BD Phoenix Automated

TM

Microbiology
Giving you confidence in accurate detection of
antimicrobial resistance
 BD Phoenix panels menu

BD Phoenix Emerge
extended AST-only panels
• Wide selection of drugs and serial
two-fold dilutions for many
key antibiotics
• Embedded detection of resistance
markers BD Phoenix
Combo and AST-only
• Multiple combinations of Gram-negative
and Gram-positive panels to fit
different needs
• Most products available in ID / AST
and AST-only format
• Embedded detection of resistance
BD Phoenix markers
Combo and AST-only
• Gram negative fermenters and
non-fermenters panels
• Two formats of Gram-positive panels for
Enterococcus and Staphylococcus
• Available in combo (ID / AST) and AST-
only format In line with Clinical & Laboratory
Standards Institute (clsi.org) and
• Embedded detection of resistance
European Antimicrobial
markers
Susceptibility testing guidelines
(www.eucast.org)

ID: Identification
AST: Antimicrobial Susceptibility Testing
Combo: Combined ID and AST
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Accurate detection of antimicrobial resistances
with new drugs and concentrations

_
Highlights:
Gram-negative panels +
Highlights:
Gram-positive panels

Penicillin Cephalosporin
Amoxicillin / Clavulanate up to 32 / 16 µg / ml for SIR Ceftaroline: an advanced-generation cephalosporin that has
determination of bacteria responsible for bactericidal activity against Gram-positive pathogens
uncomplicated UTI including MRSA strains

Carbapenem Tigecycline
Lower concentrations allow easier detection of non- Activity against a wide variety of Gram-positive including
susceptible carbapenem organisms and resistances of multidrug-resistant strains1
clinical and / or epidemiological importance

• Ertapenem and Imipenem range starting from 0,25 µg

• Meropenem starting from 0,125 µg in line with the

screening cut-off proposed by EUCAST

Tigecycline
First member of the glycylcycline and increasingly used for
the treatment of multidrug-resistant organisms

2
 BD Phoenix Emerge Gram-positive

AST-only extended
panels raise confidence
in the detection of
antimicrobial resistance
• More drugs and wide range of serial
two-fold dilutions for many key antibiotics
• Real MIC detection and rapid AST results
• The BDXpertTM system and BD
EpiCenterTM systems for better
detection, expertise and real-time
communication

3
The more we offer, the safer you are

+
BD Phoenix Emerge Gram-positive BD Phoenix Emerge Gram-positive
448420 PMIC-84 448420 PMIC-84
μg / ml μg / ml
PENICILLIN OXAZOLIDNONES
Penicillin G 0.0625 - 8 Linezolid 2 - 16
Oxacillin 0.125 - 4 OTHER
Ampicillin 0.25 - 16 Mupirocin 0.5 - 4
β-LACTAM COMBINATION AGENT Mupirocin High level 256
Amoxicillin-Clavulanate 2/1 - 8/4 Fusidic Acid 0.5 - 8
CEPHEMS Pristinamycin 0.25 - 2
Cefazolin 2-8 Inducible macrolide resistance test YES
Cefoxitin 2-8
GLYCOPEPTIDES
Vancomycin 0.5 - 16
Teicoplanin 1 - 16
LIPOPEPTIDES
Daptomycin 0.5 - 4
AMINOGLYCOSIDE
Gentamicin 0.5 - 8
Gentamicin Synergy 500
Streptomycin Synergy 1000
MACROLIDES
Erythromycin 0.25 - 4
TETRACYCLINES
Doxycycline 0.5 - 4
FLUOROQUINOLONES
Ciprofloxacin 0.5 - 2
Moxifloxacin 0.25 - 2
Norfloxacin 1 - 16
NITROFURAN
Nitrofurantoin 32 - 128
LINCOSAMIDES
Clindamycin 0.125 - 4
FOLATE PATHWAY
ANTAGONISTS
Trimethoprim 0.5 - 8
Trimethoprim-Sulfamethoxazole 0.5 / 9.5 - 8 / 152
PHENICOLS
Chloramphenicol 1 - 16
ANSAMYCINS
Rifampin 0.25 - 8
FOSFOMYCINS
Fosfomycin w/G6P 16 - 64
STREPTOGRAMINS
Quinupristin-dalfopristin 0.5 - 4

