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UGC - B.Sc. Life Sciences - New PDF
UGC - B.Sc. Life Sciences - New PDF
UGC - B.Sc. Life Sciences - New PDF
1
Details of Courses
1. Animal Diversity
2. Comparative Anatomy and Developmental Biology of Vertebrates
3. Physiology and Biochemistry
4. Genetics and Evolutionary Biology
1. Applied Zoology
2. Animal Biotechnology
3. Aquatic Biology
4. Immunology
5. Reproductive Biology
6. Insect, Vector and Diseases
Core Courses-Chemistry
1. Conceptual Organic Chemistry
2. Molecules of Life
3. Chemical Bonding
4. Physical Chemistry for the Biosciences
2
Discipline Specific Electives-Chemistry (Any two)
1. Environmental Science
2. English/MIL Communication
Botany
1. Biofertilizers
2. Herbal Technology
3. Nursery and Gardening
4. Floriculture
5. Medicinal Botany
6. Plant Diversity and Human Welfare
7. Ethnobotany
8. Mushroom Culture Technology
9. Intellectual Property Rights
Chemistry
Zoology
3
1. Apiculture
2. Aquarium Fish Keeping
3. Aquatic Biology
4. Medical Diagnostics
5. Public Health and Hygiene
5. Sericulture
4
Scheme of B.Sc. Life Sciences under CBCS
5
Core Course Botany -II Practical Plant Ecology and 2
Taxonomy
6
Skill Enhancement Course-I SEC-I 2
7
VI Discipline Specific Elective DSE Botany II 4
Botany -II
Total: 120
8
Core Course: Botany
Paper I
Biodiversity (Microbes, Algae, Fungi and Archegoniate)
THEORY
Lectures: 60
Viruses – Discovery, general structure, replication (general account), DNA virus (T-phage);
Lytic and lysogenic cycle, RNA virus (TMV); Economic importance; Bacteria – Discovery,
General characteristics and cell structure; Reproduction – vegetative, asexual and recombination
(conjugation, transformation and transduction); Economic importance.
9
Unit 5: Bryophytes (10 Lectures)
General characteristics, classification, Early land plants (Cooksonia and Rhynia). Classification
(up to family), morphology, anatomy and reproduction of Selaginella, Equisetum and Pteris.
(Developmental details not to be included). Heterospory and seed habit, stelar evolution.
Ecological and economical importance of Pteridophytes.
Practical
7. Gram staining
9. Rhizopus and Penicillium: Asexual stage from temporary mounts and sexual structures
through permanent slides.
12. Agaricus: Specimens of button stage and full grown mushroom; Sectioning of gills of
Agaricus.
13. Lichens: Study of growth forms of lichens (crustose, foliose and fruticose)
15. Marchantia- morphology of thallus, w.m. rhizoids and scales, v.s. thallus through
gemma cup, w.m. gemmae (all temporary slides), v.s. antheridiophore, archegoniophore,
l.s. sporophyte (all permanent slides).
16. Funaria- morphology, w.m. leaf, rhizoids, operculum, peristome, annulus, spores
(temporary slides); permanent slides showing antheridial and archegonial heads, l.s.
capsule and protonema.
17. Selaginella- morphology, w.m. leaf with ligule, t.s. stem, w.m. strobilus, w.m.
microsporophyll and megasporophyll (temporary slides), l.s. strobilus (permanent slide).
18. Equisetum- morphology, t.s. internode, l.s. strobilus, t.s. strobilus, w.m. sporangiophore,
w.m. spores (wet and dry)(temporary slides); t.s rhizome (permanent slide).
19. Pteris- morphology, t.s. rachis, v.s. sporophyll, w.m. sporangium, w.m. spores
(temporary slides), t.s. rhizome, w.m. prothallus with sex organs and young sporophyte
(permanent slide).
20. Cycas- morphology (coralloid roots, bulbil, leaf), t.s. coralloid root, t.s. rachis, v.s. leaflet,
v.s. microsporophyll, w.m. spores (temporary slides), l.s. ovule, t.s. root (permanent
slide).
21. Pinus- morphology (long and dwarf shoots, w.m. dwarf shoot, male and female), w.m.
dwarf shoot, t.s. needle, t.s. stem, , l.s./t.s. male cone, w.m. microsporophyll, w.m.
microspores (temporary slides), l.s. female cone, t.l.s. & r.l.s. stem (permanent slide).
Suggested Readings
1. Kumar, H.D. (1999). Introductory Phycology. Affiliated East-West. Press Pvt. Ltd. Delhi.
11
2nd edition.
2. Tortora, G.J., Funke, B.R., Case, C.L. (2010). Microbiology: An Introduction, Pearson
Benjamin Cummings, U.S.A. 10th edition.
3. Sethi, I.K. and Walia, S.K. (2011). Text book of Fungi & Their Allies, MacMillan
Publishers Pvt. Ltd., Delhi.
5. Raven, P.H., Johnson, G.B., Losos, J.B., Singer, S.R., (2005). Biology. Tata McGraw
Hill, Delhi, India.
6. Vashishta, P.C., Sinha, A.K., Kumar, A., (2010). Pteridophyta, S. Chand. Delhi, India.
7. Bhatnagar, S.P. and Moitra, A. (1996). Gymnosperms. New Age International (P) Ltd
Publishers, New Delhi, India.
12
Core Course Botany
Paper–II
Plant Ecology and Taxonomy
THEORY
Lectures: 60
Soil: Origin, formation, composition, soil profile. Water: States of water in the environment,
precipitation types. Light and temperature: Variation Optimal and limiting factors; Shelford law
of tolerance. Adaptation of hydrophytes and xerophytes.
Structure; energy flow trophic organisation; Food chains and food webs, Ecological pyramids
production and productivity; Biogeochemical cycling; Cycling of carbon, nitrogen and
Phosphorous
Functions of Herbarium, important herbaria and botanical gardens of the world and India;
Documentation: Flora, Keys: single access and multi-access
data. (6 Lectures)
13
Unit 9 Taxonomic hierarchy (2 Lectures)
Principles and rules (ICN); ranks and names; binominal system, typification, author citation,
valid publication, rejection of names, principle of priority and its limitations.
Types of classification-artificial, natural and phylogenetic. Bentham and Hooker (upto series),
Engler and Prantl (upto series).
Characters; variations; OTUs, character weighting and coding; cluster analysis; phenograms,
cladograms (definitions and differences).
Practical
5. Determination of minimal quadrat size for the study of herbaceous vegetation in the college
campus by species area curve method. (species to be listed)
6. Quantitative analysis of herbaceous vegetation in the college campus for frequency and
comparison with Raunkiaer’s frequency distribution law
7. Study of vegetative and floral characters of the following families (Description, V.S. flower,
section of ovary, floral diagram/s, floral formula/e and systematic position according to
Bentham & Hooker’s system of classification):Brassicaceae -Brassica, Alyssum / Iberis;
Asteraceae -Sonchus/Launaea, Vernonia/Ageratum, Eclipta/Tridax; Solanaceae -Solanum
nigrum, Withania; Lamiaceae -Salvia, Ocimum; Liliaceae - Asphodelus / Lilium / Allium.
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8. Mounting of a properly dried and pressed specimen of any wild plant with herbarium
label (to be submitted in the record book).
Suggested Readings
1. Kormondy, E.J. (1996). Concepts of Ecology. Prentice Hall, U.S.A. 4th edition.
2. Sharma, P.D. (2010) Ecology and Environment. Rastogi Publications, Meerut, India. 8th
edition.
3. Simpson, M.G. (2006). Plant Systematics. Elsevier Academic Press, San Diego, CA, U.S.A.
4. Singh, G. (2012). Plant Systematics: Theory and Practice. Oxford & IBH Pvt. Ltd., New
Delhi. 3rd edition.
15
Core Course Botany
Paper-III
Plant Anatomy and Embryology
THEORY
Lectures: 60
Vascular cambium – structure and function, seasonal activity. Secondary growth in root and
stem, Wood (heartwood and sapwood).
Structure of anther and pollen; Structure and types of ovules; Types of embryo sacs,
organization and ultrastructure of mature embryo sac.
Endosperm types, structure and functions; Dicot and monocot embryo; Embryo-
endosperm relationship.
16
Unit 8: Apomixis and polyembryony (8 Lectures)
Practical
3. Stem: Monocot: Zea mays; Dicot: Helianthus; Secondary: Helianthus (only Permanent
slides).
4. Root: Monocot: Zea mays; Dicot: Helianthus; Secondary: Helianthus (only Permanent
slides).
7. Structure of anther (young and mature), tapetum (amoeboid and secretory) (Permanent
slides).
11. Pollination types and seed dispersal mechanisms (including appendages, aril, caruncle)
(Photographs and specimens).
17
Suggested Readings
18
Core Course Botany
Paper-IV
Plant Physiology and Metabolism
(Credits: Theory-4, Practicals-2)
THEORY
Lectures: 60
Importance of water, water potential and its components; Transpiration and its significance;
Factors affecting transpiration; Root pressure and guttation.
Composition of phloem sap, girdling experiment; Pressure flow model; Phloem loading and
unloading.
19
Biological nitrogen fixation; Nitrate and ammonia assimilation.
Photoperiodism (SDP, LDP, Day neutral plants); Phytochrome (discovery and structure), red
and far red light responses on photomorphogenesis; Vernalization.
Practical
2. To study the effect of two environmental factors (light and wind) on transpiration by
excised twig.
5. Demonstrate the activity of catalase and study the effect of pH and enzyme
concentration.
6. To study the effect of light intensity and bicarbonate concentration on O2 evolution in
photosynthesis.
1. Bolting.
4. R.Q.
20
5. Respiration in roots.
Suggested Readings
1. Taiz, L., Zeiger, E., (2010). Plant Physiology. Sinauer Associates Inc., U.S.A. 5th
Edition.
2. Hopkins, W.G., Huner, N.P., (2009). Introduction to Plant Physiology. John Wiley &
Sons, U.S.A. 4th Edition.
21
Discipline Specific Elective Botany
THEORY
Lectures: 60
The Cell Theory; Prokaryotic and eukaryotic cells; Cell size and shape; Eukaryotic Cell
components.
DNA: Miescher to Watson and Crick- historic perspective, Griffith’s and Avery’s
transformation experiments, Hershey-Chase bacteriophage experiment, DNA structure, types of
DNA, types of genetic material.
Types of structures of RNA (mRNA, tRNA, rRNA), RNA polymerase- various types;
Translation (Prokaryotes and eukaryotes), genetic code.
Practical
1. To study prokaryotic cells (bacteria), viruses, eukaryotic cells with the help of light and
electron micrographs.
2. Study of the photomicrographs of cell organelles
3. To study the structure of plant cell through temporary mounts.
4. To study the structure of animal cells by temporary mounts-squamous epithelial cell and
nerve cell.
5. Preparation of temporary mounts of striated muscle fiber
6. To prepare temporary stained preparation of mitochondria from striated muscle cells /cheek
epithelial cells using vital stain Janus green.
7. Study of mitosis and meiosis (temporary mounts and permanent slides).
8. Study the effect of temperature, organic solvent on semi permeable membrane.
9. Demonstration of dialysis of starch and simple sugar.
10. Study of plasmolysis and deplasmolysis on Rhoeo leaf.
11. Measure the cell size (either length or breadth/diameter) by micrometry.
12. Study the structure of nuclear pore complex by photograph (from Gerald Karp)Study of
special chromosomes (polytene & lampbrush) either by slides or photographs.
