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Tugas 2 Kosmetik PDF
Tugas 2 Kosmetik PDF
Tugas 2 Kosmetik PDF
Teknologi Solida
Nizar Rahmatun Najih, S.Farm., Apt.
Sabtu, 14-09-2019
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KOSMETIK
SELAMAT MENGERJAKAN
Research Article Sathish et al.,
eISSN 2249-5797
Introduction:
Lipstick is generally accepted as an essential and
The practice of applying colour to cheeks and lips
leading makeup device available in verity of luster
is very old. In ancient time, natural materials used
and texture. It is composed mainly of a oil-wax
to be applied. Greeks used to colour their lips with
base, stift enough to form a stick with a staining
a root called polderos. Today, lipstick is one of
dye dissolved or dispersed in oil, and pigment
the most widely used cosmetic by women.
suspended there in, suitably performed and
Lipstick is used to make appearance of lips by
flavored, molded and enclosed in a case. Lipstick
imparting colour. Narrow lips can be made to
impart attractive colour, glossy appearances to
appear wider by applying lipsticks above the
lips, accentuating good point and distinguishing
upper lip line.(1)
the defects. It also prevents cracking and chafing
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Sathish et al.,
of lips which lead to bacterial infection. It also regeneration, and helps in healing; antibacterial
provides emollient action on lips.(2) activity of honey is largely due to the presence of
Lipstick formulations are most widely used to hydrogen peroxide (9). Cow ghee has a great
enhance the beauty of lips and to add glamour historical background for skin care and
touch to the make up(3). Any preparations used in nourishment and is highly effective for all sorts of
beauty treatments for lip make-up also known as skin rashes. It also acts as a moisturizer (10).
sticks or more commonly known in beauty Materials and methods
treatments by the name of lipsticks. When these Materials:
preparations contain active ingredients, they are Salicylic acid and carminosine colour lake
also known as medicated lipsticks.(4)
obtained as gift sample from the Dr. Reddy’s
Medicated lipsticks-Glamorous medication
option: Laboratories. Honey (A grade) and cow ghee was
Medicated cosmetics can be used to cure skin purchased from the market. Waxes and other
problems by achieving esthetic sense. Lipsticks excipients of AR grade were used from the Prasad
are cosmetic formulations for the modification or Institute of Pharmaceutical sciences.
accentuation of lip colour and are prepared by Methodology
moulding a dispersion of colours in a waxy base, Preparation of lipstick base: (7),(11),(12)
in the form of stick/crayon (5). The consumption of Colour lake was triturated and dissolved in cow
lipsticks in makeup preparation field exceeds that ghee at 500C, weighed amount of bees wax and
of any other product. Rather than decreasing in carnauba wax were melted at 800C. Colour phase
use, they possess increasing popularity. No was added to molten wax phase and cooled at
substitute has been found to replace them (6). 600C, followed by addition of honey. The mixture
Lipsticks provide a convenient means of either was stirred vigorously till a smooth emulsion was
freshening a makeup by coloring or protection of formed.
lips from the effects of cold, dry weather, UV Table 1: Preparation of lipstick base:
light, and wind (7).
Ingredients Quantity (%)
Suitable drug candidates for medicated lipsticks
are local acting agents including soothing, anti- Beeswax 10
irritant agent, skin protectant, keratolytic agent, Carnauba wax 8
steroids, antibiotics, and anti-inflammatory Lanolin 5
agents. Salicylic acid was selected as a drug of Cetyl alcohol 5
choice because of their anti-irritating, keratolytic, Castor oil 65
abrasive, astringent, healing, moisturizing Isopropyl myristate 5
properties, soothing and non-toxic agent and used
in the treatment of skin ulcers, wound, scalds,
burns, sunburns, carbuncles, acne skin eruptions,
fissures and abrasions ,impetigo ,eczema and
psoriasis. It is effective at quite low concentration,
0.1-2%w/w.(8)
Aim and objective of the present study
was to formulate medicated lipsticks with cow
ghee and honey as natural excipients that replaced
conventional synthetic vehicles of lipsticks. The
castor oil was replaced by cow ghee and
formulations were subjected to the different Fig1: water in oil emulsion Honey (colorless
evaluation. Honey helps to promote tissue droplets) as water phase wax and ghee (colored
droplets) as oily phase
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Sathish et al.,
Preparation of medicated (Salicylic acid) (SLS), slowly this mixture was added with
lipstick: continuous stirring at 500 rpm using overhead
Accurately weighed amount of Salicylic acid was stirrer (universal motor). The mixture was poured
dissolved in 0.5ml water by using 0.05% in clean and lubricated moulds & chilled to
surfactant sodium lauryl sulphate (SLS), slowly achieve contraction of the waxes to facilitate easy
this mixture was added with continuous stirring at removal of the stick.
