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Introduction in Hospital Radiopharmacy
Introduction in Hospital Radiopharmacy
RADIOPHARMACY?
YES !!!
no !!!
radiopharmaceuticals - how radionuclide bind target molecule
Radiopharmaceutical Radionuclide
Binding and localization in organs or lesions - range of processes that are part of
the ADME principles
Radionuclide – gamma emitter
Radiopharmaceutical
imaging
(Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH-R)
Literature
Definition: Radiopharmacy
Diagnostic Therapeutic
Graves' disease,
Hyperthyroidism
Radiolabeled somatostatin
analogues are used for the
treatment of neuroendocrine
tumors
Ongoing investigative studies:
Primary bone cancers
Ovarian cancer
Using innovative means (e.g., targeting agents) to deliver the drug to the
tumor.
Radiopharmaceuticals have been used
as tracers of physiologic processes.
Advantage:
Allows non-invasive external monitoring or targeted therapeutic irradiation
with very little effect on the biologic processes in the body.
Site-specific targeting:
Allows the physician to treat widely disseminated diseases.
Radioactivity