Nephron Schematic

Blood Flow Find an error ?

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Na+
Afferent Arteriole
Amino
Glucose
'
Acids ATP
Phosphate
Lactate , or
t
citrate

Cj
o
O Late Distal
tr Tubule & C-
£ 3.
a £
Collecting Duct \ C3
<Q
O
C
_ N
2 a-Intercalated <5 CO
Q> Principal Cells
o (b

cr
* H20 imp. w/o ADH
o> Early Proximal
i

• H20 permeable
Tubule with ADH
•Isosm. abs.
8 Early Distal
Tubule
E
(Q

load -depend . a -/nferca/a/ed

6 * T/ 20 imp. * Reabsorb K
% Dtfutes
£ * Ft excretion
10 4
CO - HCO 3 + H *
C
*+
a
* /VaCf aPs. Aldost stim ’d
A X =CL 5
* ht 2 PO4 excret .
'

T3 A o 7s
+
* NH excret.
;D
0) H 2CO 3
o +
o
o ou_>
V, t8
.
X

+
<D carbonic
anhydras e II
- 13
"C 1:
* O? CL
o p
cr
GO 2+ H2 O oI a £ o
1 CO I D
"
*1

J
O s
o 1 $ a z:
60 QJ
£ X
O 85T 8 CD g HCO3 T H+ H
:£
O
2 Lafe Proximal Tubule N.
9.
05 -2
O Q _
-f
1L KT
ATP
V
-
• isosm. absorption to O 13 No
3 LL
A/ew .A
-
C
H2CO 3 +
Na
+
I # * 2 Cl
K+
HCO 3 c .a . 1L H+
Na+ H
+ 1 v
o
_ +
absorbed
C 07 + H70 fl>
X

03 K a
a>
ATP + _Q Principal Cell “ip

K Cl "
ATP
Na+ * Sec/ ete I* +
" Q
Formate * Add aqf /apqr/rc?
-C Cl"
Na+
+

ADHEpR s
cr SIK +
HP -4

y o
CM
TJ
ThicA
Gs
ATP HP
C
AC K 9T
(D Angiotensin El Stimulated z
4*
CD
Ascending
Limb
foacf-tfepe/Jd.
v cAMP
+
/ “
*
o PKA
Aldosterone Stimulated • P/20 imp.
* 0.3
O

LD " TTJW&S phosphoryl’n Cfl ft

Q ADH (vasopressin ) Stimulated CM
CD §
Q AMP Stimulated 0 ~
O O
(/)

(2) Sympathetic (Norepi.) Stimulated >

Thin Ascending Limb
*T3
•H20 /mpermecijWe
Vasodilator 03
w
Vasoconstrictor Aldosterone increases # of: o
/Wajor effect 1 _ Na+ channels Wl
o
Minor effect 2. Na^-K ^-ATPase pumps o
c/)
* insignificant , unless lots o stim . 3. K+ channels
'
'