500 rpm using overhead stirrer (universal motor). Table 4: Preparation of medicated (Salicylic
The mixture was poured in clean and lubricated acid & Zinc oxide) lipstick:
moulds & chilled to achieve contraction of the Ingredients Quantity (%)
waxes to facilitate easy removal of the stick. Bees wax 10
Table 2: Preparation of medicated (Salicylic Carnauba wax 8
acid) lipstick: Ghee 75
Ingredients Quantity (%) Honey 5
Bees wax 10 Zinc oxide 0.5
Carnauba wax 8 Salicylic acid 0.5
Ghee 75 Colour 2
Honey 5 Sodium lauryl sulphate 0.05
Salicylic acid 0.5 Propyl paraben 0.05
Colour 2 Evaluation parameters
Sodium lauryl sulphate 0.05 1) Melting point:(7),(11)
Propyl paraben 0.05 Lipstick sample of 50mg was taken. This was
Preparation of medicated (Zinc oxide) lipstick: melted and filled into a glass capillary tube open
Accurately weighed amount of Zinc oxide was on both the ends. This capillary tube was cooled
dissolved in 0.5ml water by using 0.05% in ice for about 2 hours and fastens it to a
surfactant sodium lauryl sulphate (SLS), slowly thermometer. This assembly was dipped into a
this mixture was added with continuous stirring at beaker full of water and was heated with
500 rpm using overhead stirrer (universal motor). continuous stirring. The temperature at which the
The mixture was poured in clean and lubricated material moves along threw capillary tube was
moulds & chilled to achieve contraction of the considered its melting point.
waxes to facilitate easy removal of the stick. 2) Softening point(ring and ball method)(7)
Table 3: Preparation of medicated (Zinc oxide) The lipstick sample was inserted into an
lipstick:
aluminum ring. Extra mass above and below the
Ingredients Quantity (%)
Bees wax 10 orifice was removed using a sharp blade to get a
Carnauba wax 8 lipstick tablet into the ring. This was placed in a
Ghee 75 refrigerator (60C) for 10mins. After removing it
Honey 5 from the refrigerator, the ring was fastened onto a
Zinc oxide 0.5 stand and a steel ball was delicately placed on the
Colour 2 lipstick tablet. This assembly was dipped into a
Sodium lauryl sulphate 0.05 beaker full of water. Temperature was monitored
Propyl paraben 0.05 using a thermometer. Softening point was the
Preparation of medicated (Salicylic acid &
temperature at which both the lipstick mass and
Zinc oxide) lipstick:
Accurately weighed amount of Zinc oxide & the steel ball were loosened and falls to the
Salicylic acid was dissolved in 0.5ml water by bottom of the beaker.
using 0.05% surfactant sodium lauryl sulphate
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Sathish et al.,
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Sathish et al.,
ingredients in treatment of lips and consumer 9. Krell R. Value added products from beekeeping.
acceptance of formulation. The prepared lipsticks Agricultural service bulletin 124. Food Agr
were show excellent properties like shining, Organ United Nation 1996; 55:117-314.
spreading and smoothness of lips. The medicated 10. Medicated properties and uses of ghee. Arya
lipsticks of salicylic acid have not exhibited Bhishak Sastu Sahita. Gujarat: Yardhak
systemic drug release through the bovine lip Karayalaya; 1961. p. 672-3.
membrane for 6 h, thus showing maximum local 11. Balsam S. Cosmetics, science and technology.
effect on lips. 2nd ed. 1992. p. 365-92.
References: 12. Transfer resistant high lusture lipstick
compositions United States patent 6036947.
1. P.P Sharma, cometics- formulation,
th 13. Monti D, Saccomani L, Chetoni P, Burgalassi S,
manufacturing & quality control 4 ed, 291-292.
Saettone MF, Mailland F. In vitrotransnungual
2. Swarnalata saraf, shailendra saraf, cosmetics, a
Permeation of Ciclopirox from a Hydroxy
practical manual, pg.10.
propyl Chitosan Based, water soluble Nail
3. United States pharmacopoeia, 2002.
lacquer. Bio Pharmaceutics University of Pisa,
4. Indian pharmacopoeia, volume-II, 1996
Italy. Drug Dev Ind Pharm 2005; 31:11-7.
5. Schlossman ML. Manufacturing process for color
14. Young EG, Wentworth HP. Hawkins WW. The
cosmetics. Cosmetic Toiletries 1986; 101:195-
absorption and Excretion of allantoin in
202.
mammals. J Pharmacol Exp Ther 1944; 81:1-9.
6. Simmons JV. The science of cosmetics. 2nd ed.
15. Iwasaki Y. Hydrophilic interaction
1995. p. 139
chromatography-Electro spray ionization mass
7. Nanda S, Nanda A, Khar RK. Cosmetic
spectrometry for determination of allantoin in
Technology 2006-2007; 1-8, 330-53.
human biological samples 19 Aug 2004.
8. Formulation and evaluation of medicated lipstick
16. British Pharmacopoeia. Her Mejesty's
of allaintoin, Asian journal of pharmaceutics,
Stationery Office: London: 2004. p. 75-6.
2005; 2-2, 91-95.
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