VIJUNGCO, ARISA MAE D.

BSN II BLOCK 5 GROUP 24

DRUG THERAPEUTIC INDICATIONS CONTRA DOSAGES ADVERSE AND PHARMACO PHARMACO NURSING
ACTIONS INDICATIONS SIDE EFFECTS DYNAMICS KINETICS CONSIDERATIONS
GENERIC Bactericidal:  Respiratory  Contraindic Adults  CNS: Cephalexin Absorption Assessment
NAME: Inhibits tract infections ated with 1–4 g/day in Headache, (also called Well absorbed  History: Penicillin or
cephalexin synthesis of caused by allergy to divided doses; dizziness, Cefalexin) is from the cephalosporin allergy,
(sef a lex' in) bacterial cell Streptococcus cephalospor 250 mg PO q lethargy, a first upper pregnancy, or
wall, causing pneumoniae, ins or 6 hr usual paresthesias generation gastrointestin lactation
BRAND: cell death. group A beta- penicillins. dose. cephalosporin al tract with  Physical: Renal
Apo-Cephalex hemolytic  Skin and  GI: Nausea, antibiotic. It is nearly 100% function tests,
(CAN), Biocef, streptococci  Use skin vomiting, one of the oral respiratory status,
Keflex, Novo- cautiously structure diarrhea, most widely bioavailability skin status; culture
Lexin (CAN),  Skin and skin with renal infections: anorexia, prescribed . Cephalexin and sensitivity tests of
Nu-Cephalex structure failure, 500 mg PO abdominal pain, antibiotics, is not infected area
(CAN) infections lactation, q 12 hr. flatulence, often used for absorbed in
caused by pregnancy. Larger pseudomembran the treatment the stomach Interventions
staphylococcus, doses may ous colitis, of superficial but is  Arrange for culture
CLASSI- streptococcus be needed hepatotoxicity infections that absorbed in and sensitivity tests of
FICATION: in severe result as the upper infection before and
Pregnancy  Otitis media cases; do  GU: complications intestine. during therapy if
Category B caused by S. not exceed Nephrotoxicity of minor infection does not
pneumoniae, 4 g/day. wounds or Volume of resolve.
Antibiotic Haemophilus  Hematologic: lacerations. It
Bone marrow distribution  Give drug with meals;
influenzae, Pediatric is effective
depression 5.2-5.8L. arrange for small,
streptococcus, Patients against most
Cephalosporin frequent meals if GI
staphylococcus, 25–50 gram-positive
(first gen.)  Hypersensitivit Protein complications occur.
Moraxella mg/kg/day PO bacteria
catarrhalis y: Ranging through its binding
in divided  Refrigerate
from rash to inihibition of Cephalexin is
doses. suspension, discard
 Bone infections fever to the cross 10-15%
 Skin and after 14 days.
caused by anaphylaxis; linking bound to
skin
staphylococcus, serum sickness reaction serum
structure Teaching points
Proteus reaction between N- protein, inclu
infections:  Take this drug with
mirabilis acetyl ding serum
Divide  Other: food. Refrigerate
total daily muramicacid albumin.
 GU infections Superinfections and N- suspension; discard
dose, and any drug after 14
caused by acetylglucosa Metabolism
give q 12 days.
Escherichia mine in the
hr. Dosage Cephalexin is
coli, P. cell wall,  Complete the full
may be not
mirabilis, leading to cell course of this drug
doubled in metabolized
Klebsiella lysis. even if you feel better.
severe in the body.
cases.  This drug is
 Otitis Route of prescribed for this
media: 75– elimination particular infection;
100 Cephalexin is do not self-treat any
mg/kg/day
VIJUNGCO, ARISA MAE D. BSN II BLOCK 5 GROUP 24
PO in four over 90% other infection.
divided excreted in
doses. the urine after  You may experience
6 hours by these side effects:
glomerular Stomach upset, loss of
filtration and appetite, nausea (take
tubular drug with food);
secretion with diarrhea; headache,
a mean dizziness.
urinary
recovery of  Report severe
99.3%. diarrhea with blood,
Cephalexin is pus, or mucus; rash or
unchanged in hives; difficulty
the urine. breathing; unusual
tiredness, fatigue;
unusual bleeding or
bruising.

 Avoid alcohol while

taking cephalexin.