A MUTHA S ELVAMANI , P H D

A dd re s s: 1 3 0 8 Ma r kh a m Co u r t , Co l le ge S t a t i o n , T e xa s 7 7 8 4 5
P ho n e : 9 7 9 .4 5 0 . 6 7 5 0 E m ai l : A s e lv a m a n i 1 2 @ g m a i l .c o m
W e b pa ge : ht t p s: / / se lv a man i m e d i c al w ri t i n g . we e b ly . co m; https://www.linkedin.com/in/amutha-selvamani/

P RO F E S S I O N A L S UM M A RY

Innovative biomedical research scientist and program manager with experience leading cross-functional teams through early, late,
developmental and preclinical stages of drug discovery, resulting in several stroke therapeutics. Results-driven and highly analytical
professional with experience managing multiple research projects and spearheading project development resulting in over 15 peer-
reviewed publications. A strategic thinker and planner with proven ability to work effectively in a team- based, fast-paced, deadline-
driven and challenging environment leading to multiple interdisciplinary collaborations. Experience building and maintaining high
performance teams and proficient with risk and decision analysis. Display a high degree of tact and diplomacy and equipped with
excellent verbal, written and presentation communication aptitudes.

E D U CA T I O N

Postdoctoral in Neuroscience, Texas A&M University, Bryan, TX, USA

Postdoctoral Organization, Co-President

Doctor of Philosophy in Molecular Biology (Neuroscience) PhD, Texas Woman's University, Denton, TX, USA
Academic Scholarship | Rosebud Award: Outstanding Campus Leader
Who’s Who Among Graduate Students

Master of Science in Molecular Biology (M.S.), University of Madras, Guindy Campus, Chennai, TN, India

Bachelor of Science in Microbiology, Zoology, and Chemistry (B.S.), Bangalore University–Bengaluru, Bengaluru, KA, India

RE L E V A N T B US I N E S S A N D S O CI A L S K I L L S

o Prepared and monitored compliance for regulatory o Rigorous biostatistical analytics

documents (IRB, IBC)
o Writing Clinical evaluation reports (CER) and
Continuing medical education (CME).
o Medical news writing, Proofreading and copyediting.
o Project Management and resource management
o Grant writing and management
o Mentoring and or training visiting professors, scholars,
graduate students and medical professionals
o Proficient with MS Project, SharePoint, excel and web-
based tools
o Global oral and written communications

T E CHN I CA L S K I L L S

o Translational research: Quantitative bioanalytical
assays of biomarkers (microRNA) in serum of stroke
patients.
o Animal research: Drug treatments, intracranial
surgeries, Adeno-associated Virus-vector delivery
systems, perfusion and behavioral assays.
o Tissue culture: Growing and manipulating
mammalian cells. Transfection and drug treatments.
o Molecular biology: Protein, RNA, DNA and
exosomal extraction and purification. RT-PCR
analysis, RNA sequencing and bioinformatics.
o Immunology: Multiplex chemokine and cytokine
assay analysis.
o Histology: In situ hybridization,
immunohistochemistry and confocal microscopy.

W O RK E X P E RI E N CE

SELVAMANI MEDICAL WRITING, College Station, TX April 2019-Present

Freelance Medical Writer
o Regulatory paperwork (IRB, IBC), creating, reviewing or modifying regulatory documents or SOPs. Texas A&M University,
Bryan, TX
o Clinical Evaluation plans and reports (CEP and CER). Cactus Communications. Mumbai, India
o Writing News article and Continuing Medical Education (CME), proofreading and copyediting . Nascent Medical, LLC.
Atlanta, GA

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 A MUTHA S ELVAMANI , P H D
A dd re s s: 1 3 0 8 Ma r kh a m Co u r t , Co l le ge S t a t i o n , T e xa s 7 7 8 4 5
P ho n e : 9 7 9 .4 5 0 . 6 7 5 0 E m ai l : A s e lv a m a n i 1 2 @ g m a i l .c o m
W e b pa ge : ht t p s: / / se lv a man i m e d i c al w ri t i n g . we e b ly . co m; https://www.linkedin.com/in/amutha-selvamani/
o Expertise in writing clinical study design (inclusion/exclusion criteria), Informed consent document,
Survey/Questionnaire/Data Collection/Abstraction form.

