IMMUNOLOGY- PART 2

1.Peptides Derived from cytosolic proteins are bound to

a. Class I MHC
b. Class II MHC
c. Class I and II MHC
d. Class III MHC
e. All the above

2.The functional role of IgM is

a. Initiates the Differentiation of B-cells
b. Release Histamines by Mast cell
c. Protects from Proteolysis
d. Both A and B
e. None of the above

3.---------- Enzyme is absent in Myeloma cells

a. HGRPT
b. HGTRP
c. HGPRT
d. HPGRP
e. None of the above

4.Macrophages generally kill the bacteria they phagocytose by fusing lysosomes containing digestive
enzymes with the phagocytic vesicle. In the case of pathogens which block this fusion, pathogen killing
can still be achieved through the effector function of

a. B cells.
b. complement.
c. cytotoxic T cells.
d. opsonizing antibody.
e. Th1 cells.

5. Phagocytosis

a. can be stimulated by antigen binding to complement or antibody.

b. is an antigen-specific process.
c. must be preceded by antigen processing.
d. rids the body of virus-infected cells.
e. only occurs after plasma cells begin secreting antibody.

Common data Questions for 6 and 7

several friends who went on a picnic together developed vomiting and diarrhea from eating potato salad
contaminated with Staphylococcus aureus enterotoxin.

6. Effects of the toxin could best be counteracted by

a. antibody binding and neutralization of the toxin.

b. antibody opsonization and phagocytosis of S. aureus.
c. antibody opsonization and phagocytosis of the toxin.
d. B cell binding to S. aureus.
e. cytotoxic T cell binding and lysis of S. aureus.

7. The vomiting caused by Staphylococus Enterotoxin is an example of

a. Surface Antigens
b. Super Antigens
c. Surface Markers
d. Both A and B

8. A molecule that can be covalently linked to a non-immunogenic antigen to make it an immunogen is

called
a. adjuvant.
b. carrier.
c. hapten.
d. mitogen.
e. superantigen.

9. An antibody Fab contains

a. complementarity determining regions.
b. H and L chain variable regions.
c. one antigen binding region.
d. one H-L interchain disulfide bond.
e. all of the above.

10.The antigen-binding region of TCR is formed by the folding of

a. Va and Vb chains.
b. Va, Vb, and CD3 chains.
c. Va and Vb2-microglobulin chains.
d. Vg and Va chains.
e. VL and VH chains.
11.Exogenous antigen is processed

a. after presentation by antigen presenting cells.

b. by nearly every nucleated cell.
c. by the cytosolic processing pathway.
d. in the presence of b2-microglobulin.
e. in acidified endosomes.