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 BD Phoenix Gram-negative
CPO Detect
Discover how the BD
Select the best formulations PhoenixTM CPO detect
to meet your needs. test can
•D
 etect Carbapenemase Producing
Organisms quickly, efficiently
and accurately

• Classify CPOs within Ambler

classes A,B or D

•F
 acilitate rapid implementation of

CP
infection prevention and control
measures

• Support selection of targeted

antibiotic treatment for
CPO infections

Combating CPOs
critical threat:
BD PhoenixTM CPO detect.
The new, innovative BD PhoenixTM CPO
detect test is the first CPO detection test
on an automated ID/AST system that
reliably detects carbapenemases.
The test flags CPOs and classifies them
into main Ambler classes A, B, or D in 6 to
11 hours from isolated colonies. *As the
test is integrated in BD PhoenixTM panels,
#
susceptibility results for relevant drugs
such as Carbapenems, Tigecycline,
^
Colistin and Ceftazidime/Avibactam
will follow shortly after CPO detect
results are available.

* Time to results are 6H for Enterobacteriaceae and Acinetobacter, 11H for

Pseudomonas. Resultson file at BD.
#
CPO detect test is available in two formats: Yes/No and Yes/No plus Ambler
classification enabling its integration within different panel types.
^
Colistin is not available for testing in the US.

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BD Phoenix Emerge Gram-negative
CPO Detect
_ _
BD Phoenix Emerge Gram-Negative CLSI BD Phoenix Emerge Gram-Negative EUCAST
449023 NMIC-500 449025 NMIC-502
μg / ml μg / ml
PENICILLIN PENICILLIN
Ampicillin 4 -16 Ampicillin 2-8
β-LACTAM COMBINATION AGENT Piperacillin 4 - 64
Ampicillin - Sulbactam 4 / 2 - 16 / 8 Mecillinam 2-8
Ceftazidime - Avibactam 0.25 / 4 - 8 / 4 Temocillin 4 - 32
Piperacillin - Tazobactam 4 / 4 - 64 / 4 β-LACTAM COMBINATION AGENT
CEPHEMS Amoxicillin - Clavulanate 2 / 2 - 32 / 2
Cefazolin 2 - 16 Ceftazidime - Avibactam 0.25 / 4 - 8 / 4
Cefepime 1 - 16 Piperacillin - Tazobactam 4 / 4 - 64 / 4
Ceftriaxone 0.5 - 4 CEPHEMS
Cefoxitin 4 - 16 Cephalexin 4 - 16
Cefuroxime 4 - 16 Cefepime 1 - 16
Ceftazidime 0.5 - 16 Ceftriaxone 0.5 - 4
MONOBACTAMS Cefuroxime 2-8
Aztreonam 1 - 16 Ceftazidime 0.5 - 8
CARBAPENEMS Cefixime 0.5 - 2
Ertapenem 0.25 - 1 MONOBACTAMS
Imipenem 0.25 - 8 Aztreonam 1 - 16
Meropenem 0.25 - 32 CARBAPENEMS
LIPOPEPTIDES Ertapenem 0.25 - 1
Colistin 1-4 Imipenem 0.25- 8
AMINOGLYCOSIDES Meropenem 0.125 - 8
Gentamicin 2-8 LIPOPEPTIDES
Amikacin 4 - 32 Colistin 0.5 - 2
TETRACYCLINES AMINOGLYCOSIDES
Tetracycline 2 - 16 Gentamicin 1-4
Minocycline 1 - 16 Amikacin 4 - 16
Tigecycline 1-4 Tobramycin 1-4
FLUOROQUINOLONES TETRACYCLINES
Ciprofloxacin 0.06 - 2 Tigecycline 0.5 - 2
Levofloxacin 1-4 FLUOROQUINOLONES
Norfloxacin 2-8 Ciprofloxacin 0.06 - 1
FOLATE PATHWAY ANTAGONISTS Levofloxacin 0.5 - 2
Trimethoprim-Sulfamethoxazole 0.5 / 9.5 - 2 / 38 FOLATE PATHWAY ANTAGONISTS
FOSFOMYCINS Trimethoprim-Sulfamethoxazole 1 / 19 - 4 / 76
Fosfomycin w/G6P 16 - 128 FOSFOMYCINS
NITROFURAN Fosfomycin w/G6P 16 - 128
Nitrofurantoin 32 - 128 NITROFURAN
OTHER Nitrofurantoin 16 - 64
CPO detect YES OTHER
CPO detect Ambler class (E + P + A) YES CPO detect YES
ESBL YES CPO detect Ambler class (E + P + A) YES
ESBL YES

