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Scientific Programme-TCR2020 PDF
Scientific Programme-TCR2020 PDF
Role of Inflammation and Immune System for Cancer Prevention and Treatment
Organized by: Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi-221005, INDIA
& Society for Translational Cancer Research (STCR)
February 13-16, 2020
Scientific Programme
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Day 2: Friday, 14 February 2020
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Session 3B (Invited talks): Cancer diagnostics and target
Venue: Hall A (Ground Floor)
Rapporteur: Akhilesh Kumar
Chairpersons: Arvind M Kayastha and Rakesh K Singh
11:15 AM-11:30 AM Sanjay Yadav (AIIMS Raebareli)
Understanding the role of microRNAs and proteostasis regulating proteins in HNSCC and Lung cancers
11:30 AM-11:45 AM Gauri Misra (NIB Noida)
AGC kinases as drug targets in cancer
11:45 AM-12:00 PM Munish Kumar (University of Allahabad, Prayagraj)
Prognostic value and risk associated with DNA repair gene, GSTs and cytokine gene polymorphism with susceptibility to
lung cancer in North India
12:00 PM-12:15 PM Praveen K Shetty (Nitte University, Mangalore)
Characterization of biomarker and therapeutic target for triple negative breast cancer
12:15 PM-12:30 PM Dinesh Kumar (SGPGIMS Lucknow)
NMR based cancer metabolomics: From biomarkers to disease management
12:30 PM-12:45 PM Manas K Santra (NCCS Pune)
Gatekeeper tumor suppressor FBXO31 abrogates proliferative signaling cascades to prevent breast cancer
tumorigenesis
12:45 PM-1:00 PM Mehdi H Shahi (AMU Aligarh)
Role of sonic hedgehog (Shh)-Gli1 cell signaling pathway in the most common brain tumour glioblastoma
1:00 PM-1:15 PM Sadhana Sharma (AIIMS Patna)
Battling against the extremely high treatment cost of CAR T-cell therapy for hematological malignancies
Session 3C (Award session-Oral presentation by students 1): Immunomodulation and cancer therapy
Venue: Hall A (Ground Floor)
Rapporteur: Pawan Dubey
Chairpersons: Kishore B Challagundla and Om P Singh
11:15 AM-1:15 PM
Gisha R Antony (Regional Cancer Centre, Kerala): Expression of PD-L1 in breast cancer promotes tumor progression and epithelial-
mesenchymal transition
Arathi Rajan (RGCB Kerala): Impact of E-ER signaling on BRCA1 mediated DNA damage repair
Geetu R Varghese (RGCB Kerala): Impact of β-hCG in regulating the immune cell population in BRCA1 mutated breast cancers
Ilakya Selvakumar (SASTRA University, Thanjavur): Significance of micro RNA in endothelial mesenchymal transition in radiation-induced
pulmonary fibrosis
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Ruhi Dixit (IMS, BHU Varanasi): Mutational analysis of sonic hedgehog gene and its association with gallbladder cancer
S Sasikala (Bharathiar University, Tamil Nadu): An epidemological study of environmental pollutants induced breast cancer
Shayani Dasgupta (CNCI Kolkata): RGS5-a crucial contributor in immunomodulation of tumor pericytes
Shilpa Sharma (South Asian University, New Delhi): Extracellular ATP released by the dying cells induce inflammatory cancer metastasis in
chemo resistant cells
Suresh D Sivakalai (University of Madras, Tamil Nadu): C-type natriuretic peptide suppress 7,12-Dimethylbenz[a]anthracene/Croton oil-
induced two-step skin carcinogenesis in male Swiss albino mice: Synergistic actions of CNP and cisplatin
Sushree Sulava (NISER Odisha): Assessment of therapeutic potential of dihydroartemisinin using in vivo glioma models
Usha Singh (IISER Bhopal): Nup62 interaction and stabilization of Nup88 alters NF-kB signaling in cancer