13. Study DNA packaging by micrographs.
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14. Preparation of the karyotype and ideogram from given photograph of somatic metaphase
chromosome.
Suggested Readings
1. Karp, G. 2010. Cell and Molecular Biology: Concepts and Experiments. 6th Edition.
John Wiley & Sons. Inc.
2. De Robertis, E.D.P. and De Robertis, E.M.F. 2006. Cell and Molecular Biology. 8th
edition. Lippincott Williams and Wilkins, Philadelphia.
3. Cooper, G.M. and Hausman, R.E. 2009. The Cell: A Molecular Approach. 5th edition.
ASM Press & Sunderland, Washington, D.C.; Sinauer Associates, MA.
4. Becker, W.M., Kleinsmith, L.J., Hardin. J. and Bertoni, G. P. 2009. The World of the
Cell. 7th edition. Pearson Benjamin Cummings Publishing, San Francisco.
24
Discipline Specific Elective Botany
Economic Botany and Biotechnology
THEORY
Lectures: 60
General account with special reference to clove and black pepper (Botanical name, family, part
used, morphology and uses)
Blotting techniques: Northern, Southern and Western Blotting, DNA Fingerprinting; Molecular
DNA markers i.e. RAPD, RFLP, SNPs; DNA sequencing, PCR and Reverse Transcriptase-
PCR. Hybridoma and monoclonal antibodies, ELISA and Immunodetection. Molecular
diagnosis of human disease, Human gene Therapy.
Practical
1. Study of economically important plants : Wheat, Gram, Soybean, Black pepper, Clove
Tea, Cotton, Groundnut through specimens, sections and microchemical tests
Suggested Readings
1. Kochhar, S.L. (2011). Economic Botany in the Tropics, MacMillan Publishers India
Ltd., New Delhi. 4th edition.
2. Bhojwani, S.S. and Razdan, M.K., (1996). Plant Tissue Culture: Theory and Practice.
Elsevier Science Amsterdam. The Netherlands.
3. Glick, B.R., Pasternak, J.J. (2003). Molecular Biotechnology- Principles and
Applications of recombinant DNA. ASM Press, Washington.
26
Discipline Specific Elective Botany
Analytical Techniques in Plant Sciences
THEORY
Lectures: 60
Unit 3: Radioisotopes
Unit 4: Spectrophotometry
Practicals
27
1. Study of Blotting techniques: Southern, Northern and Western, DNA fingerprinting,
DNA sequencing, PCR through photographs.
2. Demonstration of ELISA.
Suggested Readings
3. Ausubel, F., Brent, R., Kingston, R. E., Moore, D.D., Seidman, J.G., Smith, J.A.,
Struhl, K. (1995). Short Protocols in Molecular Biology. John Wiley & Sons. 3rd
edition.
4. Zar, J.H. (2012). Biostatistical Analysis. Pearson Publication. U.S.A. 4th edition.
28
Discipline Centric Elective Botany
Bioinformatics
THEORY
Lectures: 60
National Center for Biotechnology Information (NCBI): Tools and Databases of NCBI,
Database Retrieval Tool, Sequence Submission to NCBI, Basic local alignment search tool
(BLAST), Nucleotide Database, Protein Database, Gene Expression Database.
DNA Data Bank of Japan (DDBJ): Introduction, Resources at DDBJ, Data Submission at
DDBJ.
Protein Information Resource (PIR): About PIR, Resources of PIR, Databases of PIR, Data
Retrieval in PIR.
29
Structural Bioinformatics in Drug Discovery, Quantitative structure-activity relationship
(QSAR) techniques in Drug Design, Microbial genome applications, Crop improvement.
Practical
3. Sequence alignment.
Suggested Readings
30
Discipline Centric Elective Botany
Research Methodology
THEORY
Lectures: 60
Common calculations in botany laboratories. Understanding the details on the label of reagent
bottles. Molarity and normality of common acids and bases. Preparation of solutions. Dilutions.
Percentage solutions. Molar, molal and normal solutions. Technique of handling micropipettes;
Knowledge about common toxic chemicals and safety measures in their handling.
History; Key biology research areas, Model organisms in biology (A Brief overview): Genetics,
Physiology, Biochemistry, Molecular Biology, Cell Biology, Genomics, Proteomics-
Transcriptional regulatory network.
Numbers, units, abbreviations and nomenclature used in scientific writing. Writing references.
Powerpoint presentation. Poster presentation. Scientific writing and ethics, Introduction to
copyright-academic misconduct/plagiarism.
Practical
Suggested Readings
2. Stapleton, P., Yondeowei, A., Mukanyange, J., Houten, H. (1995). Scientific writing for
agricultural research scientists – a training reference manual. West Africa Rice
Development Association, Hong Kong.
3. Ruzin, S.E. (1999). Plant microtechnique and microscopy. Oxford University Press,
New York, U.S.A.
32
Core Course Chemistry: 1
Conceptual Organic Chemistry
(Credits: Theory-4, Practicals-2)
THEORY
Lectures: 60
Optical Isomerism: Optical activity, specific and molar rotation, chirality, enantiomerism,
diastereoisomerism, racemic mixtures and their resolution by salt formation method.
Name reactions: Aldol, cross Aldol, Claisen, Knoevengel, Cannizzaro, cross Cannizzaro
Free radical substitution reactions: Halogenation of alkanes, allylic compounds and alkyl
benzenes.
33
Nucleophilic substitution reactions: Alkyl, allyl and benzyl halides – substitution of halogen
by some common nucleophiles. Mechanism of SN1 and SN2 reactions (stereochemistry, nature
of substrate, nucleophile and leaving group)
Aldehydes: Oxidation with potassium permanganate, chromic acid and Tollen’s reagent
Ketones: Oxidation with potassium permanganate, sodium hypoiodite (iodoform reaction) and
Baeyer–Villiger oxidation
Aldeydes and Ketones: Catalytic hydrogenation, reduction with sodium borohydride, lithium
aluminium hydride, Clemmensen, Wolff-Kishner
Carboxylic acids and their derivatives: Lithium aluminium hydride, sodium-ethanol and
Rosenmund reduction.
34
Nitro compounds: Acidic, alkaline and neutral reducing agents, lithium aluminium hydride and
electrolytic reduction.
Recommended Texts:
1. I. L. Finar: Organic Chemistry (Vol. I & II), E. L. B. S.
2. R. T. Morrison & R. N. Boyd: Organic Chemistry, Pearson Education.
3. Arun Bahl and B. S. Bahl : Advanced Organic Chemistry, S. Chand
4. Peter Sykes: A Guide Book to Mechanism in Organic Chemistry, Orient Longman.
5. Eliel, E. L. & Wilen, S. H. Stereochemistry of Organic Compounds; Wiley: London,
1994.
6. T. W. Graham Solomon’s Organic Chemistry, John Wiley and Sons.
7. P.S. Kalsi, Stereochemistry, Conformation and Mechanism, John Wiley and Sons.
8. D. Nasipuri, Stereochemistry of Organic Compounds, New Age International
Publishers.
35
PRACTICAL-1
Organic preparations: Carry out the following preparations using 0.5 - 1 g of starting
compound. Recrystallize the product and determine the melting point of the recrystallized
sample.
4. To prepare acetanilide by the acetylation of aniline.
5. To prepare p-bromoacetanilide.
6. Benzolyation of aniline or β-naphthol by Schotten-Baumann reaction
7. Hydrolysis of benzamide or ethyl bezoate.
8. Semicarbazone derivative of one the following compounds: acetone, ethyl methyl
ketone, diethylketone, cyclohexanone, benzaldehyde.
9. Nitration of nitrobenzene.
10. Oxidation of benzaldehyde by using alkaline potassium permanganate.
Recommended Texts:
1. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic
Chemistry, 5th Ed., Pearson (2012).
2. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, Longman, London & New
York.
3. Ahluwalia, V.K.; Dhingra, S. & Gulati, A. College Practical Chemistry, Universities
Press.
36
Core Course Chemistry-II
Molecules of Life
(Credits: Theory-4, Practicals-2)
THEORY
Lectures: 60
Mechanism of enzyme action, factors affecting enzyme action, Coenzymes and cofactors and
their role in biological reactions, Specificity of enzyme action (including stereospecificity),
Enzyme inhibitors and their importance, phenomenon of inhibition (competitive and non-
competitive inhibition including allosteric inhibition). Drug action - receptor theory. Structure –
activity relationships of drug molecules, binding role of –OH group, -NH2 group, double bond
and aromatic ring.
Components of Nucleic acids: Adenine, guanine, thymine and cytosine (structure only), other
components of nucleic acids, Nucleosides and nucleotides (nomenclature), Structure of
polynucleotides; Structure of DNA (Watson-Crick model) and RNA (types of RNA), Genetic
code, Biological roles of DNA and RNA: Replication, Transcription and Translation.
37
Oils and fats: Common fatty acids present in oils and fats, Omega fatty acids, Trans fats,
Hydrogenation, Saponification value, Iodine number.
Biological importance of triglycerides, phospholipids, glycolipids, and steroids (cholesterol).
Calorific value of food. Standard caloric content of carbohydrates, proteins and fats.
Oxidation of foodstuff (organic molecules) as a source of energy for cells. Introduction to
metabolism (catabolism, anabolism), ATP: the universal currency of cellular energy,
ATP hydrolysis and free energy change.
Conversion of food into energy. Outline of catabolic pathways of Carbohydrates - Glycolysis,
Fermentation, Krebs Cycle. Overview of catabolic pathways of fats and proteins.
Interrelationships in the metabolic pathways of proteins, fats and carbohydrates.
Recommended Texts:
1. Morrison, R. T. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd.
(Pearson Education).
2. Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd.
(Pearson Education).
3. Finar, I. L. Organic Chemistry (Volume 2), Dorling Kindersley (India) Pvt. Ltd.
(Pearson Education).
4. Nelson, D. L. & Cox, M. M. Lehninger’s Principles of Biochemistry 7th Ed., W. H.
Freeman.
5. Berg, J. M., Tymoczko, J. L. & Stryer, L. Biochemistry 7th Ed., W. H. Freeman.
PRACTICAL-2
Recommended Texts:
1. Furniss, B.S.; Hannaford, A.J.; Rogers, V.; Smith, P.W.G.; Tatchell, A.R. Vogel’s
Textbook of Practical Organic Chemistry, ELBS.
2. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry,
Universities Press.
38
Core Course Chemistry: III
CHEMICAL BONDING, TRANSITION METAL & COORDINATION CHEMISTRY
(Credits: Theory-4, Practicals-2)
THEORY
Lectures: 60
Unit 1: The covalent bond and the structure of molecules (10 Lectures)
Valence bond approach, Concept of resonance in various organic and inorganic compounds,
Hybridization and structure, equivalent and non-equivalent hybrid orbitals, Bent’s rule and its
applications, VSEPR model for predicting shapes of molecules and ions containing lone pairs,
sigma and pi bonds.
LCAO method, symmetry and overlap for s-s ,s-p and p-p combinations, MO treatment of
homonuclear diatomic molecules of 2nd period (B2, C2 ,N2, O2 , F2 ) and heteronuclear di-atomic
molecules (CO, NO) and their ions.
van der Waals forces, Hydrogen bonding and its applications, effects of these forces on melting
point, boiling point and solubility.
