Chem 40 Problem Set 8 (Lipid metabolism)

Please answer the following in a brief and concise manner. Use 4-5 lines of the yellow paper.

1. Give the reaction (substrate, enzyme, product, cofactor, or coupled reaction) referred to in
the following:
a. Activation of fatty acid for catabolism
b. The reaction in β-oxidation that produce FADH2
c. The nonhydrolytic cleavage in β-oxidation
d. The isomerization reaction in the β-oxidation of unsaturated fatty acids
e. The first step in palmitate synthesis

2. How many total ATPs will be produced if a fatty acid with 18:1∆9 symbol enters the β-
oxidation pathway, all the acetyl-CoA produced enters the citric acid cycle, and all the
reduced cofactors enter oxidative phosphorylation.

3. Give two factors that prevent fatty acid synthesis and degradation to occur at the same
time at the same extent.