Molecular Biology and Biotechnology

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Carbohydrate Polymers 25 (1994) 61 -62

' 1994 Elsevier Science Limited.


Printed in Great Britain. All rights reserved

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Book reviews

Molecular Biology and Biotechnology. Edited by J.M. Chitin Enzymology. Edited by R.A.A. Muzzarelli,
Walker and E.B. Gingold, The Royal Society of Chem- European Chitin Society, Ancona, 1993. xiv + 508 pp.
istry, 1993. xviii + 428 pp. Price £39.00. ISBN 0-85186-
794-4. Chitin occurs in a variety of organisms, including fungi,
algae, protozoans and arthropods. The enzymes
Books on molecular biology and/or biotechnology are involved with synthesis, lysis and modification of chitin
in great demand nowadays as most organisations and control essential functions, such as body protection and
institutions are investing a lot of financial, material and support, defense mechanisms, pathogenicity, digestion
human resources to fund and facilitate the research and and ecological equilibria. A better understanding of the
development in the fields of biotechnology. This popu- structure and mode of action of these enzymes has been
lar field of research covers a wide scope of activities and made possible by biochemical methods, analytical tech-
areas. Hence, this third edition of 'Molecular Biology niques and genetic manipulation. A number of research
and Biotechnology' can provide the basic knowledge as groups have made excellent progress in identifying genes
well as give information on the latest developments to coding for chitinase and chitin synthase. Considerable
the reader. effort has also been put into isolating and purifying
The 19 chapters cover the following topics: Fermen- chitin synthase, but separation of this enzyme from
tation Technology, An Introduction to Recombinant strong associated lipids and other proteins has been
DNA Technology, The Polymerase Chain Reaction, difficult.
The Expression of Foreign DNA in Bacteria, Yeast 'Chitin Enzymology' represents a collection of papers
Cloning and Biotechnology, Cloning Genes in presented at the International Symposium under the
Mammalian Cell-Industry, The Current Impact of same name held in Senigallia, Italy. It comprises the
Recombinant DNA Technology in the Food Industry, most recent advances in the fields of chitin synthesis,
DNA Profiling in Forensic Science, Molecular Diag- lysozymes, chitinases, cloned enzymes and chemical
nosis of Inherited Disease, Vaccination and Gene aspects.
Manipulation, Transgenesis, Enzyme Engineering, Among the many interesting topics covered are: the
Stability of Enzymes Cells, Immobilised Biocatalysts, transglycosylase activity of chitinase; the purification
Downstream Processing, Monoclonal Antibodies, and and characterisation of membrane-demand chitin
Biosensors. The chapters are arranged quite system- synthase from Absidia glauca: the isolation and char-
atically in which the presentations can be classified into acterisation of chitin deacetylase; the enzymatic degra-
several main topics like Fermentation Technology, dation of chitin and chitosan; and the role of exogenous
Recombinant DNA Technology, Gene Cloning, Plant chitosans in human wound tissues.
Biotechnology, Application of Molecular Biology in This book is an important research reference tool for
Various Industry and finally the Current Development those working in this field and is recommended to all
in Biotechnology which covers Enzyme Immobilisation libraries concerned with carbohydrates, biochemistry
Technology, Monoclonal Antibodies and Biosensors. and molecular biology.
We tbund the book had been thoroughly revised and
updated, combining entirely new information on John F. Kennedy
current hot topics with upgrading of the existing chap- Marion Paterson
ters. The contents were aided by illustrations and
examples to guide the readers to comprehend the
subjects. In conclusion, the contributions in this book Chemistry and Biology of (1 -~ 3)-/~-Glucans. Edited by
are obviously suitable for teaching purposes, i.e. for B.A. Stone and A.E. Clarke, La Trobe University Press,
undergraduates. However, the simple presentation of 1992. xi + 303 pp. Price AU$175.00. ISBN 1-86 324-
the book should also be helpful to researchers from 409-3.
other fields of training who require a basic introduction
and understanding in this area. Glucan biopolymers are readily abundant particularly
those with a (1 ---+3)-fl-D-glycosidic linkage as a major
J.F. Kennedy feature which can be found in many plants and micro-
W.H.W. Hasamudin organisms. The main functions of these polysaccharides

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