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SAFETY DATA SHEET

Version 5.4
Revision Date 22.06.2018
Print Date 04.05.2019

1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

1.1 Product identifiers
Product name : Ethanol
Product Number : 16368
Brand : Sigma-Aldrich
1.2 Other means of identification
No data available
1.3 Relevant identified uses of the substance or mixture and uses advised against
For R&D use only. Not for pharmaceutical, household or other uses.
1.4 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Pte Ltd
1 Science Park Road
#02-14 The Capricorn
Singapore Science Park Road II
SINGAPORE 117528
SINGAPORE

Telephone : +65 6779 1200

Fax : +65 6779 1822
1.5 Emergency telephone number
Emergency Phone # : 1-800-262-8200

2. HAZARDS IDENTIFICATION
2.1 GHS Classification
Flammable liquids (Category 2)
Serious eye damage/eye irritation (Category 2)
2.2 GHS Label elements, including precautionary statements

Pictogram

Signal word Danger

Hazard statement(s)
H225 Highly flammable liquid and vapour.
H319 Causes serious eye irritation.
Precautionary statement(s)
Prevention
P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ ventilating/ lighting/ equipment.
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 P280 Wear protective gloves/ eye protection/ face protection.
Response
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing.
Rinse skin with water/shower.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to
extinguish.
Storage
P403 + P235 Store in a well-ventilated place. Keep cool.
Disposal
P501 Dispose of contents/ container to an approved waste disposal plant.
2.3 Other hazards - none

3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance / Mixture : Substance
3.1 Substances
Hazardous components
Component Classification Concentration
Ethanol
Flam. Liq. 2; 2A; H225, H319 <= 100 %
For the full text of the H-Statements mentioned in this Section, see Section 16.

4. FIRST AID MEASURES

4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water.
Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
irritant effects, respiratory paralysis, Dizziness, narcosis, inebriation, euphoria, Nausea, Vomiting
4.3 Indication of any immediate medical attention and special treatment needed
No data available

5. FIREFIGHTING MEASURES
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
No data available
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.

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5.4 Further information
Use water spray to cool unopened containers.

6. ACCIDENTAL RELEASE MEASURES

6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation.
Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form
explosive concentrations. Vapours can accumulate in low areas.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and
place in container for disposal according to local regulations (see section 13).
6.4 Reference to other sections
For disposal see section 13.

7. HANDLING AND STORAGE

7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic
charge.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
7.3 Specific end use(s)
No data available

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

8.1 Control parameters
Occupational Exposure Limits
Component CAS-No. Value Control Basis
parameters
Ethanol 64-17-5 PEL 1,000 ppm Singapore. Workplace Safety and Health
(long 1,880 mg/m3 Act - First Schedule Permissible Exposure
term) Limits of Toxic Substances
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at
the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the
standard EN 374 derived from it.
Full contact
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 Material: butyl-rubber
Minimum layer thickness: 0.3 mm
Break through time: 480 min
Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.2 mm
Break through time: 38 min
Material tested:Dermatril® P (KCL 743 / Aldrich Z677388, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test
method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,
contact the supplier of the CE approved gloves. This recommendation is advisory only and must be
evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated
use by our customers. It should not be construed as offering an approval for any specific use
scenario.
Body Protection
Impervious clothing, Flame retardant antistatic protective clothing., The type of protective equipment
must be selected according to the concentration and amount of the dangerous substance at the
specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with
multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to
engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).

9. PHYSICAL AND CHEMICAL PROPERTIES

9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid, clear
Colour: colourless
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing Melting point/range: -114 °C - lit.
point
f) Initial boiling point and 78 °C - lit.
boiling range
g) Flash point 14.0 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower Upper explosion limit: 19 %(V)
flammability or Lower explosion limit: 3.3 %(V)
explosive limits
k) Vapour pressure 59.5 hPa at 20.0 °C
l) Vapour density No data available
m) Relative density 0.789 g/cm3 at 25 °C
n) Water solubility completely soluble
o) Partition coefficient: n- log Pow: -0.349 at 24 °C
octanol/water
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 p) Auto-ignition 363.0 °C
temperature
q) Decomposition No data available
temperature
r) Viscosity No data available

