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IV.

Pathophysiology

Modifiable Factors
> sedentary lifestyle Non-modifiable Factors:
> high intake of fats and cholesterol > Female
> low fiber intake > 52 years old
> being overweight
> alcohol consumption

supersaturation of bile with


cholesterol and calcium

precipitation of solute from


solution and become crystals

crystals come together and fuse to


become calculi

passes thru the bile duct


gallstones causing obstruction

abdominal pain in the


right upper quadrant cholelithiasis choledocholithiasis
pain scale: 9/10

biliary colic distention of the


gallbladder obstructive jaundice

venous & lymphatic localized cellular


drainage are impaired infiltration
yellowish discoloration
of eyes and skin
proliferation of bacteria ischemia

cholecystitis

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