previous LLETZ procedures. All but one woman had a laparoscopic
abdominal cerclage performed prior to pregnancy. There was one laparotomy with abdominal cerclage at 9 weeks gestation. Of the 12 pregnancies, there were 11 liveborn infants. One woman had a first trimester miscarriage, which was managed with misoprostol. The median age of delivery was 38+3 weeks and the mean birthweight was 3188 grams. Most (9/11) were delivered by elective cesarean section; however two (18%) were delivered preterm by emergency cesarean section at 34 and 36 weeks for preterm prelabour rupture of membranes and contractions. CONCLUSION: In carefully selected population, there is a high success rate of transabdominal cerclage.
536 Cerclage suture type: provider preference or
does it matter? Ashley N. Battarbee, Josh Ellis, Tracy A. Manuck University of North Carolina School of Medicine, Chapel Hill, NC OBJECTIVE: Prior studies have evaluated whether braided or non- braided suture material influences outcomes post-cerclage, with mixed results. We sought to evaluate whether pregnancy outcomes vary by the thickness of suture material. STUDY DESIGN: Retrospective cohort study at a single tertiary care center, 2013-2016. Women with a singleton, non-anomalous gestation who underwent cervical cerclage placement during pregnancy were included. We evaluated those with history-indi- cated cerclages (prophylactic, after 1 prior mid-trimester preg- nancy losses suggestive of cervical insufficiency), transvaginal ultrasound (TVUS)-indicated cerclages (unplanned, for cervical length <25mm and history of prior PTB), and exam-indicated cerclages (unplanned, due to mid-trimester cervical dilation). Outcomes were analyzed by type of suture material, comparing thinner polyester braided thread (EthibondÒ) and polypropylene non-braided monofilament (ProleneÒ) to thicker 5mm braided polyester fiber suture (MersileneÒ tape). The primary outcome was PTB<37 weeks. RESULTS: 214 women met inclusion criteria; 128 (60%) with thicker Mersilene tape and 86 (40%) with thinner EthibondÒ or ProleneÒ suture. Overall, 141 had history-indicated, 35 TVUS- indicated, and 38 exam-indicated cerclages. The majority (69%) were McDonald cerclages. 100 (47%) delivered <37 weeks. De- mographics and baseline characteristics are shown in the Table. Women with unplanned cerclage (TVUS-indicated, exam-indi- cated) were less likely to have Mersilene suture (Table). However, among women with unplanned cerclage, those with Mersilene had lower rates of PTB <37 weeks (Figure). Improvements in median delivery GA were also seen for those with Mersilene (37.7 weeks, IQR 34.7-39) vs. Ethibond/Prolene (32.5 weeks, IQR 27.9-36.3), p<0.001. Rates of composite neonatal morbidity (NEC, grade 3/4 IVH, BPD, death) were also lower in the Mersilene group (9% vs. 21%, p¼0.017). In regression models, Mersilene tape (aOR 0.51, 95% CI 0.27-0.96, p¼0.037) and unplanned cerclage timing (aOR 1.87, 95% CI 1.02-3.43, p¼0.044) were associated with PTB <37 weeks. CONCLUSION: Rates of PTB are high in women with cervical cerclage placed in pregnancy. Though placement of the thicker Mersilene tape is less common for unplanned cerclages, its use in this high risk subset is associated with later delivery gestational ages and lower rates of PTB.
S320 American Journal of Obstetrics & Gynecology Supplement to JANUARY 2018