10. STABILITY AND REACTIVITY

10.1 Reactivity
No data available
10.2 Chemical stability
No data available
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
Heat, flames and sparks.
10.5 Incompatible materials
Alkali metals, Oxidizing agents, Peroxides
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides
Other decomposition products - No data available

11. TOXICOLOGICAL INFORMATION

11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - male and female - 10,470 mg/kg
LC50 Inhalation - Rat - male and female - 4 h - 124.7 mg/l
LC50 Inhalation - Rat - 4 h - 30,000 mg/l
Skin corrosion/irritation
Skin - Rabbit - No skin irritation - OECD Test Guideline 404
Serious eye damage/eye irritation
Eyes - Rabbit - Causes serious eye irritation. - OECD Test Guideline 405
Respiratory or skin sensitisation
Sensitisation test: - negative
Remarks: (IUCLID)
Germ cell mutagenicity
Genotoxicity in vitro - Ames test - Salmonella typhimurium - with and without metabolic activation - negative
Genotoxicity in vitro - In vitro mammalian cell gene mutation test - Mouse lymphoma test - with and without
metabolic activation - negative
Genotoxicity in vivo - Mouse - male - Oral
Carcinogenicity
Carcinogenicity - Mouse - Oral
Tumorigenic:Equivocal tumorigenic agent by RTECS criteria. Liver:Tumors. Blood:Lymphomas including
Hodgkin's disease.
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Reproductive toxicity - Human - female - Oral
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 Effects on Newborn: Apgar score (human only). Effects on Newborn: Other neonatal measures or effects.
Effects on Newborn: Drug dependence.
Specific target organ toxicity - single exposure
Specific target organ toxicity - repeated exposure
Aspiration hazard
No data available
Potential health effects
Inhalation May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes Causes serious eye irritation.
Signs and Symptoms of Exposure
irritant effects, respiratory paralysis, Dizziness, narcosis, inebriation, euphoria, Nausea, Vomiting
Additional Information
RTECS: KQ6300000

12. ECOLOGICAL INFORMATION

12.1 Toxicity
Toxicity to fish flow-through test LC50 - Pimephales promelas (fathead minnow) - 15.3 mg/l -
96 h
Toxicity to daphnia and LC50 - Ceriodaphnia dubia (water flea) - 5,012 mg/l - 48 h
other aquatic
invertebrates
NOEC - Daphnia magna (Water flea) - 9.6 mg/l - 9 d
Toxicity to algae EC50 - Chlorella vulgaris (Fresh water algae) - 275 mg/l - 72 h
Method: OECD Test Guideline 201
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 15 d
Result: 95 % - Readily biodegradable.
Method: OECD Test Guideline 301E
12.3 Bioaccumulative potential
Due to the distribution coefficient n-octanol/water, accumulation in organisms is not expected.
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
No data available
12.6 Other adverse effects
No data available

13. DISPOSAL CONSIDERATIONS

13.1 Waste treatment methods
Product
Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as
this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal
company.
Contaminated packaging
Dispose of as unused product.

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14. TRANSPORT INFORMATION
14.1 UN number
ADR/RID: 1170 IMDG: 1170 IATA-DGR: 1170
14.2 UN proper shipping name
ADR/RID: ETHANOL
IMDG: ETHANOL
IATA-DGR: Ethanol
14.3 Transport hazard class(es)
ADR/RID: 3 IMDG: 3 IATA-DGR: 3
14.4 Packaging group
ADR/RID: II IMDG: II IATA-DGR: II
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA-DGR: no
14.6 Special precautions for user
No data available

15. REGULATORY INFORMATION

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Notification status
AICS: On the inventory, or in compliance with the inventory
DSL: All components of this product are on the Canadian DSL
ENCS: On the inventory, or in compliance with the inventory
IECSC: On the inventory, or in compliance with the inventory
ISHL: On the inventory, or in compliance with the inventory
KECI: On the inventory, or in compliance with the inventory
NZIoC: On the inventory, or in compliance with the inventory
PICCS: On the inventory, or in compliance with the inventory

16. OTHER INFORMATION

Text of H-code(s) and R-phrase(s) mentioned in Section 3
Skin Corr. Skin corrosion
Further information
Copyright 2016 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use
only.
The above information is believed to be correct but does not purport to be all inclusive and shall be used
only as a guide. The information in this document is based on the present state of our knowledge and is
applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held
liable for any damage resulting from handling or from contact with the above product. See www.sigma-
aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

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