Yama Atri (University of Delhi, Delhi): Cul4A: An oncogenic driver and an attractive chemotherapeutic target for cervical cancer
Kaushik Neogi (IIT BHU, Varanasi):
Shruti Mishra (ISc BHU, Varanasi):
1:15 PM-2:15 PM Lunch and poster session (Poster 1-50)
Session 4A (Invited talks): Cancer cell signaling
Venue: Main Hall (First Floor)
Rapporteur: Shashi Pandey
Chairpersons: Ramesh Chandra and Debabrata Dash
2:15 PM-2:35 PM Kishore B Challagundla (Omaha, USA)
Session 4B (Invited talks): Drug resistance, behavior, herbal medicine and cancer
Venue: Venue: Hall A (Ground Floor)
Rapporteur: Subash C Gupta
Chairpersons: Debapratim K Chowdhuri and Rajiva Raman
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2:15 PM-2:30 PM Hifzur R Siddique (AMU Aligarh)
Drug-resistant castration-resistant prostate cancer: Chemosensitization by lupeol
2:30 PM-2:45 PM Dibyendu Banerjee (CDRI Lucknow)
DNA ligase 1 mediates topoisomerase 1 drug resistance mechanism in colorectal cancer cells
2:45 PM-3:00 PM Anissa A Mirza (AIIMS Rishikesh)
Role of human behavior in cancer prevention
3:00 PM-3:15 PM Hui Tag (Rajiv Gandhi University, Doimukh)
Prospects of traditional wild food and medicinal plants in prevention of inflammation and cancer
3:15 PM-3:30 PM Anu Chandra (Era University, Lucknow)
An investigation on the apoptotic and antioxidant potential of ethanolic extract of wheatgrass
3:30 PM-3:45 PM Shashank Kumar (Central University of Punjab, Bathinda)
Bulbine frutescens: A novel source of notch signaling inhibitor
3:45 PM-4:00 PM Sreejith P Panicker (University of Kerala, Thiruvananthapuram)
Accumulation of metabolites destroys the hair follicle health: An in-vitro and in-vivo approach
4:00 PM-4:15 PM Swapan K Ghosh (Vivekananda Centenary College, Kolkata)
Present status of mushrooms as anticancer and immuno-enhancing agents for cancer management
Session 4C (Award session-Oral presentation by students 2): Nanomedicine, free radicals and cancer stem cells
Venue: Hall B (Ground Floor)
Rapporteur: Om P Singh
Chairpersons: Ranjit K Mishra and Arvind Kumar
2:15 PM-4:15 PM
Anil K Deshantri (University Medical Center Utrecht, Netherland): Liposomal drug delivery in cancer: hematological malignancies and beyond
Ankita Umrao (DY Patil University, Mumbai): Integrative cancer therapy with a novel antioxidant herbal formulation: in-vivo study
Aparna Menon A (University of Calicut, Kerala): Studies on the synthesis of biogenic silica nanoparticles and its effects as a drug carrier in
epirubicin based cancer therapy
Archana MG (Regional Cancer Centre, Kerala): Doxorubicin endowed polysaccharide capped gold nanoparticles as novel agents for cancer
therapy
Lekhika Pathak (IIT Guwahati): Identification of a novel immunosuppressive and inflammatory stemness pathway in cancer stem cells:
implication in cancer immunotherapy
Seema Bhuyan (IIT Guwahati): Mesenchymal stem cell altruism mediates a novel HMGB1/NKG2D immune response in oral cancer
Suchisnigdha Datta (CNCI Kolkata): Redox regulation of nrf-2 in lung cancer cells by tea: implication in cancer chemo-therapeutics and chemo-
sensitization
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Sunil Gowda SN (SASTRA University, Tamil Nadu): Radiation-induces H3K9 methylation on E-cadherin promoter mediated by ROS/Snail axis
during lung EMT: Exploring the role of G9a in radiation signaling
Md. Rizwanullah (Jamia Hamdard, New Delhi): Development of exemestane encapsulated TPGS polymer lipid hybrid nanoparticles:
optimization and in vitro assessments
