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Ebn 3
Ebn 3
A. Clinical question
P- Patients with surgical incision
I- Application of topical antibiotic
C- No application of topical antibiotic
O- The objective was to determine whether the application of topical antibiotics to surgical
wounds that are healing by primary intention reduces the incidence of surgical site infection.
B. Resources searched
425 Results
C. Identification of research
Item Information about the item
Study ID or code FEU-1, Etc.
Authors and year Author/s names and year of publication
Study subjects Patient’s with wound
Best practices Statements best related to our selected topic
Saco, M., Howe, N., Nathoo, R., & Cherpelis, B. (2014). Topical antibiotic prophylaxis for
prevention of surgical wound infections from dermatologic procedures: a systematic review and
meta-analysis. Journal of Dermatological Treatment, 26(2), 151–158. doi:
10.3109/09546634.2014.906547
Toussaint, J., Chung, W. T., Osman, N., Mcclain, S. A., Raut, V., & Singer, A. J. (2015). Topical
Antibiotic Ointment Versus Silver-containing Foam Dressing for Second-degree Burns in
Swine. Academic Emergency Medicine, 22(8), 927–933. doi: 10.1111/acem.12723
Poovelikunnel, T., Gethin, G., & Humphreys, H. (2015). Mupirocin resistance: clinical implications
and potential alternatives for the eradication of MRSA. Journal of Antimicrobial
Chemotherapy, 70(10), 2681–2692. doi: 10.1093/jac/dkv169
Edmiston, C. E., Leaper, D., Spencer, M., Truitt, K., Fauerbach, L. L., Graham, D., & Johnson, H. B.
(2017). Considering a new domain for antimicrobial stewardship: Topical antibiotics in the open
surgical wound. American Journal of Infection Control, 45(11), 1259–1266. doi:
10.1016/j.ajic.2017.04.012
Phillips, M., Rosenberg, A., Shopsin, B., Cuff, G., Skeete, F., Foti, A., … Bosco, J. (2014).
Preventing Surgical Site Infections: A Randomized, Open-Label Trial of Nasal Mupirocin
Ointment and Nasal Povidone-Iodine Solution. Infection Control & Hospital Epidemiology, 35(7),
826–832. doi: 10.1086/676872
Heal, C., Lepper, P., & Banks, J. (2017). Topical antibiotics to prevent surgical site infection after
minor surgery in primary care. Dermatology Practical & Conceptual, 7(3), 16–20. doi:
10.5826/dpc.0703a03
Mchugh, S. M., Collins, C. J., Corrigan, M. A., Hill, A. D. K., & Humphreys, H. (2011). The role of
topical antibiotics used as prophylaxis in surgical site infection prevention. Journal of
Antimicrobial Chemotherapy, 66(4), 693–701. doi: 10.1093/jac/dkr009
López-Cano, M., Kraft, M., Curell, A., Puig-Asensio, M., Balibrea, J., Armengol-Carrasco, M., &
García-Alamino, J. (2019). Use of Topical Antibiotics before Primary Incision Closure to Prevent
Surgical Site Infection: A Meta-Analysis. Surgical Infections, 20(4), 261–270. doi:
10.1089/sur.2018.279