TEXAS A&M UNIVERSITY, Bryan, TX Nov 2019-Present

Research Specialist V, Department of Neuroscience and Experimental Therapeutics (part-time)
o Writing/administrative tasks: Compliance with regulatory paperwork (IBC, IRB, AUP), creating, reviewing or modifying SOPs
and lab protocols, grant preparation, progress reports, planning of Program Project Grants. Facilitating web update and
design
o Research: Observe trainees performing lab procedures, provide guidance and input (e.g., small animal surgery, routine
behaviors, routine analysis eg., infarct volume, data presentation, ELISA assays)
o Train new personnel on stereotaxic surgery, offer refresher workshops

TEXAS A&M UNIVERSITY, Bryan, TX Jul 2015–Dec 2018

Research Assistant Professor, Department of Neuroscience and Experimental Therapeutics
o Prepared regulatory documents (AUP, IRB and IBC) and oversaw that the operations consistently met with regulatory
standards. Supervised all lab employees were GLP certified through the CITI program and were always compliant.
o In charge of coordination and operational management of miRNA profiling, biomarker identification, molecular diagnostics
o and target validation efforts for early drug development of miR-363 as a stroke therapeutic. Consistently met deadlines,
kept within budget, prepared and published scientific reports and manuscripts.
o Applied project management tools to plan and track all internal and outsourced activities to advance drug discovery for a
preclinical stroke study resulting in increased efficiency within the cross-functional team.
o Conducted innovative mechanistic studies using AAV expression systems, coordinated various collaborations in
interdisciplinary fields to facilitate understanding the effect of stroke on alcohol intake and how shift work affects
pathological outcomes following stroke which consequentially brought in 5 new NIH grants.
o Planned and facilitated several national and international symposia and facilitated several symposium sessions.
o Used tools like MATLAB for tracking, coordinating and preparing yearly technical and finance reports, budgets and
resource plans for American heart association grant that resulted in generating pilot data for a NIH grant.

TEXAS A&M UNIVERSITY, Bryan, TX Sep 2010–May 2015

Associate Research Scientist, Department of Neuroscience and Experimental Therapeutics
o Used Integrated Project Management (IPM) methodologies as a research lead in discovering a therapeutic role of IGF-1 in
the aging population and was the first to publish an in vivo evidence for a therapeutic role for miRNA (Let7f and miR1)
following cerebral ischemia and is my most cited article with 111 citations.
o Rendered expert supervision to undergraduate and graduate students with both animal work and molecular biology
techniques
o Trained and directed undergraduate students with their thesis while drafting manuscripts and grants and presenting
research during national and international meetings
o Acquired high visibility among national and international peers by actively presenting and organizing meetings

TEXAS A&M UNIVERSITY, Bryan, TX Feb 2007–Aug 2010

Postdoctoral Research Associate
o Utilized cutting-edge molecular biology techniques to publish pioneering work on estrogen therapy and was promoted
only after 3 years in this role.
o Designed and implemented a new protocol for inducing stroke in an animal model and standardized several behavioral and
molecular assays which formed the foundation for newer projects and subsequent grants worth half a million/yr for 8 yrs.
o Drove key efforts in presenting research at national and international conferences.

P U BL I CA T I O N S

Member of editorial boards:

• Brain Research and Cognitive Neuroscience.