General group trends with special reference to electronic configuration, variable valency,
colour, magnetic and catalytic properties, ability to form complexes and stability of various
oxidation states (Latimer diagrams) for Mn, Fe and Cu.
Valence Bond Theory (VBT): Inner and outer orbital complexes of Cr, Fe, Co, Ni and Cu
(coordination numbers 4 and 6). Structural and stereoisomerism in complexes with coordination
numbers 4 and 6.
Coordination compounds in biological systems: Fe, Cu, Co, Mn, Ni, Zn and heavy metal ions.
39
Crystal field effect, octahedral symmetry. Crystal field stabilization energy (CFSE), Crystal
field effects for weak and strong fields. Tetrahedral symmetry. Factors affecting the magnitude
of D. Spectrochemical series. Comparison of CFSE for Oh and Td complexes, Tetragonal
distortion of octahedral geometry.
Suggested Texts:
1. James E. Huheey, “Inorganic Chemistry: Principles of structure and reactivity”,
Prentice Hall, IV Edition.
2. D. S. Shriver and P.A. Atkins, “Inorganic Chemistry”, Oxford University Press, IV
Edition.
3. Alan G. Sharpe, “Inorganic Chemistry”, University of Cambridge, III Edition.
4. J. D. Lee, “A New Concise Inorganic Chemistry”, ELBS IV Edition
5. Grey L. Miessler and Donald A. Tarr, “Inorganic Chemistry”, Prentice Hall, III Edition.
6. B. Douglas, D. H. McDaniel and J. J. Alexander, “Concepts and Models of Inorganic
Chemistry”, John Wiley and Sons, III Edition.
7. Rodgers, G.E. Inorganic & Solid State Chemistry, Cengage Learning India Ltd., 2008.
40
PRACTICAL-3
Titrimetric Analysis:
Preparations of standard solutions (concept of primary and secondary standards), Different units
of concentration (molarity, molality, normality and formality)
Recommended Texts:
1. Vogel, A.I. A Textbook of Quantitative Inorganic Analysis, ELBS.
2. Harris, D.C. & Freeman, W.H. & Co. Quantitative Chemical Analysis 7th Ed., New York.
41
Core Course Chemistry: IV
Physical Chemistry for the Biosciences
THEORY
Lectures: 60
Important principles and definitions of thermochemistry. Concept of standard state and standard
enthalpies of formation, integral and differential enthalpies of solution and dilution. Calculation
of bond energy, bond dissociation energy and resonance energy from thermochemical data.
Variation of enthalpy of a reaction with temperature – Kirchhoff’s equation.
Free energy change in a chemical reaction. Thermodynamic derivation of the law of chemical
equilibrium. Distinction between ΔG and ΔGo, Le Chatelier’s principle. Relationships between
Kp, Kc and Kx for reactions involving ideal gases.
Strong, moderate and weak electrolytes, degree of ionization, factors affecting degree of
ionization, ionization constant and ionic product of water. Ionization of weak acids and bases,
pH scale, common ion effect. Salt hydrolysis-calculation of hydrolysis constant, degree of
hydrolysis and pH for different salts. Buffer solutions. Solubility and solubility product of
sparingly soluble salts – applications of solubility product principle.
The concept of reaction rates. Effect of temperature, pressure, catalyst and other factors on
reaction rates. Order and molecularity of a reaction. Derivation of integrated rate equations for
zero and first order reactions. Half–life of a reaction. General methods for determination of
order of a reaction. Concept of activation energy and its calculation from Arrhenius equation.
Enzyme kinetics.
42
IR Spectroscopy: Fundamental and non-fundamental molecular vibrations, IR spectrum,
fingerprint and group frequency regions and their significance, Hooke’s law and vibrational
frequency. Factors affecting vibrational frequency.
Characterization of functional groups: alkanes, alkenes, alkynes (only alicyclic systems),
aldehydes, ketones, carboxylic acids and their derivatives, hydroxy compounds and amines.
Study of hydrogen bonding.
Electronic Spectroscopy: Electronic transitions, singlet and triplet states, dissociation and
predissociation.
UV spectroscopy: Types of electronic transitions, UV spectrum, λmax, εmax, chromophores,
auxochromes, bathochromic shift, hypsochromic shift (definitions and elementary examples)
and solvent effect. Characteristic UV transitions in common functional groups.
General applications of UV spectroscopy including distinction between cis-trans isomers.
Woodward rules for calculating λmax in the following systems:
Conjugated dienes: alicyclic, homoannular, heteroannular.
α,β-Unsaturated aldehydes and ketones.
Extended conjugated systems: dienes, aldehydes and ketones.
PMR spectroscopy: Basic principles of NMR spectroscopy, PMR scale, chemical shifts
(concept of shielding and deshielding), factors influencing chemical shifts, simple spin-spin
couplings, coupling constant, chemical shift equivalence, anisotropic effects in alkenes,
alkynes, aldehydes and aromatics. Interpretation of PMR spectra of simple compounds.
Recommended Texts:
1. Atkins, P. W. & Paula, J. de Atkin’s Physical Chemistry 9th Ed., Oxford University
Press (2011).
2. Ball, D. W. Physical Chemistry Thomson Press, India (2007).
3. Castellan, G. W. Physical Chemistry 4th Ed. Narosa (2004).
4. Mortimer, R. G. Physical Chemistry 3rd Ed. Elsevier: NOIDA, UP (2009).
5. Chang, R. Physical Chemistry for the Biosciences. University Science Books (2005).
PRACTICAL-4
(I) Thermochemistry
43
3. Determination of integral enthalpy of solution of salts (endothermic and exothermic).
4. Preparation of sodium acetate-acetic acid buffer solutions and measurement of their pH.
5. Potentiometric titrations of (i) strong acid vs strong base (ii) weak acid vs strong
base
6. Determination of dissociation constant of a weak acid.
(V) Colourimetry
9. Verification of Lambert-Beer's Law for potassium dichromate/ potassium permanganate
solution.
10. Determination of pK (indicator) for phenolphthalein.
11. Study the kinetics of interaction of crystal violet with sodium hydroxide colourimetrically.
Recommended Texts:
1. Khosla, B.D.; Garg, V.C.; Gulati, A. & Chand, R. Senior Practical Physical Chemistry,
New Delhi.
44
Discipline Specific Electives
Select two papers
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CHEMISTRY-DSE (ELECTIVES)
Sampling, evaluation of analytical data, errors, accuracy and precision, methods of their
expression, normal law of distribution if indeterminate errors, statistical test of data; F, Q and t
test, rejection of data, and confidence intervals.
(5 Lectures)
Optical methods of analysis:
Origin of spectra, interaction of radiation with matter, fundamental laws of spectroscopy and
selection rules, validity of Beer-Lambert’s law.
Basic principles of quantitative analysis: estimation of metal ions from aqueous solution,
geometrical isomers, keto-enol tautomers. Determination of composition of metal complexes
using Job’s method of continuous variation and mole ratio method.
(25 Lectures)
Thermal methods of analysis:
(5 Lectures)
Electroanalytical methods:
45
Classification of electroanalytical methods, basic principle of pH metric, potentiometric and
conductometric titrations. Techniques used for the determination of equivalence points.
Techniques used for the determination of pKa values.
(10 Lectures)
Separation techniques:
Qualitative and quantitative aspects of solvent extraction: extraction of metal ions from aqueous
solution, extraction of organic species from the aqueous and nonaqueous media.
Qualitative and quantitative aspects of chromatographic methods of analysis: IC, GLC, GPC,
TLC and HPLC.
(15 Lectures)
Reference Books:
Jeffery, G.H., Bassett, J., Mendham, J. & Denney, R.C. Vogel’s Textbook of
Quantitative Chemical Analysis, John Wiley & Sons, 1989.
Willard, H.H., Merritt, L.L., Dean, J. & Settoe, F.A. Instrumental Methods of Analysis,
7th Ed. Wadsworth Publishing Company Ltd., Belmont, California, USA, 1988.
Christian, G.D; Analytical Chemistry, 6th Ed. John Wiley & Sons, New York, 2004.
Harris, D. C. Exploring Chemical Analysis, Ed. New York, W.H. Freeman, 2001.
Khopkar, S.M. Basic Concepts of Analytical Chemistry. New Age, International
Publisher, 2009.
Skoog, D.A. Holler F.J. & Nieman, T.A. Principles of Instrumental Analysis, Cengage
Learning India Ed.
Mikes, O. Laboratory Hand Book of Chromatographic & Allied Methods, Elles
Harwood Series on Analytical Chemistry, John Wiley & Sons, 1979.
Ditts, R.V. Analytical Chemistry; Methods of Separation, van Nostrand, 1974.
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46
PRACTICALS- DSE LAB: ANALYTICAL METHODS IN CHEMISTRY
60 Lectures
I. Separation Techniques
1. Chromatography:
(ii) Separation and identification of the monosaccharides present in the given mixture (glucose
& fructose) by paper chromatography. Reporting the Rf values.
(b) Separate a mixture of Sudan yellow and Sudan Red by TLC technique and identify them on
the basis of their Rf values.
(c) Chromatographic separation of the active ingredients of plants, flowers and juices by TLC
(i) To separate a mixture of Ni2+ & Fe2+ by complexation with DMG and extracting the Ni2+-
DMG complex in chloroform, and determine its concentration by spectrophotometry.
(ii) Solvent extraction of zisconium with amberliti LA-1, separation from a mixture of irons and
gallium.
3. Determine the pH of the given aerated drinks fruit juices, shampoos and soaps.
4. Determination of Na, Ca, Li in cola drinks and fruit juices using flame photometric
techniques.
5. Analysis of soil:
6. Ion exchange:
(i) Determination of exchange capacity of cation exchange resins and anion exchange resins.
(iii) Separation of amino acids from organic acids by ion exchange chromatography.
III Spectrophotometry
47
1. Determination of pKa values of indicator using spectrophotometry.
Reference Books:
Jeffery, G.H., Bassett, J., Mendham, J. & Denney, R.C. Vogel’s Textbook of
Quantitative Chemical Analysis, John Wiley & Sons, 1989.
Willard, H.H., Merritt, L.L., Dean, J. & Settoe, F.A. Instrumental Methods of Analysis,
7th Ed. Wadsworth Publishing Company Ltd., Belmont, California, USA, 1988.
Christian, Gary D; Analytical Chemistry, 6th Ed. John Wiley & Sons, New York, 2004.
Harris, Daniel C: Exploring Chemical Analysis, Ed. New York, W.H. Freeman, 2001.
Khopkar, S.M. Basic Concepts of Analytical Chemistry. New Age, International
Publisher, 2009.
Skoog, D.A. Holler F.J. & Nieman, T.A. Principles of Instrumental Analysis, Cengage
Learning India Ed.
Mikes, O. Laboratory Hand Book of Chromatographic & Allied Methods, Elles
Harwood Series on Analytical Chemistry, John Wiley & Sons, 1979.
Ditts, R.V. Analytical Chemistry; Methods of Separation, van Nostrand, 1974.
-----------------------------------------------------------------------------------------------------------
(10 Lectures)
Force Fields:
(14 Lectures)
Minimization and related methods for exploring the energy surface. Non-derivative method,
First and second order minimization methods. Computer simulation methods. Simple
48
thermodynamic properties and Phase Space. Boundaries. Analyzing the results of a simulation
and estimating Errors.
