Replikasi sel (K6-K7)

Departemen Biokimia
Fakultas Kedokteran USU
Figure 17-1 Molecular Biology of the Cell (© Garland Science 2008)
Figure 17-2 Molecular Biology of the Cell (© Garland Science 2008)
Figure 17-3 Molecular Biology of the Cell (© Garland Science 2008)
Figure 17-4 Molecular Biology of the Cell (© Garland Science 2008)
Figure 17-47 (part 2 of 2) Molecular Biology of the Cell (© Garland Science 2008)
Figure 17-51a Molecular Biology of the Cell (© Garland Science 2008)
Figure 17-66b Molecular Biology of the Cell (© Garland Science 2008)
Figure 17-48 Molecular Biology of the Cell (© Garland Science 2008)
 DNA Replication and Chromosomes

 During the replication of chromosomes, there is a

cross-over of portions of one DNA strand to another
(of the same chromosome).
 This cross-over, along with randomization assures
that offspring differ from the parents.

meiosis
+
 Chromosomes
Chromosomes
••genomic
genomicDNADNAisisvery
very
long
long
•humans, 6 x 10 9 bp
•humans, 6 x 109 bp
•~1.8
•~1.0meters
meterstotal
total
length
length
••total
totallength
lengthreduced
reducedviavia
associates
associateswith
withproteins
proteins
••individual
individualDNA
DNA
molecules
moleculescondensed
condensed
into
intochromosomes
chromosomes
••humans
humanshave
have22 22pairs
pairs++
X/X
X/XororX/Y
X/Y(ie,
(ie,diploid)
diploid)
Figure 4-6 Molecular Biology of the Cell (© Garland Science 2008)
Pedigree
Pedigree
Pedigree
Pedigree