DRUG STUDY

Generic Name: paracetamol

Brand Name: Tempra Forte
Classification: Non-narcotic analgesics and antipyretics
Route, Dosage, & Frequency: PO 6.5 ml; q4h PRN
Mechanism of Action: This drug appears to inhibit prostaglandin
synthesis in the CNS and, to a lesser extent, block pain impulses
through peripheral action. Acts centrally on hypothalamic heat-
regulating center, producing peripheral vasodilation (heat loss, skin
erythema, diaphoresis). Therapeutic Effect: Results in antipyresis. Produces analgesic
effect.
Indications: This drug is given to patients for temporary relief of mild to moderate pain,
headache, and fever.
Contraindications: This drug is contraindicated for patients who are hypersensitive to
acetaminophen.
Side Effects: Hypersensitivity reaction (rare)
Adverse Reactions:
Hematologic: Haemolytic anemia, neutropenia, leukopenia, pancytopenia
Hepatic: Liver damage, jaundice
Metabolic: Hypoglycemia
Skin: Rash, urticaria
10 Nursing Responsibilities:

1. If there is fever, assess patient’s fever or pain: type of pain, location, intensity,
duration, temperature, and diaphoresis.
2. Make sure that the drug will be administered within 30 minutes of the scheduled
time and check the drug label at the time of contact with it, before preparing it, and
after preparing it (3 checks before drug administration).
3. Inform the patient and the family about the drug that is about to be taken and also
the side and adverse effects of it.
4. Document the process as well as the time and the date that the medication was
administered.

5. When rashes occur, tell the patient to avoid rubbing or scratching the skin and
advise her to take a bath using lukewarm water. Then, apply a topical lubricant
immediately after taking a bath.
6. Avoid giving patient aspirin or aspirin-like analgesics because it inhibits platelet
aggregation.
7. Evaluate the therapeutic effects of the drug.
8. Educate the patient with the patient’s family to space the doses evenly and to
continue the medication as ordered by the physician.
9. Teach the patient and the patient’s family client warning signs that needs
immediate attention of the physician.
10. Tell the family to consult the physician for use in children with fever lasting longer
than 3 days.