(12 Lectures)
(12 Lectures)
(12 Lectures)
Reference Books:
Leach, A.R. Molecular Modelling Principles and Application, Longman, 2001.
Haile, J.M. Molecular Dynamics Simulation Elementary Methods, John Wiley and Sons,
1997.
Gupta, S.P. QSAR and Molecular Modeling, Springer - Anamaya Publishers, 2008.
---------------------------------------------------------------------------------------------------------------
49
aldehyde (c) ketone (d) amine (e) ether (f) nitrile (g) thiol (h) carboxylic acid (i) ester (j)
amide.
vii. (a) Determine the heat of hydration of ethylene. (b) Compute the resonance energy of
benzene by comparison of its enthalpy of hydrogenation with that of cyclohexene.
viii. Arrange 1-hexene, 2-methyl-2-pentene, (E)-3-methyl-2-pentene, (Z)-3-methyl-2-
pentene, and 2,3-dimethyl-2-butene in order of increasing stability.
ix. (a) Compare the optimized bond angles H2O, H2S, H2Se. (b) Compare the HAH bond
angles for the second row dihydrides and compare with the results from qualitative MO
theory.
Reference Books:
Leach, A.R. Molecular Modelling Principles and Application, Longman, 2001.
Haile, J.M. Molecular Dynamics Simulation Elementary Methods, John Wiley and Sons,
1997.
Gupta, S.P. QSAR and Molecular Modeling, Springer - Anamaya Publishers, 2008.
-----------------------------------------------------------------------------------------------------------
Literature Survey:
Digital: Web resources, E-journals, Journal access, TOC alerts, Hot articles, Citation index,
Impact factor, H-index, E-consortium, UGC infonet, E-books, Internet discussion groups and
communities, Blogs, Preprint servers, Search engines, Scirus, Google Scholar, ChemIndustry,
Wiki- Databases, ChemSpider, Science Direct, SciFinder, Scopus.
Information Technology and Library Resources: The Internet and World Wide Web.
Internet resources for chemistry. Finding and citing published information.
(20 Lectures)
Reporting practical and project work. Writing literature surveys and reviews. Organizing a
poster display. Giving an oral presentation.
50
(20 Lectures)
Safe working procedure and protective environment, protective apparel, emergency procedure
and first aid, laboratory ventilation. Safe storage and use of hazardous chemicals, procedure for
working with substances that pose hazards, flammable or explosive hazards, procedures for
working with gases at pressures above or below atmospheric – safe storage and disposal of
waste chemicals, recovery, recycling and reuse of laboratory chemicals, procedure for
laboratory disposal of explosives, identification, verification and segregation of laboratory
waste, disposal of chemicals in the sanitary sewer system, incineration and transportation of
hazardous chemicals.
(12 Lectures)
Data Analysis
The Investigative Approach: Making and Recording Measurements. SI Units and their use.
Scientific method and design of experiments.
Analysis and Presentation of Data: Descriptive statistics. Choosing and using statistical tests.
Chemometrics. Analysis of variance (ANOVA), Correlation and regression, Curve fitting,
fitting of linear equations, simple linear cases, weighted linear case, analysis of residuals,
General polynomial fitting, linearizing transformations, exponential function fit, r and its abuse.
Basic aspects of multiple linear regression analysis.
(13 Lectures)
Electronics
Basic fundamentals of electronic circuits and their components used in circuits of common
instruments like spectrophotometers, typical circuits involving operational amplifiers for
electrochemical instruments. Elementary aspects of digital electronics.
(10 Lectures)
Reference Books
Dean, J. R., Jones, A. M., Holmes, D., Reed, R., Weyers, J. & Jones, A. (2011)
Practical skills in chemistry. 2nd Ed. Prentice-Hall, Harlow.
Hibbert, D. B. & Gooding, J. J. (2006) Data analysis for chemistry. Oxford University
Press.
Topping, J. (1984) Errors of observation and their treatment. Fourth Ed., Chapman
Hall, London.
Harris, D. C. Quantitative chemical analysis. 6th Ed., Freeman (2007) Chapters 3-5.
Levie, R. de, How to use Excel in analytical chemistry and in general scientific data
analysis. Cambridge Univ. Press (2001) 487 pages.
Chemical safety matters – IUPAC – IPCS, Cambridge University Press, 1992.
OSU safety manual 1.01.
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51
CHEMISTRY-DSE: GREEN CHEMISTRY
(Credits: Theory-04, Practicals-02)
Theory: 60 Lectures
What is Green Chemistry? Need for Green Chemistry. Goals of Green Chemistry. Limitations/
Obstacles in the pursuit of the goals of Green Chemistry
(4 Lectures)
Twelve principles of Green Chemistry with their explanations and examples and special
emphasis on the following:
Green solvents– supercritical fluids, water as a solvent for organic reactions, ionic
liquids, fluorous biphasic solvent, PEG, solventless processes, immobilized solvents and
how to compare greenness of solvents.
Energy requirements for reactions – alternative sources of energy: use of microwaves
and ultrasonic energy.
Selection of starting materials; avoidance of unnecessary derivatization – careful use of
blocking/protecting groups.
Use of catalytic reagents (wherever possible) in preference to stoichiometric reagents;
catalysis and green chemistry, comparison of heterogeneous and homogeneous catalysis,
biocatalysis, asymmetric catalysis and photocatalysis.
Prevention of chemical accidents designing greener processes, inherent safer design,
principle of ISD “What you don’t have cannot harm you”, greener alternative to Bhopal
Gas Tragedy (safer route to carcarbaryl) and Flixiborough accident (safer route to
cyclohexanol) subdivision of ISD, minimization, simplification, substitution,
moderation and limitation.
Strengthening/ development of analytical techniques to prevent and minimize the
generation of hazardous substances in chemical processes.
(30 Lectures)
1. Green Synthesis of the following compounds: adipic acid, catechol, disodium iminodiacetate
(alternative to Strecker synthesis)
2. Microwave assisted reactions in water: Hofmann Elimination, methyl benzoate to benzoic
acid, oxidation of toluene and alcohols; microwave assisted reactions in organic solvents Diels-
52
Alder reaction and Decarboxylation reaction
3. Ultrasound assisted reactions: sonochemical Simmons-Smith Reaction (Ultrasonic
alternative to Iodine)
4 Surfactants for carbon dioxide – replacing smog producing and ozone depleting solvents
with CO2 for precision cleaning and dry cleaning of garments.
5 Designing of Environmentally safe marine antifoulant.
6 Rightfit pigment: synthetic azopigments to replace toxic organic and inorganic
pigments.
7 An efficient, green synthesis of a compostable and widely applicable plastic (poly lactic
acid) made from corn.
8 Healthier fats and oil by Green Chemistry: Enzymatic interesterification for production
of no Trans-Fats and Oils
9 Development of Fully Recyclable Carpet: Cradle to Cradle Carpeting
(16 Lectures)
(10 Lectures)
Reference Books:
Ahluwalia, V.K. & Kidwai, M.R. New Trends in Green Chemistry, Anamalaya
Publishers (2005).
Anastas, P.T. & Warner, J.K.: Green Chemistry - Theory and Practical, Oxford
University Press (1998).
Matlack, A.S. Introduction to Green Chemistry, Marcel Dekker (2001).
Cann, M.C. & Connely, M.E. Real-World cases in Green Chemistry, American
Chemical Society, Washington (2000).
Ryan, M.A. & Tinnesand, M. Introduction to Green Chemistry, American Chemical
Society, Washington (2002).
Lancaster, M. Green Chemistry: An Introductory Text RSC Publishing, 2nd Edition,
2010.
-------------------------------------------------------------------------------------------------------
60 Lectures
3. Avoiding waste
Use of molecular model kit to stimulate the reaction to investigate how the atom
economy can illustrate Green Chemistry.
Preparation of propene by two methods can be studied
(I) Triethylamine ion + OH- → propene + trimethylpropene + water
H2SO4/
(II) 1-propanol propene + water
Extraction of D-limonene from orange peel using liquid CO2 prepared form dry ice.
Reference Books:
Anastas, P.T & Warner, J.C. Green Chemistry: Theory and Practice, Oxford University
Press (1998).
Kirchoff, M. & Ryan, M.A. Greener approaches to undergraduate chemistry
experiment. American Chemical Society, Washington DC (2002).
Ryan, M.A. Introduction to Green Chemistry, Tinnesand; (Ed), American Chemical
Society, Washington DC (2002).
Sharma, R.K.; Sidhwani, I.T. & Chaudhari, M.K. I.K. Green Chemistry Experiment: A
monograph International Publishing House Pvt Ltd. New Delhi. Bangalore CISBN 978-
93-81141-55-7 (2013).
Cann, M.C. & Connelly, M. E. Real world cases in Green Chemistry, American
Chemical Society (2008).
Cann, M. C. & Thomas, P. Real world cases in Green Chemistry, American Chemical
Society (2008).
Lancaster, M. Green Chemistry: An Introductory Text RSC Publishing, 2nd Edition,
2010.
Pavia, D.L., Lampman, G.M., Kriz, G.S. & Engel, R.G. Introduction to Organic
Laboratory Techniques: A Microscale and Macro Scale Approach, W.B.Saunders, 1995.
54
----------------------------------------------------------------------------------------------------------------
CHEMISTRY-DSE: BIOINORGANIC & ENVIRONMENTAL CHEMISTRY
(Credits: Theory-04, Practicals-02)
Theory: 60 Lectures
Bio-Inorganic Chemistry
A brief introduction to bio-inorganic chemistry. Role of metal ions present in biological systems
with special reference to Na+, K+ and Mg2+ ions: Na/K pump; Role of Mg2+ ions in energy
production and chlorophyll. Role of Ca2+ in blood clotting, stabilization of protein structures
and structural role (bones).
(12 Lectures)
Pollution by SO2, CO2, CO, NOx, H2S and other foul smelling gases. Methods of estimation of
CO, NOx, SOx and control procedures.
Effects of air pollution on living organisms and vegetation. Greenhouse effect and Global
warming, Ozone depletion by oxides of nitrogen, chlorofluorocarbons and Halogens, removal
of sulphur from coal. Control of particulates.
Water Pollution: Hydrological cycle, water resources, aquatic ecosystems, Sources and nature
of water pollutants, Techniques for measuring water pollution, Impacts of water pollution on
hydrological and ecosystems.
Water purification methods. Effluent treatment plants (primary, secondary and tertiary
treatment). Industrial effluents from the following industries and their treatment: electroplating,
textile, tannery, dairy, petroleum and petrochemicals, agro, fertilizer, etc. Sludge disposal.
Industrial waste management, incineration of waste. Water treatment and purification (reverse
osmosis, electro dialysis, ion exchange). Water quality parameters for waste water, industrial
water and domestic water.
(30 Lectures)
Sources of energy: Coal, petrol and natural gas. Nuclear Fusion / Fission, Solar energy,
Hydrogen, geothermal, Tidal and Hydel, etc.
55
Nuclear Pollution: Disposal of nuclear waste, nuclear disaster and its management.
