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Unlocking The Prediction of Preeclampsia, A Widespread, Life-Threatening Pregnancy Complication
Unlocking The Prediction of Preeclampsia, A Widespread, Life-Threatening Pregnancy Complication
What is preeclampsia?
A disease occurring during pregnancy that impacts almost 1 in 20
women worldwide, preeclampsia represents a significant threat to
women’s health. The condition involves reduced blood flow through
the placenta and inadequate oxygen and nutrients for the foetus
which, if left undetected, can lead to serious health consequences
for both mother and baby. Globally, the condition causes 15% of all
premature births and 42% of all maternal deaths.2
References
1 Anderson, U.D., Olson, M.G., Kristensen, K.H., Åkerström, B., & Hansson, S.R. (2012) Review:
Biochemical markers to predict preeclampsia. Placenta. 33(suppl), S42-7.
2 Verlohren, S., Galindo, A., Schlembach, D., Zeisler, H., Herraiz, I., et al. (2010). An automated
method for the determination of the sFlt-1/PIGF ratio in the assessment of preeclampsia. Am J
Obstet Gynecol. 202(2), 161.e1-161.e11.
3 Klein, E., Schlembach, D., Ramoni, A., et al. (2016). Influence of the sFlt-1/PIGF ratio on
clinical decision-making in women with suspected preeclampsia. Plos ONE 11(5): e0156013.
doi:10.1371/journal.pone.0156013.
4 Zeisler, H., Llurba, E., Chantraine, F. et al. (2016). Predictive Value of the sFlt-1: PlGF Ratio in
Women with Suspected Preeclampsia. N Engl J Med. 374, 13-22.
5 Vatish, M., Strunz-McKendry, T., Hund, M., Allegranaz, D., Wolf, C., Smare, C. (2016).
sFIt/PIGF ratio test for pre-eclampsia: an economic assessment for the UK. Ultrasound in Obstet
Gynecol. 48(6):765-771