Progetti di ricerca disponibili per il Dottorato di Ricerca in Genetica e Biologia Molecolare XXXIV ciclo

Title: Dissecting the role of the long non-coding RNA Charme in skeletal and cardiac
myogenesis Proponent: Monica Ballarino Affiliation: Department of Biology and Biotechnology "Charles Darwin",
Sapienza University of Rome.

Title: New therapeutic approaches for the therapy of Duchenne Muscular Dystrophy, Proponent: Irene
Bozzoni, Affiliation: Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome

Title: Role of RNA modifications in motor neuron differentiation and related diseases, Proponent: Irene
Bozzoni, Affiliation: Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome
and CNLS@Uniroma of IIT

Title: Role of noncoding RNAs in regulatory networks underlying neuronal differentiation and pathology.
Proponent: Elisa Caffarelli, Affiliation: Istitute of Molecular Biology and Pathology of CNR at Department of Biology
and Biotechnology "Charles Darwin", Sapienza University of Rome.

Title: Investigating a causal interaction between stress and aging Proponent: Laura Fanti Affiliation:
Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome.

Title: Physiology, pathology and therapy in aging, Proponent: Isabella Saggio, Affiliation: Department of Biology
and Biotechnology "Charles Darwin", Sapienza University of Rome.

Title:Analysis of the DM2 pathogenic mechanisms using Drosophila as model system. Proponent: Laura
Ciapponi, Dept of Biology and Biotechnologies, Charles Darwin, Sapienza University of Rome

Title: Forensic genetic analysis of geographical ancestry in African populations.Proponent: Fulvio

Cruciani Affiliation: Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome

Title: Molecular networks in developmental boundary formation Proponent: Sabrina Sabatini Affiliation:
Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome.

Title: Computational studies to delineate intein-mediated protein splicing mechanism. Proponent: Domenico
Raimondo Affiliation: Department of Molecular Medicine, Sapienza University of Rome.

Title: Common Fragile Sites and genome instability Proponent: Franca Pelliccia, Department of Biology and
Biotechnology. franca.pelliccia@uniroma1.it

Title: Genetic basis of plant root cortical variability: an evolutive problem and a biotechnological
opportunity. Proponent: Sabrina Sabatini/Raffaele dello Ioio Department of Biology and Biotechnology “Charles
Darwin” – Polo San Lorenzo, Via dei Sardi 70, Roma, Italy

Title: Investigating the role of N6-methyladenosine modification in acute myeloid

leukemia Proponent: Alessandro Fatica Affiliation: Department of Biology and Biotechnology "Charles Darwin",
Sapienza University of Rome.

Title: A diachronic analysis of central Italy as traced by modern and ancient genomes: The genetic legacy of
the Roman Empire. Proponent: Beniamino Trombetta Affiliation: Department of Biology and Biotechnology "Charles
Darwin", Sapienza University of Rome.

Title: Connecting DNA repair and metabolic alterations of obesity in a search for predictive biomarkers. Proponent:
Francesca Marcon, Affiliation: Istituto Superiore di Sanità

Title: Investigating the role of cell cycle regulators in the control of skeletal muscle function and
pathophysiology. Proponent: Maurizia Caruso. Affiliation: CNR – Institute of Cell Biology and Neurobiology, Rome
Title: Golgi phosphoprotein 3 and membrane trafficking in cytokinesis and cell proliferation. Proponent: Maria
Grazia Giansanti Affiliation: Consiglio Nazionale delle Ricerche, Istituto di Biologia e Patologia molecolari

Title: Human induced pluripotent stem cell neural model from Joubert Syndrome for the study of ciliopathy-
associated molecular mechanisms. Proponent: Jessica Rosati, Cellular Reprogramming Unit. Affiliation: CSS-
MENDEL, IRCCS Casa Sollievo della Sofferenza