Tanmay Bera (Vivekananda Centenary College, Kolkata): Effects of terpenoid (Hexane extract) isolate of Ramaria sp, as anti-cancerous agent,
against breast cancer cell line
Tapojyoti Sanyal (Vivekananda Centenary College, Kolkata): Study of F8 fraction (water extract) from Lentinus edodes against breast cancer
cell lines as anti-cancerous agents and its immunomodulatory effects on mice splenocyte
Nikee Awasthee (ISc BHU, Varanasi):
Akata Saha (CNCI, Kolkata): Intra-tumoral VEGF promotes switching of Th17 cells towards Treg cells
Vivek K Soni (Guru Ghasidas Vishwavidyalaya, Bilaspur): Chemo-sensitization activity of Curcumin in Hepatic Carcinoma Cell (Hep-G2)
4:15 PM-4:30 PM Tea Break
Session 5A (Invited talks): Oncogenes and cancer
Venue: Main Hall (First Floor)
Rapporteur: Rashmi Singh
Chairpersons: Kapil Mehta and Ramadevi Nimmanapalli
4:30 PM-4:55 PM Deepa Sampath (Ohio, USA)
Biology and targeting of mutant p53 in leukemia
4:55 PM-5:15 PM Shovan K Majumder (RRCAT Indore)
Optical Spectroscopic Technology- Towards Clinical Diagnosis of Oral Cancer
5:15 PM-5:35 PM Satya N Das (AIIMS New Delhi)
6-Gingerol inhibits growth of oral squamous cell carcinoma by targeting Akt/mTOR signalling pathway
5:35 PM-5:55 PM Virendra N Pandey (New Jersey, USA)
Molecular mechanism of tumorigenesis promoted by FUSE binding protein 1: A potential target for anticancer drug
development
5:55 PM-6:15 PM Alo Nag (University of Delhi, New Delhi)
Understanding the oncogenic mechanisms of FoxM1
6:15 PM-6:35 PM Vibha Tandon (JNU New Delhi)
Development of radiosensitizers for cancer radiotherapy through repurposing of drugs suggested by informatics
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4:30 PM-4:45 PM Subhrajit Biswas (Amity University, Noida)
Translational approach to inhibit nonresolving inflammation and angiogenesis alerting survival signals to prevent
hepatocarcinogenesis
4:45 PM-5:00 PM Naveen K Vishvakarma (Guru Ghasidas Vishwavidyalaya, Bilaspur)
Anti-inflammatory drugs for immunopotentiation in cancer
5:00 PM-5:15 PM PallabiKalita Hui (NIT, Yupia)
Pharmacological, antioxidant and anticancer studies of some selected medicinal plants of Arunachal himalayan region
5:15 PM-5:30 PM Umesh CS Yadav (Central University of Gujarat, Gandhinagar)
Prevention of cigarette smoke-induced ECM modulation by Fisetin in lung adenocarcinoma cells
5:30 PM-5:45 PM Neelam Yadav (RML Avadh University, Faizabad)
Efficient reconstitution of hepatic microvasculature by endothelin receptor antagonism in liver sinusoidal endothelial
cells by protection from inflammation-induced mitochondrial impairment and DNA damage
5:45 PM-6:00 PM Madhumita Roy (CNCI Kolkata)
Several factors contributing to iAs induced skin carcinogenesis may be modulated by black tea
6:00 PM-6:15 PM Santosh Kumar (NIT Rourkela)
Identification of lncRNA ribosnitches and their binding proteins involved in cancer
6:15 PM-6:30 PM Aklank Jain (Central University of Punjab, Bathinda)
Circulating miR-590-5p acts as tumor suppressor via targeting STAT3 pathway in non-small cell lung cancer
Session 5C (Award session-Oral presentation by students 3): Metabolome and cancer chemoprevention
Venue: Venue: Hall A (Ground Floor)
Rapporteur: Chandan Singh
Chairpersons: Ajaikumar B Kunnumakkara and Perumana Sudhakaran
4:15 PM-6:15 PM
Ajeesh BL (Regional Cancer Centre, Kerala): Role of glucose transporter (GLUT)-1, as a potential target in human breast cancer therapy
Arundhati Mehta (Guru Ghasidas Vishwavidyalaya, Bilaspur): Eugenol in Anti-Neoplasm Armamentarium: Morphological Alterations &
Molecular Interactions