(10 Lectures)
Biocatalysis
(8 Lectures)
Reference Books:
11. Paper chromatographic separation of Fe3+, A13+ and Cr3+ or paper chromatographic
separation of Ni2+, Co2+, Mn2+ and Zn2+
Reference Books:
E. Stocchi: Industrial Chemistry, Vol-I, Ellis Horwood Ltd. UK.
R.M. Felder, R.W. Rousseau: Elementary Principles of Chemical Processes, Wiley
Publishers, New Delhi.
56
J. A. Kent: Riegel’s Handbook of Industrial Chemistry, CBS Publishers, New Delhi.
S. S. Dara: A Textbook of Engineering Chemistry, S. Chand & Company Ltd. New Delhi.
K. De, Environmental Chemistry: New Age International Pvt. Ltd, New Delhi.
S. M. Khopkar, Environmental Pollution Analysis: Wiley Eastern Ltd, New Delhi.
-------------------------------------------------------------------------------------------------------
Recap of the spectroscopic methods covered in detail in the core chemistry syllabus: Treatment
of analytical data, including error analysis. Classification of analytical methods and the types of
instrumental methods. Consideration of electromagnetic radiation.
(4 Lectures)
Molecular spectroscopy:
Infrared spectroscopy:
Interactions with molecules: absorption and scattering. Means of excitation (light sources),
separation of spectrum (wavelength dispersion, time resolution), detection of the signal (heat,
differential detection), interpretation of spectrum (qualitative, mixtures, resolution), advantages
of Fourier Transform (FTIR). Samples and results expected. Applications: Issues of quality
assurance and quality control, Special problems for portable instrumentation and rapid
detection.
(16 Lectures)
Separation techniques
Mass spectroscopy: Making the gaseous molecule into an ion (electron impact, chemical
ionization), Making liquids and solids into ions (electrospray, electrical discharge, laser
57
desorption, fast atom bombardment), Separation of ions on basis of mass to charge ratio,
Magnetic, Time of flight, Electric quadrupole. Resolution, time and multiple separations,
Detection and interpretation (how this is linked to excitation).
(16 Lectures)
Elemental analysis:
Excitation and getting sample into gas phase (flames, electrical discharges, plasmas),
Wavelength separation and resolution (dependence on technique), Detection of radiation
(simultaneous/scanning, signal noise), Interpretation (errors due to molecular and ionic species,
matrix effects, other interferences).
(8 Lectures)
(4 Lectures)
(4 Lectures)
Reference books:
Skoog, D.A. Holler F.J. & Nieman, T.A. Principles of Instrumental Analysis, Cengage
Learning India Ed.
Willard, H.H., Merritt, L.L., Dean, J. & Settoe, F.A. Instrumental Methods of Analysis, 7th
Ed. Wadsworth Publishing Company Ltd., Belmont, California, USA, 1988.
P.W. Atkins: Physical Chemistry.
G.W. Castellan: Physical Chemistry.
C.N. Banwell: Fundamentals of Molecular Spectroscopy.
Brian Smith: Infrared Spectral Interpretations: A Systematic Approach.
W.J. Moore: Physical Chemistry.
Reference Books:
Skoog, D.A. Holler F.J. & Nieman, T.A. Principles of Instrumental Analysis, Cengage
Learning India Ed.
Willard, H.H., Merritt, L.L., Dean, J. & Settoe, F.A. Instrumental Methods of Analysis, 7th
Ed. Wadsworth Publishing Company Ltd., Belmont, California, USA, 1988.
Reference Books:
Svehla, G. Vogel’s Qualitative Inorganic Analysis, Pearson Education, 2012.
Mendham, J. Vogel’s Quantitative Chemical Analysis, Pearson, 2009.
-----------------------------------------------------------------------------------------------------------
59
CORE COURSE ZOOLOGY I
ANIMAL DIVERSITY
THEORY (CREDITS 4)
60
Unit 13: Amphibia 4
General features and Classification up to orders; Parental care
Note: Classification of Unit 1-9 to be followed from “Barnes, R.D. (1982). Invertebrate
Zoology, V Edition”
61
ANIMAL DIVERSITY
PRACTICAL (CREDITS 2)
An “animal album” containing photographs, cut outs, with appropriate write up about the
above mentioned taxa. Different taxa/ topics may be given to different sets of students for
this purpose.
SUGGESTED READINGS
Ruppert and Barnes, R.D. (2006). Invertebrate Zoology, VIII Edition. Holt Saunders
International Edition.
Barnes, R.S.K., Calow, P., Olive, P.J.W., Golding, D.W. and Spicer, J.I. (2002). The
Invertebrates: A New Synthesis, III Edition, Blackwell Science
Young, J. Z. (2004). The Life of Vertebrates. III Edition. Oxford university press.
Pough H. Vertebrate life, VIII Edition, Pearson International.
Hall B.K. and Hallgrimsson B. (2008). Strickberger’s Evolution. IV Edition. Jones and
Bartlett Publishers Inc.
62
CORE COURSE ZOOLOGY II
THEORY (CREDITS 4)
64
COMPARATIVE ANATOMY AND DEVELOPMENTAL BIOLOGY OF
VERTEBRATES
PRACTICAL (CREDITS 2)
1. Osteology:
a) Disarticulated skeleton of fowl and rabbit
b) Carapace and plastron of turtle /tortoise
c) Mammalian skulls: One herbivorous and one carnivorous animal.
2. Frog - Study of developmental stages - whole mounts and sections through permanent
slides – cleavage stages, blastula, gastrula, neurula, tail bud stage, tadpole external and
internal gill stages.
3. Study of the different types of placenta- histological sections through permanent slides or
photomicrographs.
4. Study of placental development in humans by ultrasound scans.
5. Examination of gametes - frog/rat - sperm and ova through permanent slides or
photomicrographs.
SUGGESTED READINGS
Kardong, K.V. (2005) Vertebrates’ Comparative Anatomy, Function and Evolution. IV
Edition. McGraw-Hill Higher Education.
Kent, G.C. and Carr R.K. (2000). Comparative Anatomy of the Vertebrates. IX Edition.
The McGraw-Hill Companies.
Hilderbrand, M and Gaslow G.E. Analysis of Vertebrate Structure, John Wiley and Sons.
Walter, H.E. and Sayles, L.P; Biology of Vertebrates, Khosla Publishing House.
Gilbert, S. F. (2006). Developmental Biology, VIII Edition, Sinauer Associates, Inc.,
Publishers, Sunderland, Massachusetts, USA.
Balinsky, B.I. (2008). An introduction to Embryology, International Thomson Computer
Press.
Carlson, Bruce M (1996). Patten’s Foundations of Embryology, McGraw Hill, Inc.
65
CORE COURSE ZOOLOGY III
PHYSIOLOGY AND BIOCHEMISTRY
THEORY (CREDITS 4)
Unit 2: Digestion 5
Physiology of digestion in the alimentary canal; Absorption of carbohydrates, proteins, lipids
Unit 3: Respiration 5
Pulmonary ventilation, Respiratory volumes and capacities, Transport of Oxygen and carbon
dioxide in blood
Unit 4: Excretion 5
Structure of nephron, Mechanism of Urine formation, Counter-current Mechanism
66
PHYSIOLOGY AND BIOCHEMISTRY
PRACTICAL (CREDITS 2)
SUGGESTED READINGS
Tortora, G.J. and Derrickson, B.H. (2009). Principles of Anatomy and Physiology, XII
Edition, John Wiley & Sons, Inc.
Widmaier, E.P., Raff, H. and Strang, K.T. (2008) Vander’s Human Physiology, XI
Edition., McGraw Hill
Guyton, A.C. and Hall, J.E. (2011). Textbook of Medical Physiology, XII Edition,
Harcourt Asia Pvt. Ltd/ W.B. Saunders Company
Berg, J. M., Tymoczko, J. L. and Stryer, L. (2006). Biochemistry. VI Edition. W.H
Freeman and Co.
Nelson, D. L., Cox, M. M. and Lehninger, A.L. (2009). Principles of Biochemistry. IV
Edition. W.H. Freeman and Co.
Murray, R.K., Granner, D.K., Mayes, P.A. and Rodwell, V.W. (2009). Harper’s
Illustrated Biochemistry. XXVIII Edition. Lange Medical Books/Mc Graw3Hill.
67
CORE COURSE ZOOLOGY IV
GENETICS AND EVOLUTIONARY BIOLOGY
THEORY (CREDITS 4)
Unit 4: Mutations 7
Chromosomal Mutations: Deletion, Duplication, Inversion, Translocation, Aneuploidy and
Polyploidy; Gene mutations: Induced versus Spontaneous mutations, Back versus Suppressor
mutations,
68
Unit 11: Macro-evolution 5
Macro-evolutionary Principles (example: Darwin’s Finches)
69
GENETICS AND EVOLUTIONARY BIOLOGY
PRACTICAL (CREDITS 2)
1. Study of Mendelian Inheritance and gene interactions (Non Mendelian Inheritance) using
suitable examples. Verify the results using Chi-square test.
2. Study of Linkage, recombination, gene mapping using the data.
3. Study of Human Karyotypes (normal and abnormal).
4. Study of fossil evidences from plaster cast models and pictures
5. Study of homology and analogy from suitable specimens/ pictures
6. Charts:
a) Phylogeny of horse with diagrams/ cut outs of limbs and teeth of horse ancestors
b) Darwin’s Finches with diagrams/ cut outs of beaks of different species
7. Visit to Natural History Museum and submission of report
SUGGESTED READINGS
Gardner, E.J., Simmons, M.J., Snustad, D.P. (2008). Principles of Genetics. VIII
Edition. Wiley India.
Snustad, D.P., Simmons, M.J. (2009). Principles of Genetics. V Edition. John Wiley
and Sons Inc.
Klug, W.S., Cummings, M.R., Spencer, C.A. (2012). Concepts of Genetics. X
Edition. Benjamin Cummings.
Russell, P. J. (2009). Genetics- A Molecular Approach. III Edition. Benjamin
Cummings.
Griffiths, A.J.F., Wessler, S.R., Lewontin, R.C. and Carroll, S.B. Introduction to
Genetic Analysis. IX Edition. W. H. Freeman and Co.
Ridley, M. (2004). Evolution. III Edition. Blackwell Publishing
Barton, N. H., Briggs, D. E. G., Eisen, J. A., Goldstein, D. B. and Patel, N. H. (2007).
Evolution. Cold Spring, Harbour Laboratory Press.
Hall, B. K. and Hallgrimsson, B. (2008). Evolution. IV Edition. Jones and Bartlett
Publishers
Campbell, N. A. and Reece J. B. (2011). Biology. IX Edition, Pearson, Benjamin,
Cummings.
Douglas, J. Futuyma (1997). Evolutionary Biology. Sinauer Associates.
70
DISCIPLINE CENTRIC ELECTIVE COURSES
DSE 1
ANIMAL BIOTECHNOLOGY
THEORY (Credits 4)
Unit 1: Introduction 8
Concept and scope of biotechnology
71
ANIMAL BIOTECHNOLOGY
PRACTICAL (Credits 2)
SUGGESTED READINGS
Brown, T.A. (1998). Molecular Biology Labfax II: Gene Cloning and DNA Analysis. II
Edition, Academic Press, California, USA.
Glick, B.R. and Pasternak, J.J. (2009). Molecular Biotechnology - Principles and
Applications of Recombinant DNA. IV Edition, ASM press, Washington, USA.
Griffiths, A.J.F., J.H. Miller, Suzuki, D.T., Lewontin, R.C. and Gelbart, W.M. (2009).
