64 2.75
C+ 55 – 59 2.50
C 50 – 54 2.00
C- 45 – 49 1.75
D+ 40 – 44 1.50
D 35 – 39 1.00
F 0 – 34 0

SOFT SKILS GRADING SCALE:

Scale
4 Excellent
3 Good
2 Moderate
1 Weak

Rubrics as in Buku Kemahiran Insaniah/Soft skills

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WEEK TEACHING SCHEDULE:

*Abbreviation Activity Abbreviation Assessment

L Lecture and Discussion L Test 1, Test 2, Final Exam
LW Laboratory Work LW Laboratory Report
A Assignment A Assignment Report
T Test T Test

*Optional

Week Chapter/Topic Learning Soft skills Learning & Teaching Activities Assessment
outcomes
At the end
of each
week, the
students
should be
able to:
Briefing on course outline,
Attendance and Assessment scheme)
& Explain An Introduction to SBK
1013 Introduction to Biochemistry.

1.0 Biomolecules LO1 PSK  Lecture

1.1 Functional groups of organic  Discussion
biomolecules  Week 1: Mini Project Nucleic
1 Tutorial
1.2 Major classes of biomolecules Acid)- start Test 1

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2.0 Biochemical processes LO1, PSK  Lecture
2.1 Biochemical reactions LO6  Discussion
2.2 Energy
2 2.2.1 Thermodynamic Tutorial
2.2.2 Free energy Test 1
2.2.3 Coupled reaction
2.2.4 Oxidation-reduction
reactions
2.3 Role of ATP
3.0 Water chemistry PSK  Lecture
3-4 3.1 Molecular structure of water LO1, LO2,  Discussion
3.1.1 Covalent bonds LO5, LO6  Week 3: Practical 1 (Acid base)
3.1.2 Hydrogen bonds  Week 4: Practical 2 (Water
3.2 Thermal properties of water Tutorial
properties)
3.3 Solvent properties of water Test 1
3.4 Density of water Lab report
3.5 Cohesion and adhesion of water
1.6 Ionization of water
1.6.1 Acids, Base and pH
3.6.2 Buffers
Mid Sem Break-1 week (4/7 – 10/7/2015)

PSK  Lecture
4.0 Enzymes LO1, LO3,
5-6 4.1 Properties of enzymes  Discussion
LO5, LO6 Tutorial
4.2 Classification of enzymes  Week 5: Practical 3 (Enzymes)
Test 2
4.3 Enzyme kinetics  Week 6: Practical 4 (Carbohydrate) Lab reort
4.4 Enzyme inhibition

Test 1 (Week 6)- TOPIC 1,2,3

7-8 PSK  Lecture
5.0 Nucleic acid LO1, LO2,  Discussion Tutorial
5.1 DNA and RNA LO4, LO6  Week 7: Practical 5 (Lipid) Test 2
5.2 Biosynthesis of DNA: replication  Week 8: Practical 6 (Protein) Mini Project
5.3 Biosynthesis of RNA: transcription
5.4 Protein Synthesis: translation

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6.0 Carbohydrate PSK  Lecture
 Discussion
7.1 Classes of carbohydrate LO1, LO2,
 Week 9-10: Mini Project Nucleic
7.1.1 Monosaccharide LO3, LO4,
7.1.2 Disaccharide LO5, LO6 acids- Presentation and
9-10 7.1.3 Polysaccharide submission
7.2 Carbohydrate metabolism
7.2.1 Glycolysis Tutorial
7.2.2 Glycogenesis Final Exam
7.2.3 Glycogenolysis Lab report
7.2.4 Gluconeogenesis
7.2.5 Pentose phosphate pathway
7.3 Aerobic respiration
7.3.1 Citric acid cycle
7.3.2 Electron transport chain
7.4 Anaerobic respiration

Test 2 (Week 11)- TOPIC 4,5

PSK  Lecture
7.0 Lipid  Discussion
11-12 LO1, LO2,
8.1 Lipid classes  Week 11 and 12: Practical 7 (Food
8.1.1 Fatty acids LO3, LO4,
LO5, LO6 Analysis)
8.1.2 Triacylglycerols Tutorial
8.2 Lipid metabolism Final Exam
8.2.1 Fatty acid degradation Lab report
8.2.2 Fatty acid biosynthesis
8.2.3 Cholesterol synthesis
8.2.4 Transport of lipids in
blood
8.0 Protein PSK  Lecture
13-14  Discussion
8.1 Amino acids structure LO1, LO2,
8.2 Amino acids classes LO3, LO4, Tutorial
8.3 Nitrogen metabolism LO5, LO6 Final Exam
8.4 Amino acid anabolism Lab report
8.5 Amino acid catabolism
8.6 Urea synthesis

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TUTORIAL/LAB/WORKSHOP PLAN

No Topic Learning Outcome Soft skill Learning & Teaching Activities Assessment

1 Acid Base Laboratory Practical

LO1, LO2, LO3, LO4, LO5, LO6 KKBP Lab Report
Observation, Scientific method, Team work
2 Water properties Laboratory Practical
LO1, LO2, LO3, LO4, LO5, LO6 KKBP Lab Report
Observation, Scientific method, Team work
3 Enzyme Laboratory Practical
LO1, LO2, LO3, LO4, LO5, LO6 KKBP Lab report
Observation, Scientific method, Team work
4 Carbohydrate Laboratory Practical
LO1, LO2, LO3, LO4, LO5, LO6 KKBP Lab report
Observation, Scientific method, Team work
5 Lipid Laboratory Practical
LO1, LO2, LO3, LO4, LO5, LO6 KKBP Lab report
Observation, Scientific method, Team work
6 Protein Laboratory Practical Lab report
LO1, LO2, LO3, LO4, LO5, LO6 KKBP
Observation, Scientific method, Team work
7 Nucleic acids Mini project, Laboratory Practical Mini project
LO1, LO2, LO3, LO4, LO5, LO6 KKBP
Observation, Scientific method, Team work report
9 Biomolecules LO1, LO2, LO4, LO6 - Discussion Tutorial
10 Biochemical process LO1, LO2, LO4, LO6 - Discussion Tutorial
11 Water chemistry LO1, LO2, LO4, LO6 - Discussion Tutorial
12 Enzyme LO1, LO2, LO4, LO6 - Discussion Tutorial
13 Nucleic acid LO1, LO2, LO4, LO6 - Discussion Tutorial
14 Carbohydrate LO1, LO2, LO4, LO6 - Discussion Tutorial
15 Lipid LO1, LO2, LO4, LO6 - Discussion Tutorial
16 Protein LO1, LO2, LO4, LO6 - Discussion Tutorial

Reminder:
1. Students must attend all lectures, tutorials, laboratory, studio or other activities related to the course, including courses with no final
examination (perkara 4.1dan 4.3)
2. Student with attendance of less than 80% will not be allowed to sit for final examination. (perkara 4.2)
3. Perkara 4.1, 4.2 and 4.3 can be waived for students who suffer from health problems and must be certified by government or UPSI panel
clinic medical officer.
4. Student who has to represent UPSI/State/Country in activity that is directed by the government or UPSI, is required to obtain a
recommendation letter from the Dean and must be approved by the Academic Affairs Division.

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