Manuscript reviewer for the following journals:

• Neurorehabilitation & Neural Repair

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 A MUTHA S ELVAMANI , P H D
A dd re s s: 1 3 0 8 Ma r kh a m Co u r t , Co l le ge S t a t i o n , T e xa s 7 7 8 4 5
P ho n e : 9 7 9 .4 5 0 . 6 7 5 0 E m ai l : A s e lv a m a n i 1 2 @ g m a i l .c o m
W e b pa ge : ht t p s: / / se lv a man i m e d i c al w ri t i n g . we e b ly . co m; https://www.linkedin.com/in/amutha-selvamani/
• Journal of Neurology and Experimental Neural Science
• The International Journal of Molecular Sciences
• Gavin Journal of case reports
• International Journal of Environmental Research and Public Health
•
Publications relate to the following major topics and fields:

• Depression
• Stroke
• Circadian rhythm
• Alcohol abuse
• Aging
• Sex difference
• Cardiovascular diseases

Peer-reviewed publications:

Sohrabji F, Selvamani A. Sex differences in miRNA as therapies for ischemic stroke.

Neurochem Int. 2018 Nov 2. pii: S0197-0186(18)30519-9 Review.

Huang CCY, Ma T, Roltsch Hellard EA, Wang X, Selvamani A, Lu J, Sohrabji F, Wang J.

Stroke triggers nigrostriatal plasticity and increases alcohol consumption in rats.
Sci Rep. 2017 May 31;7(1):2501.

Selvamani A, Sohrabji F. Mir363-3p improves ischemic stroke outcomes in female but not male rats. Neurochem Int. 2017
Jul;107:168-181.

Earnest DJ, Neuendorff N, Coffman J, Selvamani A, Sohrabji F. Sex Differences in the Impact of Shift Work Schedules on
Pathological Outcomes in an Animal Model of Ischemic Stroke. Endocrinology. 2016 Jul;157(7):2836-43.

Chisholm N, Henderson M, Selvamani A, Park MJ, Dindot S, Miranda RC and Sohrabji F. Histone Methylation Patterns in
Astrocytes are Influenced by Age Following Ischemia. Epigenetics. 2015;10(2):142-52.

Bake S, Selvamani A, Cherry J, Sohrabji F.Blood brain barrier and neuroinflammation are critical targets of IGF-1-mediated
neuroprotection in stroke for middle-aged female rats. PLoS One. 2014 Mar 11;9(3)

Selvamani A, Williams MH, Miranda RC, Sohrabji F. Circulating miRNA profiles provide a biomarker for severity of stroke
outcomes associated with age and sex in a rat model. Clin Sci (Lond). 2014 Jul;127(2):77-89.

Sohrabji F, Selvamani A, Balden R. Revisiting the timing hypothesis: Biomarkers that define the therapeutic window of
estrogen for stroke. Horm Behav. 2013 Feb;63(2):222-30.

Balden R, Selvamani A and Sohrabji F. Vitamin D deficiency exacerbates experimental stroke injury and dysregulates
ischemia-induced inflammation in adult rats. Endocrinol. Endocrinology. 2012 May;153(5):2420-35.

Lewis D.K, Thomas K.T, Selvamani A and Sohrabji F. Age-related severity of focal ischemia in female rats is associated with
impaired astrocyte function. Neurobiol Aging. 2011 NBA-11383R2.

Selvamani A, Sathyan P, Miranda R.C and Sohrabji F. An antagomir to microRNA Let7f promotes neuroprotection in an
ischemic stroke model. Plos. 2012 February 7(2) e32662.

Selvamani A and Sohrabji F. The neurotoxic effects of estrogen on ischemic stroke in older female rats is associated with age-
dependent loss of IGF-1. J Neurosci. 2010 May 19;30(20):6852-61.

Selvamani A and Sohrabji F. Reproductive age modulates the impact of focal ischemia on the forebrain as well as the effects of
estrogen treatment in a rodent model. Neurobiol Aging. 2010 Sep;31(9):1618-28.