An Introduction to Genetic Analysis. IX Edition. Freeman and Co., N.Y., USA.
Snustad, D.P. and Simmons, M.J. (2009). Principles of Genetics. V Edition, John Wiley
and Sons Inc.
Watson, J.D., Myers, R.M., Caudy, A. and Witkowski, J.K. (2007). Recombinant DNA-
Genes and Genomes- A Short Course. III Edition, Freeman and Co., N.Y., USA.
Beauchamp, T.I. and Childress, J.F. (2008). Principles of Biomedical Ethics. VI Edition,
Oxford University Press.
72
DSE 2
APPLIED ZOOLOGY
THEORY (CREDITS 4)
73
APPLIED ZOOLOGY
PRACTICAL (CREDITS 2)
SUGGESTED READINGS
Park, K. (2007). Preventive and Social Medicine. XVI Edition. B.B Publishers.
Arora, D. R and Arora, B. (2001). Medical Parasitology. II Edition. CBS Publications
and Distributors.
Kumar and Corton. Pathological Basis of Diseases.
Atwal, A.S. (1986). Agricultural Pests of India and South East Asia, Kalyani
Publishers.
Dennis, H. (2009). Agricultural Entomology. Timber Press (OR).
Hafez, E. S. E. (1962). Reproduction in Farm Animals. Lea & Fabiger Publisher
Dunham R.A. (2004). Aquaculture and Fisheries Biotechnology Genetic Approaches.
CABI publications, U.K.
Pedigo, L.P. (2002). Entomology and Pest Management, Prentice Hall.
74
DCE 3
AQUATIC BIOLOGY
THEORY (Credits 4 )
UNIT 1: Aquatic Biomes
Brief introduction of the aquatic biomes: Freshwater ecosystem (lakes, wetlands,
streams and rivers), estuaries, intertidal zones, oceanic pelagic zone, marine
benthic zone and coral reefs.
UNIT 2: Freshwater Biology
Lakes: Origin and classification, Lake as an Ecosystem, Lake morphometry,
Physico–chemical Characteristics: Light, Temperature, Thermal stratification,
Dissolved Solids, Carbonate, Bicarbonates, Phosphates and Nitrates, Turbidity;
dissolved gases (Oxygen, Carbon dioxide). Nutrient Cycles in Lakes-Nitrogen,
Sulphur and Phosphorous.
Streams: Different stages of stream development, Physico-chemical
environment, Adaptation of hill-stream fishes.
75
PRACTICAL (Credits 2)
1. Determine the area of a lake using graphimetric and gravimetric method.
2. Identify the important macrophytes, phytoplanktons and zooplanktons
present in a lake ecosystem.
3. Determine the amount of Turbidity/transparency, Dissolved Oxygen, Free
Carbon dioxide, Alkalinity (carbonates & bicarbonates) in water collected
from a nearby lake/ water body.
4. Instruments used in limnology (Secchi disc, Van Dorn Bottle, Conductivity
meter, Turbidity meter, PONAR grab sampler) and their significance.
5. A Project Report on a visit to a Sewage treatment plant/Marine bio-
reserve/Fisheries Institutes.
SUGGESTED READINGS
Trivedi and Goyal : Chemical and biological methods for water pollution studies
76
DSE 4
IMMUNOLOGY
THEORY (CREDITS 4)
Unit 3: Antigens 8
Basic properties of antigens, B and T cell epitopes, haptens and adjuvants
Unit 4: Antibodies 8
Structure, classes and function of antibodies, monoclonal antibodies, antigen antibody
interactions as tools for research and diagnosis
Unit 7: Vaccines 4
77
IMMUNOLOGY
PRACTICAL (CREDITS 2)
SUGGESTED READINGS
David, M., Jonathan, B., David, R. B. and Ivan R. (2006). Immunology, VII Edition,
Mosby, Elsevier Publication.
78
DSE 5
REPRODUCTIVE BIOLOGY
THEORY (CREDITS 4)
Gonadal hormones and mechanism of hormone action, steroids, glycoprotein hormones, and
prostaglandins, hypothalamo – hypophyseal – gonadal axis, regulation of gonadotrophin
secretion in male and female; Reproductive System: Development and differentiation of
gonads, genital ducts, external genitalia, mechanism of sex differentiation.
Outline and histological of male reproductive system in rat and human; Testis: Cellular
functions, germ cell, system cell renewal; Spermatogenesis: kinetics and hormonal
regulation; Androgen synthesis and metabolism; Epididymal function and sperm maturation;
Accessory glands functions; Sperm transportation in male tract
Outline and histological of female reproductive system in rat and human; Ovary:
folliculogenesis, ovulation, corpus luteum formation and regression; Steroidogenesis and
secretion of ovarian hormones; Reproductive cycles (rat and human) and their regulation,
changes in the female tract; Ovum transport in the fallopian tubes; Sperm transport in the
female tract, fertilization; Hormonal control of implantation; Hormonal regulation of
gestation, pregnancy diagnosis, foeto – maternal relationship; Mechanism of parturition and
its hormonal regulation; Lactation and its regulation
Infertility in male and female: causes, diagnosis and management; Assisted Reproductive
Technology: sex selection, sperm banks, frozen embryos, in vitro fertilization, ET, EFT,
IUT, ZIFT, GIFT, ICSI, PROST; Modern contraceptive technologies; Demographic
terminology used in family planning
79
REPRODUCTIVE BIOLOGY
PRACTICAL (CREDITS 2)
1. Study of animal house: set up and maintenance of animal house, breeding techniques,
care of normal and experimental animals.
SUGGESTED READINGS
Austin, C.R. and Short, R.V. reproduction in Mammals. Cambridge University Press.
Degroot, L.J. and Jameson, J.L. (eds). Endocrinology. W.B. Saunders and Company.
80
GE 6
INSECT, VECTORS AND DISEASES
THEORY (Credits 4)
Study of house fly as important mechanical vector, Myiasis, Control of house fly
81
82
INSECT VECTORS AND DISEASES
PRACTICAL (CREDITS 2)
1. Study of different kinds of mouth parts of insects
2. Study of following insect vectors through permanent slides/ photographs:
Aedes, Culex, Anopheles, Pediculus humanus capitis, Pediculus humanus
corporis, Phithirus pubis, Xenopsylla cheopis, Cimex lectularius,
Phlebotomus argentipes, Musca domestica, through permanent slides/
photographs
3. Study of different diseases transmitted by above insect vectors
Submission of a project report on any one of the insect vectors and disease transmitted
SUGGESTED READINGS
Imms, A.D. (1977). A General Text Book of Entomology. Chapman & Hall, UK
Chapman, R.F. (1998). The Insects: Structure and Function. IV Edition, Cambridge
University Press, UK
Pedigo L.P. (2002). Entomology and Pest Management. Prentice Hall Publication
83
Skill Enhancement Courses
Botany
Biofertilizers
(Credits 2)
Lectures: 30
Unit 1:General account about the microbes used as biofertilizer – Rhizobium – isolation,
identification, mass multiplication, carrier based inoculants, Actinorrhizal symbiosis.
(4 Lectures)
Unit 2: Azospirillum: isolation and mass multiplication – carrier based inoculant, associative
effect of different microorganisms. Azotobacter: classification, characteristics – crop
response to Azotobacter inoculum, maintenance and mass multiplication. (8 Lectures)
Unit 3:Cyanobacteria (blue green algae), Azolla and Anabaena azollae association, nitrogen
fixation, factors affecting growth, blue green algae and Azolla in rice cultivation.
(4 Lectures)
(8 Lectures)
Unit 5:Organic farming – Green manuring and organic fertilizers, Recycling of bio-
degradable municipal, agricultural and Industrial wastes – biocompost making methods,
types and method of vermicomposting – field Application. (6 Lectures)
Suggested Readings
1. Dubey, R.C., 2005 A Text book of Biotechnology S.Chand & Co, New Delhi.
2. Kumaresan, V. 2005, Biotechnology, Saras Publications, New Delhi.
3. John Jothi Prakash, E. 2004. Outlines of Plant Biotechnology. Emkay
Publication, New
Delhi.
4. Sathe, T.V. 2004 Vermiculture and Organic Farming. Daya publishers.
5. Subha Rao, N.S. 2000, Soil Microbiology, Oxford & IBH Publishers, New
Delhi.
6. Vayas,S.C, Vayas, S. and Modi, H.A. 1998 Bio-fertilizers and organic
Farming Akta
Prakashan, Nadiad
84
Skill Enhancement Course
Botany
Herbal Technology
(Credits 2)
Lectures: 30
Unit 1: Herbal medicines: history and scope - definition of medical terms - role of medicinal
plants in Siddha systems of medicine; cultivation - harvesting - processing - storage -
marketing and utilization of medicinal plants. (6 Lectures)
Unit 3: Phytochemistry - active principles and methods of their testing - identification and
utilization of the medicinal herbs; Catharanthus roseus (cardiotonic), Withania somnifera
(drugs acting on nervous system), Clerodendron phlomoides (anti-rheumatic) and Centella
asiatica (memory booster). (6 Lectures)
Unit 5: Medicinal plant banks micro propagation of important species (Withania somnifera,
neem and tulsi- Herbal foods-future of pharmacognosy) (4 Lectures)
Suggested Readings
2. The indigenous drugs of India, Kanny, Lall, Dey and Raj Bahadur, 1984.
International Book
Distributors.
3. Herbal plants and Drugs Agnes Arber, 1999. Mangal Deep Publications.
4. Ayurvedic drugs and their plant source. V.V. Sivarajan and Balachandran Indra 1994.
Oxford IBH
publishing Co.
5. Ayurveda and Aromatherapy. Miller, Light and Miller, Bryan, 1998. Banarsidass, Delhi.
85
7. Pharmacognosy, Dr.C.K.Kokate et al. 1999. Nirali Prakashan.
(Credits 2)
Lectures: 30
Unit 1: Nursery: definition, objectives and scope and building up of infrastructure for
nursery, planning and seasonal activities - Planting - direct seeding and transplants. (4
Lectures)
Unit 2: Seed: Structure and types - Seed dormancy; causes and methods of breaking
dormancy - Seed storage: Seed banks, factors affecting seed viability, genetic erosion - Seed
production technology - seed testing and certification. (6 Lectures)
Suggested Readings
1. Bose T.K. & Mukherjee, D., 1972, Gardening in India, Oxford & IBH Publishing
Co., New Delhi.
2. Sandhu, M.K., 1989, Plant Propagation, Wile Eastern Ltd., Bangalore, Madras.
3. Kumar, N., 1997, Introduction to Horticulture, Rajalakshmi Publications, Nagercoil.
4. Edmond Musser & Andres, Fundamentals of Horticulture, McGraw Hill Book Co.,
New Delhi.
5. Agrawal, P.K. 1993, Hand Book of Seed Technology, Dept. of Agriculture and
86
Cooperation, National
Seed Corporation Ltd., New Delhi.
6. Janick Jules. 1979. Horticultural Science. (3rd Ed.), W.H. Freeman and Co., San
Francisco, USA.
Floriculture
(Credits 2)
Lectures: 30
Unit 1: Introduction: History of gardening; Importance and scope of floriculture and
landscape gardening. (2 Lectures)
Unit 2: Nursery Management and Routine Garden Operations: Sexual and vegetative
methods of propagation; Soil sterilization; Seed sowing; Pricking; Planting and
transplanting; Shading; Stopping or pinching; Defoliation; Wintering; Mulching; Topiary;
Role of plant growth regulators.
