DEPARTMENT OF PATHOLOGY CMC, LARKANA

PATHOLOGY TEST 3rd YEAR MBBS (B-41),

Dated: 12-09-15 Time allowed: 40 min Marks: 70

Instructions:

1. Before solving the papers Check & Verify the pages and question Nos. in the papers. Any deficiney
must be reported to the invigilator.
2. Write down Name, Roll No & Signature on top of each page of paper.
3. Attempt all questions.
4. Each question (stem) has five statements, select among one best.

Q.1 Most common site of mural thrombi is: Q.7 Cell response to increase demand by:
a. Arterioles a. Hyperplasia
b. Cardiac chambers b. Metaplasia
c. Capillaries c. Apoptosis
d. Medium sized arteries d. Atrophy
e. Superior vena cava e. Dysplasia
Q.2 Main function of Nitric Oxide is: Q.8 Man with long standing hypertension who
a. Platelet aggregation died of a stroke which of the following changes
b. Vasoconstriction occurs in heart section:
c. Vasodilation a. Liquefaction
d. Platelet adhesion b. Caseous
e. Fibrinolysis c. Coagulative
Q.3 Von-Willebrand factor is responsible for: d. Enzymatic
a. Platelet aggregation e. Fibrinoid
b. Platelet adhesion Q.9 Which of the following morphological
c. Fibrinolysis myocardial finding is an indicator of irreversible
d. Activation of protein C injury:
e. Vasoconstriction a. Cell blebs
Q.4 In DVT patient, edema in leg occur due to: b. Myelin figures
a. Acute inflammation c. Pyknotic nuclei
b. Hypoprotenemia d. Mitochondrial swelling
c. Increase hydrostatic pressure e. Depletion of glycogen
d. Malnutrition Q.10 Old man has complained of mild burning at
e. Immobilization substernal epigastric pain following meals for
Q.5 Edema is in CCF occur due to: past three years which of the following mucosal
a. Hypoprotenemia alteration is most likely represented by these
b. Malnutrition findings:
c. Increase cardiac output with activation of a. Dysplasia
renin angiotensin system b. Hyperplasia
d. Decrease cardiac output with activation c. Carcinoma
of renin angiotensin system d. Ischemia
e. Decrease plasma osmotic pressure e. Metaplasia
Q.6 Pulmonary edema most commonly occur in:
a. Acute respiratory distress syndrome
b. Renal failure
c. Hypersensitivity reaction
d. Pulmonary infection
e. Left ventricular failure
Q.11 Old woman has had episodes of right upper Q.18 Keloid formation occurs due to formation
quadrant pain the past two weeks. Her stool of:
have been pale in color and serum bilirubin a. Excessive granulation tissue
09mg/dl, resulting in obstruction of biliary tract b. Excessive collagen
which of the following cellular alteration c. Inadequate granulation tissue
visualized on her skin. d. Inadequate collagen
a. Icterus (yellowness) e. Excessive angiogenesis
b. Hemosidrosis Q.19 Chief source of infection by staphylococcus
c. Steatosis aureus is:
d. Calcification a. Oro - faecal route
e. Lipofuscin deposition b. Direct contact
Q.12 Dystrophic calcification is most closely c. Contaminated water
associated with: d. Nosocomial infection
a. Diminished blood flow e. Chronic- nasal carriage
b. Necrosis Q.20 Toxic shock syndrome is caused by:
c. Hypercalcemia a. Staphylococcus saprophyticus
d. Chronic irritation b. Staphylococcus epidermidis
e. Increased work load c. Staphylococcus aureus
Q.13 Immediate transient response: d. Streptococcus pyogenes
a. Is irreversible change e. Streptococcus pneumoniae
b. Is caused by ultraviolet rays Q.21 The form of malaria parasite transmitted to
c. Affects venuless only human by mosquito is:
d. Is caused by IL-8 a. Sporozoites
e. Occurs 01 hour after injury b. Gametocytes
Q.14 Transmigration of leukocytes across the c. Merozoites
endothelium is produced by: d. Trophozoites
a. P-Selectin e. Schizonts