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 BD Phoenix Gram-positive panels
+ BD Phoenix Combo Gram-positive
448911 PMIC/ID-55
μg / ml
448614 PMIC/ID-95
μg / ml
PENICILLIN
Penicillin G 0.0625 - 0.25 0.0625 - 8
Oxacillin 0.25 - 2 0.25 - 4
Ampicillin 2-8 2-8
β-LACTAM COMBINATION AGENT
Amoxicillin-Clavulanate 1 / 0.5 - 4 / 2 -
CEPHEMS
Cefoxitin 2-8 2-8
GLYCOPEPTIDES
Vancomycin 1 - 16 1 - 16
Teicoplanin 1 - 16 1 - 16
LIPOPEPTIDES
Daptomycin - 1-4
AMINOGLYCOSIDES
Amikacin 8 - 32 -
Gentamicin 1-8 2-8
Gentamicin Synergy 500 500
Tobramycin 2-8 -
MACROLIDES
Erythromycin 0.25 - 4 0.25 - 4
TETRACYCLINES
Tetracycline 0.5 - 8 0.5 - 8
Minocycline - 1-8
Doxycycline - 0.5 - 8
FLUOROQUINOLONES
Ciprofloxacin 0.25 - 4 0.5 - 2
Levofloxacin - 1-4
NITROFURAN
Nitrofurantoin 16 - 64 16 - 64
LINCOSAMIDES
Clindamycin 0.5 - 2 0.5 - 2
FOLATE PATHWAY ANTAGONISTS
Trimethoprim 0.5 - 2 -
Trimethoprim-Sulfamethoxazole 1 / 19 - 4 / 76 1 / 19 - 4 / 76
ANSAMYCINS
Rifampin 0.5 - 2 -
STREPTOGRAMINS
Quinupristin-dalfopristin 0.5 - 2 0.5 - 2
OXAZOLIDNONES
Linezolid 0.5 - 4 1-4
OTHER
Mupirocin 1-4 -
Mupirocin High level 256 -
Fusidic Acid 1-8 1-8
Inducible macrolide resistance test YES YES
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BD Phoenix Gram-negative panels
_ BD Phoenix Combo Gram-negative
CPO - EUCAST CPO - CLSI
449026 NMIC/ID-503 449027 NMIC/ID-504 448505 NMIC/ID-4 448783 NMIC/ID-95
μg / ml μg / ml μg / ml μg / ml
PENICILLIN
Ampicillin 2-8 4 - 16 4 - 16 4 - 16
Piperacillin - - 4 - 64 -
Temocillin 4 - 32 - - -
β-LACTAM COMBINATION AGENT
Ceftazidime - Avibactam 0.25 / 4 - 8 / 4 0.25 / 4 - 8 / 4 - -
Amoxicillin - Clavulanate 2 / 2 - 32 / 2 - 4 / 2 - 16 / 8 4 / 2 - 16 / 8
Ampicillin - Sulbactam - 4 / 2 - 16 / 8 4 / 2 - 16 / 8 -
Piperacillin - Tazobactam 4 / 4 - 16 / 4 4 / 4 - 64 / 4 4 / 4 - 64 / 4 4 / 4 - 64 / 4
CEPHEMS
Cefazolin - 2 - 16 4 - 16 -
Cefepime 1-8 1 - 16 2 - 16 1 - 16
Ceftriaxone 1-4 1-4 - 1 - 16
Cefotaxime - - 1 - 32 -
Cefoxitin - - - 4 - 16
Cefuroxime 2-8 - - 4 - 16