(8 Lectures)
Unit 3: Ornamental Plants: Flowering annuals; Herbaceous perennials; Divine vines; Shade
and ornamental trees; Ornamental bulbous and foliage plants; Cacti and succulents; Palms
and Cycads; Ferns and Selaginellas; Cultivation of plants in pots; Indoor gardening; Bonsai.
(4 Lectures)
Unit 4: Principles of Garden Designs: English, Italian, French, Persian, Mughal and
Japanese gardens; Features of a garden (Garden wall, Fencing, Steps, Hedge, Edging, Lawn,
Flower beds, Shrubbery, Borders, Water garden. Some Famous gardens of India. (4
Lectures)
87
Suggested Readings
88
Skill Enhancement Course
Botany
Medicinal Botany
(Credits 2)
Lectures: 30
Unit 1: History, Scope and Importance of Medicinal Plants. Indigenous Medicinal Sciences;
Definition and Scope-Ayurveda: History, origin, panchamahabhutas, saptadhatu and tridosha
concepts, Rasayana, plants used in ayurvedic treatments, Siddha: Origin of Siddha medicinal
systems, Basis of Siddha system, plants used in Siddha medicine. Unani: History, concept:
Umoor-e- tabiya, tumors treatments/ therapy, polyherbal formulations. (10 Lectures)
Unit 2: Conservation of endangered and endemic medicinal plants. Definition: endemic and
endangered medicinal plants, Red list criteria; In situ conservation: Biosphere reserves,
sacred groves, National Parks; Ex situ conservation: Botanic Gardens, Ethnomedicinal plant
Gardens. Propagation of Medicinal Plants: Objectives of the nursery, its classification,
important components of a nursery, sowing, pricking, use of green house for nursery
production, propagation through cuttings, layering, grafting and budding. (10 Lectures)
Suggested Readings
2. Purohit and Vyas, 2008. Medicinal Plant Cultivation: A Scientific Approach, 2nd edn.
Agrobios, India.
89
Skill Enhancement Course
Plant Diversity and Human Welfare
(Credits 2)
Lectures: 30
Unit 1: Plant diversity and its scope- Genetic diversity, Species diversity, Plant diversity at
theecosystem level, Agrobiodiversity and cultivated plant taxa, wild taxa. Values and uses of
Biodiversity: Ethical and aesthetic values, Precautionary principle, Methodologies for
valuation, Uses of plants, Uses of microbes. (8 Lectures)
Unit 2:Loss of Biodiversity: Loss of genetic diversity, Loss of species diversity, Loss of
ecosystem diversity, Loss of agrobiodiversity, Projected scenario for biodiversity loss,
Management of Plant Biodiversity: Organizations associated with biodiversity
management-Methodology for execution-IUCN, UNEP, UNESCO, WWF, NBPGR;
Biodiversity legislation and conservations, Biodiversity information management and
communication. (8 Lectures)
Suggested Readings
90
Skill Enhancement Course
Botany
Ethnobotany
(Credits 2)
Lectures: 30
Unit 1: Ethnobotany
Introduction, concept, scope and objectives; Ethnobotany as an interdisciplinary science.
The relevance of ethnobotany in the present context; Major and minor ethnic groups or
Tribals of India, and their life styles. Plants used by the tribals: a) Food plants b) intoxicants
and beverages c) Resins and oils and miscellaneous uses. (6 Lectures)
Suggested Readings
91
Pradesh, India. Botanical Survey of India. Howrah.
8) Rajiv K. Sinha – Ethnobotany The
Renaissance of Traditional Herbal Medicine – INA –SHREE Publishers, Jaipur-1996
9)
92
Skill Enhancement Course
Botany
Mushroom Culture Technology
(Credits 2)
Lectures: 30
Unit 3: Storage and nutrition : Short-term storage (Refrigeration - upto 24 hours) Long term
Storage (canning, pickels, papads), drying, storage in saltsolutions. Nutrition - Proteins -
amino acids, mineral elements nutrition - Carbohydrates, Crude fibre content - Vitamins.
(8 Lectures)
Unit 4: Food Preparation
: Types of foods prepared from mushroom. Research Centres -
National level and Regional level.
Cost benefit ratio - Marketing in India and abroad, Export
Value. (5 Lectures)
Suggested Readings
93
Skill Enhancement Course
Botany
Intellectual Property Rights
(Credits 2)
Lectures: 30
Unit 1: Introduction to intellectual property right (IPR) (2 lectures)
Concept and kinds. Economic importance. IPR in India and world: Genesis and scope, some
important examples.IPR and WTO (TRIPS, WIPO).
Objectives, Rights, Patent Act 1970 and its amendments. Procedure of obtaining patents,
Working of patents. Infringement.
94
protection in India. Rights of farmers, Breeders and Researchers.National gene bank, Benefit
sharing.Protection of Plant Varieties and Farmers’ Rights Act, 2001.
Computer Software and Intellectual Property, Database and Data Protection, Protection of
Semi-conductor chips, Domain Name Protection
Suggested Readings
1. N.S. Gopalakrishnan & T.G. Agitha, (2009) Principles of Intellectual Property Eastern
Book Company, Lucknow.
2. Kerly’s Law of Trade Marks and Trade Names (14th Edition) Thomson, Sweet &
Maxweel.
3. Ajit Parulekar and Sarita D’ Souza, (2006) Indian Patents Law – Legal & Business
Implications; Macmillan India Ltd.
4. B.L.Wadehra (2000) Law Relating to Patents, Trade Marks, Copyright, Designs &
Geographical Indications; Universal law Publishing Pvt. Ltd., India.
5. P. Narayanan (2010) Law of Copyright and Industrial Designs; Eastern law House,
Delhi.
95
Skill Enhancement Course (any four) (Credit: 02 each)- SEC1 to SEC4
Chemistry
IT SKILLS FOR CHEMISTS
(Credits: 02)
30 Lectures
Mathematics
Algebraic operations on real scalar variables (e.g. manipulation of van der Waals equation in
different forms).Roots of quadratic equations analytically and iteratively (e.g. pH of a weak
acid). Numerical methods of finding roots (Newton-Raphson, binary –bisection, e.g. pH of a
weak acid not ignoring the ionization of water, volume of a van der Waals gas, equilibrium
constant expressions).
Differential calculus: The tangent line and the derivative of a function, numerical
differentiation (e.g., change in pressure for small change in volume of a van der Waals gas,
potentiometric titrations).
Numerical integration (Trapezoidal and Simpson’s rule, e.g. entropy/enthalpy change from
heat capacity data).
Computer programming:
Constants, variables, bits, bytes, binary and ASCII formats, arithmetic expressions, hierarchy
of operations, inbuilt functions. Elements of the BASIC language. BASIC keywords and
commands. Logical and relative operators. Strings and graphics. Compiled versus interpreted
languages. Debugging. Simple programs using these concepts. Matrix addition and
multiplication. Statistical analysis.
BASIC programs for curve fitting, numerical differentiation and integration (Trapezoidal
rule, Simpson’s rule), finding roots (quadratic formula, iterative, Newton-Raphson method).
HANDS ON
96
Introductory writing activities: Introduction to word processor and structure drawing
(ChemSketch) software. Incorporating chemical structures, chemical equations, expressions
from chemistry (e.g. Maxwell-Boltzmann distribution law, Bragg’s law, van der Waals
equation, etc.) into word processing documents.
Handling numeric data: Spreadsheet software (Excel), creating a spreadsheet, entering and
formatting information, basic functions and formulae, creating charts, tables and graphs.
Incorporating tables and graphs into word processing documents. Simple calculations,
plotting graphs using a spreadsheet (Planck’s distribution law, radial distribution curves for
hydrogenic orbitals, gas kinetic theory- Maxwell-Boltzmann distribution curves as function
of temperature and molecular weight), spectral data, pressure-volume curves of van der
Waals gas (van der Waals isotherms), data from phase equilibria studies. Graphical solution
of equations.
Numeric modelling: Simulation of pH metric titration curves. Excel functions LINEST and
Least Squares. Numerical curve fitting, linear regression (rate constants from concentration-
time data, molar extinction coefficients from absorbance data), numerical differentiation
(e.g. handling data from potentiometric and pH metric titrations, pKa of weak acid),
integration (e.g. entropy/enthalpy change from heat capacity data).
Statistical analysis: Gaussian distribution and Errors in measurements and their effect on
data sets. Descriptive statistics using Excel. Statistical significance testing: The t test. The F
test.
Reference Books:
McQuarrie, D. A. Mathematics for Physical Chemistry University Science Books
(2008).
rd
Mortimer, R. Mathematics for Physical Chemistry. 3 Ed. Elsevier (2005).
Steiner, E. The Chemical Maths Book Oxford University Press (1996).
nd
Yates, P. Chemical calculations. 2 Ed. CRC Press (2007).
Harris, D. C. Quantitative Chemical Analysis. 6th Ed., Freeman (2007) Chapters 3-5.
Levie, R. de, How to use Excel in analytical chemistry and in general scientific data
analysis, Cambridge Univ. Press (2001) 487 pages.
Noggle, J. H. Physical chemistry on a Microcomputer. Little Brown & Co. (1985).
Venit, S.M. Programming in BASIC: Problem solving with structure and style. Jaico
Publishing House: Delhi (1996).
97
BASIC ANALYTICAL CHEMISTRY
(Credits: 02)
30 Lectures
Analysis of water: Definition of pure water, sources responsible for contaminating water,
water sampling methods, water purification methods.
Analysis of food products: Nutritional value of foods, idea about food processing and food
preservations and adulteration.
a. Identification of adulterants in some common food items like coffee powder, asafoetida,
chilli powder, turmeric powder, coriander powder and pulses, etc.
b. Analysis of preservatives and colouring matter.
a. Analysis of deodorants and antiperspirants, Al, Zn, boric acid, chloride, sulphate.
b. Determination of constituents of talcum powder: Magnesium oxide, Calcium oxide, Zinc
oxide and Calcium carbonate by complexometric titration.
98
Suggested Instrumental demonstrations:
Reference Books:
Willard, H.H., Merritt, L.L., Dean, J. & Settoe, F.A. Instrumental Methods of
Analysis. 7th Ed. Wadsworth Publishing Co. Ltd., Belmont, California, USA, 1988.
Skoog, D.A. Holler F.J. & Nieman, T.A. Principles of Instrumental Analysis,
Cengage Learning India Ed.
Skoog, D.A.; West, D.M. & Holler, F.J. Fundamentals of Analytical Chemistry 6th
Ed., Saunders College Publishing, Fort Worth (1992).
Harris, D. C. Quantitative Chemical Analysis, W. H. Freeman.
Dean, J. A. Analytical Chemistry Notebook, McGraw Hill.
Day, R. A. & Underwood, A. L. Quantitative Analysis, Prentice Hall of India.
Freifelder, D. Physical Biochemistry 2nd Ed., W.H. Freeman and Co., N.Y. USA
(1982).
Cooper, T.G. The Tools of Biochemistry, John Wiley and Sons, N.Y. USA. 16
(1977).
Vogel, A. I. Vogel’s Qualitative Inorganic Analysis 7th Ed., Prentice Hall.
Vogel, A. I. Vogel’s Quantitative Chemical Analysis 6th Ed., Prentice Hall.