Himanshu Dhanda (University of Delhi): Effect of bleomycin on SMAD-2,3,5, TGF-β signaling and epithelial-mesenchymal transition in A549
lung adenocarcinoma cell line
Ishant Arora (National Institute of Homoeopathy, Kolkata): The Anti-mitotic action of plant derived anti-cancer drugs in homoeopathy
Kalpana Pal (University of Baroda, Vadodara): Chemo-profiling of Taverniera cuneifolia Roth (Ali) and investigations on its anti-cancer property
in lung cancer
Koushik Pandey (Vivekananda Centenary College, Kolkata): Study of mycochemistry and anticancerous activity of Astraeus hygrometricus on
MCF-7 cell line
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Parvathy Venate (IMS, BHU Varanasi): Evaluation of GP (Gudūci and Pippali) compound with special reference to its anti-cancerous and
immunomodulatory activity - an in vitro study
Prabhat Tiwari (National Institute of Homoeopathy, Kolkata): Cancer Therapy: Modern Medicine and Homoeopathy- an integrative approach
Rachna Goenka (National Institute of Homoeopathy, Kolkata): Cancer Therapy by the tree of life-thuja occidentalis
Sulfath TP (Regional Cancer Centre, Kerala): Verteporfin inhibits proliferation and metastasis in breast cancer cells via regulating YAP activation
Sumit S Verma (ISc BHU, Varanasi):
Vipin Rai (ISc BHU, Varanasi):
Kruti A Mehta (GCRI, Ahmedabad): Aberrant Glycosylation in Oral Cancer: Can Nature be the Remedy?
Vivek Akhouri (Anugrah Narayan College, Patna): Therapeutic effects of Pterocarpus santalinus seeds against DMBA induced breast cancer in
rats
7:00 PM-8:00 PM Cultural programme
8:00 PM-10:00 PM Dinner
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Day 3: Saturday, 15 February 2020
Page 9 of 13
Venue: Venue: Hall A (Ground Floor)
Rapporteur: Shreyans K Jain
Chairpersons: Ankush Gupta and Chandan Singh
11:15 AM-11:30 AM Sada N Dwivedi (AIIMS New Delhi)
Effectiveness of regimens used under Neo-adjuvant Chemotherapy in Treatment of Breast-Cancer: Network Meta-
Analysis
11:30 AM-11:45 AM Anil M Limaye (IIT Guwahati)
Estrogen regulation and DNA methylation converge on intron-2 to modulate cystatin A expression in breast cancer cells
11:45 AM-12:00 PM Meena Jhanwar-Uniyal (New York, USA)
Molecular sequence of events and signaling pathways in cerebral metastases
12:00 PM-12:15 PM Navneet Agnihotri (Panjab University, Chandigarh)
Is cholesterol homeostasis an aberration or clinically relevant: A study in colorectal cancer
12:15 PM-12:30 PM Gaurav Kaithwas (BBAU Lucknow)
Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland
chemoprevention
12:30 PM-12:45 PM Chandi C Mandal (Central University of Rajasthan, Ajmer)
Targeting osteoblast-like potential in cancer cells
12:45 PM-1:00 PM Chandramani Pathak (IIAR Gandhinagar)
Cellular dynamics of FADD in regulation of NLRP-3 inflammasome and cell death signaling in Cancer
1:00 PM-1:15 PM Sumit Aggarwal (ICMR New Delhi)
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1:15 PM-2:15 PM Lunch and poster session (Poster 51-100)
Session 8 (Invited talks): Cancer prevention-I
Venue: Main Hall (First Floor)
Rapporteur: Sanjeev K Yadav
Chairpersons: Shyam Sundar and Sukh M Singh
2:15 PM-2:55 PM Acharan S Narula (North Carolina, USA)
Inflammation, immunity and cancer: When the “Standard of Care” has been exhausted, what is next? Successful
outcomes with botanicals and natural products
2:55 PM-3:15 PM Kashi N Prasad (Apollo Hospital, Lucknow)
Helicobacter pylori infection in etiopathogenesis of gastric Cancer
Session 9 (Panel discussion): Is India ready to tackle the looming issue of cancer? How can clinical and translational cancer research help?