b. E-Selectin Q.22 Type of anemia in malaria is:
c. PECAM a. Iron deficiency anemia
d. Integrins b. Megaloblastic anemia
e. Sialyl Lewis-X c. Sickle cell anemia
Q.15 Pain in acute inflammation is produced by: d. Hemolytic anemia
a. Histamine e. All of the above
b. Serotonin Q.23 Giardiasis infection is diagnosed in Lab by
c. Leukocrienes finding of following in stool examination:
d. Prostaglandins a. Trophozoites
e. Thromboaxane=A2 b. Cysts
Q.16 Tissue destruction is mostly produced by: c. Sprozoties
a. Nitric oxide d. Schizonts
b. IL-I e. Eggs
c. Tumor necrosis factor chemokines Q.24 Enterobiasis is a diagnosed by following
d. Lysosomal enzymes of leukocytes test method:
e. Chemokines a. Scotch tape method
Q.17 Langhan’s type of giant cell are mostly b. Direct examination of eggs in stool
focused in: c. Serology
a. Sarcoidosis d. PCR
b. Syphilis e. Peripheral blood film
c. Leprosy
d. Tuberculosis
e. Xanthoma
Q.25 Blistering and ulceration caused by Q.30 In bacterial growth cycle the beta lactum
dranculus medinesis is usually found on: drugs such as penicillin acts during:
a. Whole body a. Lag phase
b. Lower extremities b. Log phase
c. Upper extremities c. Stationary phase
d. Head & neck area d. Decline phase
e. Scrotal region e. Death phase
Q.26 The severe manifestation of T.solium Q.31 Which of the following are flexible and thin
include: walled bacteria:
a. Space –occupying lesion a. Legionella
b. Inflammatory lesion b. Bacteroides
c. Ulcerative lesion c. Rickettsia
d. Neurocystcercosis d. Chlamydia
e. Benign lesion e. Treponema
Q.27 Ascaris lumbricoides is: Q.32 Regarding exotoxin:
a. Tape worm a. Secreted from cell
b. Round worm b. Source is cell wall of gram negative
c. Flat worm bacteria
d. Giant round worm c. Lypopolysaccharide in nature
e. Pin worm d. Genes located on bacterial chromosome
Q.28 Diagnosis of ascariasis is usually made by: e. Poorly antigenic
a. Detection of eggs in sputum Q.33 Disinfectant used to treat swimming pools
b. ELISA test of blood is:
c. PCR test of blood a. Formaldehyde
d. Culture of blood b. Glutraldehyde
e. Larvae of ascris lumbricoides in stool c. Iodine
Q.28 Lab diagnosis of schistosomiasis is carried d. Chlorine
by examining the: e. Ethylene
a. Urine Q.34 The bacterial spore is:
b. Sputum a. Usually extracellular
c. Blood b. Has high metabolic activity
d. Rectal biopsy c. Remain dormant for many years
e. Antibody detection d. Extraordinary sensitive to heat
Q.29 The DNA of Prokaryotes contains about: e. It germinates to produce two bacteria
a. 1000 genes Q.35 The main function of bacterial capsule is:
b. 2000 genes a. Helping in motility
c. 3000 genes b. Acts as Exotoxin
d. 4000 genes c. Acts as antiphagocytic
e. 5000 genes d. Help in staining of bacteria
e. Give resistance to bacteria against
chemicals
 DEPARTMENT OF PATHOLOGY CMC, LARKANA.
SEQ TEST OF PATHOLOGY 3rd YEAR MBBS (B-41),

Dated: 12-09-15 Time allowed: 30 min Marks: 30

Instructions:
1. Write down your Name, Roll No & Signature on top of each page of paper.
2. Attempt all questions
3. All question carry equal marks.

Q.1
a. What are the morphological features of chronic lung congestion
b. Name the anti-thrombotic factors release from endothelium

Q.2
a. What is difference between necrosis and apoptosis.
b. Give examples of the metaplasia.

Q.3
c. Define phagocytosis.
d. Describe MPO-halide system of phagocytosis.

Q.4
a. Name intestinal protozoan parasite.
b. Shortly describe the life cycle of E.histolytica.

Q.5
a. Name post streptococcal diseases
b. Briefly describes importance of ASO titer

Q.6
a. What is plasmid & mention its types.
b. What are the various functions of bacterial capsule