Ceftazidime 1-8 2 - 16 1 - 16 2 - 16
Cephalothin - - - 4 - 16
MONOBACTAMS
Aztreonam - - 2 - 16 2 - 16
CARBAPENEMS
Ertapenem 0.25 - 1 0.25 - 1 - 0.25 - 1
Imipenem 0.25 - 8 0.25 - 8 1-8 1-8
Meropenem 0.125 - 8 0.5 - 16 1-8 1-8
LIPOPEPTIDES
Colistin 1-4 1-4 0.5 - 2 1-4
AMINOGLYCOSIDES
Gentamicin 1-4 2-8 2-8 2-8
Amikacin 4 - 16 8 - 32 8 - 32 -
Tobramycin - - - 2-8
TETRACYCLINES
Minocycline - 1-8 - -
Tigecycline 0.5 - 2 1-4 - -
Tetracycline - - 2-8 -
FLUOROQUINOLONES
Ciprofloxacin 0.25 - 1 0.125 - 2 0.5 - 2 0.5 - 2
Levofloxacin 0.5 - 2 - 1-8 -
Norfloxacin - - - 2-8
Moxifloxacin - - 1-4 -
FOLATE PATHWAY ANTAGONISTS
Trimethoprim - - - 1-8
Trimethoprim-Sulfamethoxazole 1 / 19 - 4 / 76 1 / 19 - 4 / 76 0.5 / 9.5 - 2 / 38 0.5 / 9.5 - 2 / 38
PHENICOLS
Chloramphenicol - - 4 - 16 4 - 16
NITROFURAN
Nitrofurantoin - - - 16 - 64
OTHER
ESBL YES YES YES YES
CPO detect YES YES - - 8
 Gram-negative Gram-positive
Cat Number Description Cat Number Description
Gram-negative Gram-negative
BD Phoenix CPO Combo panels* BD Phoenix CPO Combo panels*
(ID + AST) (ID + AST)
449026 NMIC/ID-503 EUCAST 448911 PMIC/ID-55
449027 NMIC/ID-504 CLSI 448614 PMIC/ID-95
BD Phoenix CPO Emerge panels* BD Phoenix Emerge panels*
(AST) (AST)
449023 NMIC-500 CLSI 448420 PMIC-84
449025 NMIC-502 EUCAST
BD Phoenix Combo panels*
(ID + AST)
448505 NMIC/ID-4 CLSI
448783 NMIC/ID-95 CLSI

BD Phoenix system is CE marked in compliance to the European IVD Directive 98/79/EC

1. Greer ND. Tigecycline (Tygacil): the first in the glycylcycline class of antibiotics. Proc (Bayl Univ Med Cent).
2006;19(2):155-161.
2. Woodford et al, Comparison of BD Phoenix, Vitek 2, and MicroScan Automated Systems for Detection of inference
of Mechanisms Responsible for Carbapenem Resistance in Enterobacteriaceae. JCM 2010. 48(8):2999-3002.

* Panel availability subjected to local regulatory authorities approval and configuration may be subjected to change.
Please consult your BD representative for the local panel options.

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