Decision Tree for Oral Mucosa Lesions Geographic tongue (erythema migrans)

(Revised 3/08)
Hairy tongue
Leukoedema
White sponge nevus
Epithelial thickening Hairy leukoplakia
Lichen planus
Nicotinic stomatitis
Candidosis Hyperkeratosis
Surface debris Epithelial dysplasia
Burn Carcinoma-in-situ
White Squamous cell carcinoma
Congenital keratotic cysts
Subepithelial Scar
Fordyce granules

Hemangioma
Surface Intravascular Varix Epidermolysis bullosa
Lesions of Kaposi’s sarcoma
Oral Mucosa Extravasated Hematoma Primary herpes
blood Ecchymosis Herpes simplex Recurrent herpes
Localized Petechiae Herpangina
Melanocytic Oral melanotic macule Hand, foot and mouth disease
Nevus Herpes zoster
Tattoo Melanoma Hereditary Infectious mononucleosis Erosive lichen planus
Pigmented Ephelis Varicella (Chickenpox) Mucous membrane pemphigoid
Hereditary Viral Pemphigus vulgaris
Addison’s disease Bullous pemphigoid
Heavy metal ingestion Lupus erythematosus
Generalized Peutz-Jeghers syndrome Autoimmune Aphthous ulcers
Clinical Neurofibromatosis Erythema multiforme Epithelial dysplasia
Impression Polyostotic fibrous dysplasia Erythroplasia (erythroplakia) Carcinoma in situ
Pregnancy Idiopathic Medication-Induced mucositis Squamous cell carcinoma
Medication Contact stomatitis
Smoker’s melanosis
Vesicular-ulcerated- Mycotic Candidosis
erythematous Parulis/sinus track
Periodontal abscess Papilloma
Mucocele (mucous extravasation phenomenon) Verruca vulgaris
Reactive Fibrous hyperplasia Condyloma acuminatum
Inflammatory papillary hyperplasia Irritation fibroma
Necrotizing sialometaplasia Fibroma Epulis fissuratum
Peripheral ossifying fibroma
Soft Tissue Epithelial Leiomyoma
Enlargements Benign Mesenchymal Rhabdomyoma
Salivary gland Pleomorphic adenoma Peripheral giant cell granuloma
Papillary cystadenoma lymphomatosum Hemangioma
Gingival cyst of adult Adenoid cystic carcinoma Lymphangioma
Tumor or Cysts Lymphoepithelial cyst Acinic cell adenocarcinoma Pyogenic granuloma
Neoplasm Epidermoid/dermoid cyst Mucoepidermoid carcinoma, low grade Lipoma
Thyroglossal tract cyst Polymorphous low-grade adenocarcinoma Neuroma
Monomorphic adenoma Neurofibroma
Squamous cell carcinoma Schwannoma
Malignant Verrucous carcinoma Granular cell tumor
Lymphoma Congenital epulis
Metastatic carcinoma Adenoid cystic carcinoma
Melanoma Mucoepidermoid carcinoma
Sarcoma Polymorphous low-grade adenocarcinoma
Salivary gland adenocarcinoma Acinic cell adenocarcinoma
©2008 University of Iowa, College of Dentistry