Venue: Main Hall (First Floor)
3:15 PM-4:45 PM
Rapporteur: Gyan P Modi
Moderator: Pankaj Chaturvedi (Tata Memorial Center, Mumbai)
Panelists: Vijay K Shukla, Vaskar Saha, Vinay K Puduvalli, Satyajit Pradhan, Varsha Gandhi, Bharat Aggarwal, Sen Pathak, Kapil Mehta
5:00 PM-10:00 PM Ganga Aarti, Cultural Programme and Gala-Dinner
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Day 4: Sunday, 16 February 2020
8:00 AM-9:00 AM Registration and breakfast
Session 10 (Invited talks): Epigenetics of cancer
Venue: Main Hall (First Floor)
Rapporteur: Ankush Gupta
Chairpersons: Rama S Dubey and Prabhudas S Patel
9:00 AM-9:35 AM Tapas K Kundu (CDRI Lucknow)
Epigenetic regulation of oral cancer: Targets for therapeutics
9:35 AM-9:55 AM Hari S Sharma (Amsterdam, Netherland)
Perpetuated inflammation and angiogenesis in human chronic lung diseases and cancer
9:55 AM-10:15 AM Inder K Gadi (North Carolina, USA)
Snp microarray utilization for diagnosis of clinically significant changes in hematological malignancies
10:15 AM-10:35 AM Parag Mehta (Massachusetts, USA)
Higher-order therapeutic (HOT) TM drug for the treatment of head and neck cancer
10:35 AM-10:55 AM Arvind Singh Negi (CIMAP Lucknow)
Fragment based drug discovery approach: Trimethoxyphenyl as an antitubulin fragment
10:55 AM-11:15 AM Manoj K. Bhasin (Georgia, USA)
Single-cell multiomics: unraveling inflammation role in diseases and therapeutic responses, one cell at a time
11:15 AM-11:30 AM Tea Break
Session 11A (Invited talks): Cancer prevention-II
Venue: Main Hall (First Floor)
Rapporteur: Ram S Mishra
Chairpersons: Parag Mehta and Lal C Rai
11:30 AM-11:50 AM Prabhudas S Patel (GCRI Ahmedabad)
Insight into molecular mechanisms of HPV infected cervical cancer
11:50 AM-12:10 PM Anil Kumar (NII New Delhi)
Towards understanding the link between intestinal microbiota and colorectal cancer
12:10 PM-12:30 PM Jyoti P Chaudhuri (Jena, Germany)
The spatial order of chromosomes in context of cure and prevention of cancer
12:30 PM-12:50 PM Rakesh K Tyagi (JNU New Delhi)
Genomic bookmarking by nuclear receptors: a novel dimension to epigenetic control
12:50 PM-1:10 PM Junichi Fujii (Yamagata, Japan)
Prevention of diethylnitrosamine-induced hepatic injury and carcinogenesis in mice by vitamin C
1:10 PM-1:30 PM Bechan Sharma (University of Allahabad, Prayagraj)
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The balance between the rates of incorporation and pyrophosphorolytic removal influences the HIV‐1 reverse
transcriptase bypass of an abasic site with deoxy‐, dideoxy‐, and ribonucleotides
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