Robinson, J.W. Undergraduate Instrumental Analysis 5th Ed., Marcel Dekker, Inc., New
York (1995).
99
CHEMICAL TECHNOLOGY & SOCIETY
(Credits: 02)
Theory: 30 Lectures
Chemical Technology
Society
Exploration of societal and technological issues from a chemical perspective. Chemical and
scientific literacy as a means to better understand topics like air and water (and the trace
materials found in them that are referred to as pollutants); energy from natural sources (i.e.
solar and renewable forms), from fossil fuels and from nuclear fission; materials like plastics
and polymers and their natural analogues, proteins and nucleic acids, and molecular
reactivity and interconversions from simple examples like combustion to complex instances
like genetic engineering and the manufacture of drugs.
Reference Book:
John W. Hill, Terry W. McCreary & Doris K. Kolb, Chemistry for changing times 13th Ed.
100
CHEMOINFORMATICS
(Credits: 02)
Theory: 30 Lectures
Searching chemical structures: Full structure search, sub-structure search, basic ideas,
similarity search, three dimensional search methods, basics of computation of physical and
chemical data and structure descriptors, data visualization.
Hands-on Exercises
Reference Books:
Andrew R. Leach & Valerie, J. Gillet (2007) An introduction to Chemoinformatics.
Springer: The Netherlands.
Gasteiger, J. & Engel, T. (2003) Chemoinformatics: A text-book. Wiley-VCH.
Gupta, S. P. (2011) QSAR & Molecular Modeling. Anamaya Pub.: New Delhi.
101
BUSINESS SKILLS FOR CHEMISTS
(Credits: 02)
Theory: 30 Lectures
Business Basics
Key business concepts: Business plans, market need, project management and routes to
market.
Chemistry in Industry
Current challenges and opportunities for the chemistry-using industries, role of chemistry in
India and global economies.
Making money
Intellectual property
Reference
www.rsc.org
102
ANALYTICAL CLINICAL BIOCHEMISTRY
(Credits: 02)
THEORY: 30 Lectures
Basic understanding of the structures, properties and functions of carbohydrates, lipids
and proteins:
Lipoproteins.
Structure of DNA (Watson-Crick model) and RNA, Genetic Code, Biological roles of DNA
and RNA: Replication, Transcription and Translation, Introduction to Gene therapy.
Practicals
103
2. Lipids – qualitative.
3. Determination of the iodine number of oil.
4. Determination of the saponification number of oil.
5. Determination of cholesterol using Liebermann- Burchard reaction.
6. Proteins – qualitative.
7. Isolation of protein.
8. Determination of protein by the Biuret reaction.
9. Determination of nucleic acids
Reference Books:
T.G. Cooper: Tool of Biochemistry.
Keith Wilson and John Walker: Practical Biochemistry.
Alan H Gowenlock: Varley’s Practical Clinical Biochemistry.
Thomas M. Devlin: Textbook of Biochemistry.
Berg, J.M., Tymoczko, J.L. & Stryer, L. Biochemistry, W.H. Freeman, 2002.
Talwar, G.P. & Srivastava, M. Textbook of Biochemistry and Human Biology, 3rd Ed.
PHI Learning.
Nelson, D. L. & Cox, M. M. Lehninger’s Principles of Biochemistry 7th Ed., W. H.
Freeman.
Mikes, O. Laboratory Hand Book of Chromatographic & Allied Methods, Elles
Harwood Series on Analytical Chemistry, John Wiley & Sons, 1979.
104
GREEN METHODS IN CHEMISTRY
(Credits: 02)
Theory: 30 Lectures
Surfactants for carbon dioxide – Replacing smog producing and ozone depleting
solvents with CO2 for precision cleaning and dry cleaning of garments.
Designing of environmentally safe marine antifoulant.
Rightfit pigment: Synthetic azo pigments to replace toxic organic and inorganic
pigments.
An efficient, green synthesis of a compostable and widely applicable plastic (poly
lactic acid) made from corn.
Practicals
Reference Books:
Anastas, P.T. & Warner, J.K. Green Chemistry- Theory and Practical, Oxford
University Press (1998).
Matlack, A.S. Introduction to Green Chemistry, Marcel Dekker (2001).
Cann, M.C. & Connely, M.E. Real-World cases in Green Chemistry, American
Chemical Society, Washington (2000).
Ryan, M.A. & Tinnesand, M. Introduction to Green Chemistry, American
Chemical Society, Washington (2002).
Sharma, R.K.; Sidhwani, I.T. & Chaudhari, M.K. Green Chemistry Experiments:
A monograph I.K. International Publishing House Pvt Ltd. New Delhi,
Bangalore.
Lancaster, M. Green Chemistry: An introductory text RSC publishing, 2nd
Edition.
Sidhwani, I.T., Saini, G., Chowdhury, S., Garg, D., Malovika, Garg, N. Wealth
from waste: A green method to produce biodiesel from waste cooking oil and
generation of useful products from waste further generated “A Social Awareness
105
Project”, Delhi University Journal of Undergraduate Research and Innovation,
1(1): 2015.
-------------------------------------------------------------------------------------------------------
PHARMACEUTICAL CHEMISTRY
(Credits: 02)
Theory: 30 Lectures
Practicals
1. Preparation of Aspirin and its analysis.
2. Preparation of magnesium bisilicate (Antacid).
Reference Books:
G.L. Patrick: Introduction to Medicinal Chemistry, Oxford University Press, UK.
Hakishan, V.K. Kapoor: Medicinal and Pharmaceutical Chemistry, Vallabh
Prakashan, Pitampura, New Delhi.
William O. Foye, Thomas L., Lemke , David A. William: Principles of Medicinal
Chemistry, B.I. Waverly Pvt. Ltd. New Delhi.
-------------------------------------------------------------------------------------
A general study including preparation and uses of the following: Hair dye, hair spray,
shampoo, suntan lotions, face powder, lipsticks, talcum powder, nail enamel, creams (cold,
vanishing and shaving creams), antiperspirants and artificial flavours. Essential oils and their
importance in cosmetic industries with reference to Eugenol, Geraniol, sandalwood oil,
eucalyptus, rose oil, 2-phenyl ethyl alcohol, Jasmone, Civetone, Muscone.
Practicals
1. Preparation of talcum powder.
2. Preparation of shampoo.
3. Preparation of enamels.
4. Preparation of hair remover.
106
5. Preparation of face cream.
6. Preparation of nail polish and nail polish remover.
Reference Books:
E. Stocchi: Industrial Chemistry, Vol -I, Ellis Horwood Ltd. UK.
P.C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.
Sharma, B.K. & Gaur, H. Industrial Chemistry, Goel Publishing House, Meerut
(1996).
-----------------------------------------------------------------------------------------
PESTICIDE CHEMISTRY
(Credits: 02)
30 Lectures
General introduction to pesticides (natural and synthetic), benefits and adverse effects,
changing concepts of pesticides, structure activity relationship, synthesis and technical
manufacture and uses of representative pesticides in the following classes: Organochlorines
(DDT, Gammexene,); Organophosphates (Malathion, Parathion ); Carbamates (Carbofuran
and carbaryl); Quinones ( Chloranil), Anilides (Alachlor and Butachlor).
Practicals
1 To calculate acidity/alkalinity in given sample of pesticide formulations as per
BIS specifications.
2 Preparation of simple organophosphates, phosphonates and thiophosphates
Reference Book:
Cremlyn, R. Pesticides. Preparation and Modes of Action, John Wiley & Sons, New
York, 1978.
-----------------------------------------------------------------------------------------
FUEL CHEMISTRY
(Credits: 02)
30 Lectures
Review of energy sources (renewable and non-renewable). Classification of fuels and their
calorific value.
Coal: Uses of coal (fuel and nonfuel) in various industries, its composition, carbonization of
coal.Coal gas, producer gas and water gas—composition and uses. Fractionation of coal tar,
uses of coal tar bases chemicals, requisites of a good metallurgical coke, Coal gasification
(Hydro gasification and Catalytic gasification), Coal liquefaction and Solvent Refining.
Fractional Distillation (Principle and process), Cracking (Thermal and catalytic cracking),
Reforming Petroleum and non-petroleum fuels (LPG, CNG, LNG, bio-gas, fuels derived
107
from biomass), fuel from waste, synthetic fuels (gaseous and liquids), clean fuels.
Petrochemicals: Vinyl acetate, Propylene oxide, Isoprene, Butadiene, Toluene and its
derivatives Xylene.
Properties of lubricants (viscosity index, cloud point, pore point) and their determination.
Reference Books:
Stocchi, E. Industrial Chemistry, Vol-I, Ellis Horwood Ltd. UK (1990).
Jain, P.C. & Jain, M. Engineering Chemistry Dhanpat Rai & Sons, Delhi.
Sharma, B.K. & Gaur, H. Industrial Chemistry, Goel Publishing House, Meerut
(1996).
-------------------------------------------------------------------------------------------------------
Zoology
Apiculture
(CREDITS 2)
108
Bee Keeping Industry – Recent Efforts, Modern Methods in employing artificial
Beehives for cross pollination in horticultural gardens
SUGGESTED READINGS
109
Skill Enhancement Course
Zoology
110
Skill Enhancement Course
Zoology
MEDICAL DIAGNOSTICS
THEORY (Credits 2)
Unit 6: Tumours 3
Types (Benign/Malignant), Detection and metastasis; Medical imaging: X-Ray of Bone
fracture, PET, MRI and CT Scan (using photographs).
SUGGESTED READINGS
Park, K. (2007), Preventive and Social Medicine, B.B. Publishers
Godkar P.B. and Godkar D.P. Textbook of Medical Laboratory Technology, II
Edition, Bhalani Publishing House
Cheesbrough M., A Laboratory Manual for Rural Tropical Hospitals, A Basis for
Training Courses
Guyton A.C. and Hall J.E. Textbook of Medical Physiology, Saunders
Robbins and Cortan, Pathologic Basis of Disease, VIIIEdition, Saunders
Prakash, G. (2012), Lab Manual on Blood Analysis and Medical Diagnostics, S.
Chand and Co. Ltd.
111
Skill Enhancement Course
Zoology
RESEARCH METHODOLOGY
CREDITS 2
Need for research design: Features of good design, Important concepts related to
good design- Observation and Facts, Prediction and Explanation, Development
of Models. Developing a research plan: Problem identification, Experimentation,
Determining experimental and sample designs
SUGGESTED READINGS
Anthony, M, Graziano, A.M. and Raulin, M.L. 2009. Research Methods: A Process
of Inquiry, Allyn and Bacon.
Walliman, N. 2011.Research Methods- The Basics. Taylor and Francis, London,
New York.
Wadhera, B.L.: Law Relating to Patents, Trade Marks, Copyright Designs and
Geographical Indications, 2002, Universal Law publishing
C.R.Kothari: Research Methodology, New Age International, 2009
Coley, S.M. and Scheinberg, C.A. 1990, “Proposal writing”. Stage Publications
112
Skill Enhancement Course
Zoology
SERICULTURE
(CREDITS 2)
SUGGESTED READINGS
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A Guide for Bivoltine Sericulture; K. Sengupta, Director, CSR & TI, Mysore 1989.
Improved Method of Rearing Young age silkworm; S. Krishnaswamy, reprinted
CSB, Bangalore, 1986.
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