Tabel 2.

Characteristics of studies included in this systematic review

Author Purpose Population and Group Research Intervention Instrument Result
Sample Research design and
Comparison

Marsh et Assess the 96 women with PCOS Randomized intervention Insuln sensitivity The rate of decline was
al (2013) effectiveness of aged 18-40 years with a control trial, with a low index, oral high in both groups
America a low-calorie BMI ≥25kg / m2 have clinical glycemic and flucose tolerance (49%). Compared to
diet (low not been losing weight control trial group diet test (ISI OGTT), women who consume
glycemic diet) lately, are not with low program Homeostatic conventional healthy
on insulin breastfeeding, are not glycemic model assesment diets, more women who
sensitivity in pregnant and are not diet and comparison: (HOMA), consume low GI diets
PCOS cases planning a pregnancy conventional intervention (HOMA2) show improved
program. diet with a menstrual cycle (95%
intervention. convensioanl compared to 63%, active
The group was divided Diet carried diet program respec; P = 0.03).
into 2 groups with 50 out for 12 Among the biochemical
respondents on a diet weeks. steps, only serum
program 1 (low glycemic Fibrinogen
diet) and 46 on a diet concentrations show
program 2 (conventional significant differences
diet). between diet (P, 0.05)
Karimii Assess the 88 women with PCOS Randomized Group 1 formula: HOMA- Applesin concentration
et al effects of ranging in age from 18- control trial, received (insulin fasting 36 decreased
(2018) synbiotic 40 years were divided randomised synbiotic × fasting significantly in the
United supplementation into two groups of 44 double supplement (mIU / l blood synbiotic group, from 27
Kingdom on metabolic each. The treatment blinded treatment glucose (mg / (SD 21) nmol / l at
parameters and group intervened in the plasebo dl)) / 405 (or baseline to SD 4 · 14 · 4
apelin in woman administration of a control trial Group 2 (fasting insulin×2 (SD 4.5) nmol / l after 3
with polysyclic synbiotic supplement in placebo (mIU / l) months, compared with
ovary syndrome the control group with a intervention fasting blood an important nonm
placebo. glucose (mmol / increase in the placebo
l)) / 22 · 5). group between baselines
Author Purpose Population and Group Research Intervention Instrument Result
Sample Research design and
Comparison

Quantitative at baseline 8 -26 (SD

insulin sensitivity 15) nmol / l and 3
check index months at 18 · 4 (2.9)
(QUICKI) was nmol / l.
used to
determine
the degree of
insulin sensitivity
using the
following
formula: 1 / (log
fasting glucose +
log fasting
insulin)

Laura To asses 41 women with PCOS a single- Group 1 1. DAILY (Diet Changes in the mean
et.al. evectiveness of randomized to the pulse blind, received Approaches fasting glucose were -
(2017) a pulse-based based or TLC diet who parallel, intervention to Increase 0.18 and 0.14 mmol/L
diet on infertility aged 18-35 years, with stratified pulse-based Lentils in for the pulse-diet group
measures and symptoms of missed or randomized diet Youth) and TLC group,
metabolic irregular menstrual clinical trial. questionnaire respectively, with a
syndrome risk periods. Group 2 2. Quality-of- population standard
received Life deviation of 0.46 and an
intervention Questionnair effect size of -0.70.
TLC diet e for Women
with
Polycystic
Ovary
Syndrome
Author Purpose Population and Group Research Intervention Instrument Result
Sample Research design and
Comparison

3. Actical™
(MiniMitter,
Bend,
Oregon)
acceleromete
r
4. Clinical
symstoms
such as BMI,
HbA1c,
clood
pressure

Karamali Effects of 60 women with PCOS, randomized, Subjects were 1. Kolmogrov- Overall, probiotic
et. al. Probiotic aged 18-40 years old. double- randomly Smirnov test, supplementation of
(2018) Supplementation blind, assigned into 2 2. The Pearson PCOS women for 12
on Hormonal placebo- groups to chi-square test weeks had beneficial
Profiles, controlled receive was used to effects on total
Biomarkers of trial probiotics and compare testosterone, SHBG,
Inflammation placebo (n = categorical mFG scores, hs-CRP,
and Oxidative 30 each group) variables. TAC and MDA levels
Stress in for 12 weeks. 3. To detect but did not affect other
Women With differences in metabolic profiles.
Polycystic Metabolic anthropometri
Ovary profiles were c measures
Syndrome: A quantified at and in macro-
Randomized, baseline and and
DoubleBlind, after a 12- micronutrient
Placebo- week intakes
Author Purpose Population and Group Research Intervention Instrument Result
Sample Research design and
Comparison

Controlled Trial intervention. between the 2

groups, we
applied
independent t
test.
4. To assess the
effects of
probiotic
supplementati
on on
hormonal
profiles,
biomarkers of
inflammation
and oxidative
stress, we
used one-way
repeated
measures
analysis of
variance
5. Adjustment
for changes in
baseline
values of
biochemical
parameters
was
performed by
Author Purpose Population and Group Research Intervention Instrument Result
Sample Research design and
Comparison

analysis of
covariance
(ANCOVA)
using general
linear models.
Goss et.al To asses 30 women with PCOS Randomized 30 women with Participants lost 3.7% total
(2014) evectiveness of control trial PCOS consumed body fat mass following the
eucaloric reduced- a reduced CHO 8-week reduced-CHO diet
carbohydrate diet diet (41:19:40% arm and 2.2% total fat mass
on body energy from following the 8-week STD
composition and fat CHO:protein:fat) diet (p < 0.001 and p < 0.05,
distribution in for 8 weeks and a resp.) arm. However, only
women with PCOS standard diet the reducedCHO diet resulted
(55:18:27) for 8 in significant decreases in
weeks IAAT, SAAT, and thigh-
IMAT (−7.1%, −4.6%, and
−11.5%, resp., p < 0.01).
The STD diet, but not the
reduced-CHO diet, resulted
in a significant decrease in
total lean mass (−1.3%, p <
0.05).
Change in fat mass was
significantly greater
following the reduced-CHO
diet arm compared to the
STD diet arm after
adjustment for baseline total
fat mass and change in lean
mass (p < 0.05 for difference
between diets.