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 A MUTHA S ELVAMANI , P H D
A dd re s s: 1 3 0 8 Ma r kh a m Co u r t , Co l le ge S t a t i o n , T e xa s 7 7 8 4 5
P ho n e : 9 7 9 .4 5 0 . 6 7 5 0 E m ai l : A s e lv a m a n i 1 2 @ g m a i l .c o m
W e b pa ge : ht t p s: / / se lv a man i m e d i c al w ri t i n g . we e b ly . co m; https://www.linkedin.com/in/amutha-selvamani/
Selvamani A, Lincoln C, Uphouse L. (2007). The PKC inhibitor, bisindolymaleimide, blocks DOI's attenuation of the effects of
8-OH-DPAT on female rat lordosis behavior. Behav Brain Research, 179(1):99-106.

Uphouse L, Selvamani A, Lincoln C, Morales L, and Comeaux D. (2005). Mild restraint reduces the time hormone-primed rats
spend with sexually active males. Behavioral and Brain Research, 157: 343-350.

Guptarak J, Selvamani A, and Uphouse L. (2004). GABAA-5-HT1A receptor interaction in the mediobasal hypothalamus. Brain
Research, 1027:144-150.

T E A CH I N G A N D M E N T O RI N G E X P E RI E N CE

Lab Instructor, Anatomy and physiology, Cat anatomy, Comparative anatomy neuroanatomy. Department of Biology, Texas
Woman’s University. 1998-2005
o Lectured and supervised laboratories.

Teaching, Human Gross Anatomy (Thorax/back and Upper Extremity), College of Medicine, Texas A&M University 2008-2010
o Lectured and supervised laboratories. Certified in Evidence-Based Undergraduate STEM Teaching,

Mentoring, Undergraduate, Graduate and Medical students, Texas A&M University 2007-Present
o Managed and mentored over 20 undergraduate, 8 graduate students. Of which 80% of undergrads are in medical
school and 6/8 grad students are doing internship or practicing physicians.

G RA N T S

Current:
2018-2023 Epigenetics of the aging astrocyte: Implications for stroke
Role: Investigator
Funding Source: National Institute of Health (NIH). NIH 1R01AG042189
Funded Grant Amount: $366,250/year

2017-2018 Neuroprotection in the Aging Female Brain

Role: Investigator
Funding Source: National Institute of Health (NIH). NIH/NINDS 2R56NS074895
Funded Grant Amount: $350,00/year
Previous:
2015-2018 MicroRNA363: Cellular and Molecular mechanisms of a novel stroke neuroprotectant
Role: Principal Investigator
Funding Source: American Heart Association (AHA). 15BGIA25880013
Funded grant amount: $70,000/year

2011-2016 Epigenetics of the aging astrocyte: Implications for stroke

Role: Investigator
Funding Source: National Institute of Health (NIH). NIH 1R01AG042189
Funded Grant Amount: $366,250/year

2011-2016 Neuroprotection in the Aging Female Brain

Role: Investigator
Funding Source: National Institute of Health (NIH). NIH/NINDS 1R01NS074895
Funded Grant Amount: $317,031/year

A W A RD S

Office of Faculty Development. College of Medicine. Texas A&M University

o Faculty Development Award, 2017
Society of Neuroscience -Texas A&M Chapter
o Travel Award, 2008, 2011 and 2011

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 A MUTHA S ELVAMANI , P H D
A dd re s s: 1 3 0 8 Ma r kh a m Co u r t , Co l le ge S t a t i o n , T e xa s 7 7 8 4 5
P ho n e : 9 7 9 .4 5 0 . 6 7 5 0 E m ai l : A s e lv a m a n i 1 2 @ g m a i l .c o m
W e b pa ge : ht t p s: / / se lv a man i m e d i c al w ri t i n g . we e b ly . co m; https://www.linkedin.com/in/amutha-selvamani/
Endocrine Society
o Women in Endocrinology Young Investigator Award, 2009
o Eugenia Rosemberg Abstract Travel Award, 2008
o Trainee Poster Award, 2008
Texas Woman’s University
o Outstanding Peer Advisor, 2001, Colors Program
o Outstanding Peer Mentor, 2002, Colors Program
o Outstanding Campus Leader, 2001-2003, Redbud Award

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